List Diseases – M
Myasthenic Lambert-Eaton syndrome is characterized by fatigue and muscle fatigue during exercise, which are most pronounced in the proximal part of the lower extremities and the trunk and are sometimes accompanied by myalgias. The involvement of the upper limbs and external muscles of the eyes in the myasthenic syndrome of Lambert-Eaton is observed less frequently than with myasthenia gravis.
Myasthenia gravis is an acquired autoimmune disease, manifested by weakness and pathological fatigue of skeletal muscles. Myasthenia gravis incidence is less than 1 case per 100 000 population per year, and the prevalence is from 10 to 15 cases per 100 000 population. Myasthenia gravis is especially common in young women and men over 50 years of age.
Myalgia is a symptom accompanied by pain in the muscles (diffuse or in a certain group) that occurs both spontaneously and during palpation.
By this syndrome is meant a decrease in muscle tone. This is not an ordinary lack of physical fitness, insufficient training of the muscular system.
Most of the diseases discussed here lead to bilateral proximal weakness and symmetric atrophy (with the exception of proximal diabetic polyneuropathy, neuralgic amyotrophy and, in part, amyotrophic lateral sclerosis) on the arms and legs.
A decrease in skeletal muscle tone (residual tension and muscle resistance to passive stretching) with a deterioration in its contractile function is defined as muscle hypotonia.