Proteins and protein fractions

Learn how proteins and protein fractions testing is performed, how to prepare, and how to interpret results together with a clinician.

Bence Jones Protein: What Does the Analysis Mean?

The urine of a healthy person does not contain Bence-Jones protein, which is represented by light chains of immunoglobulins that are detected as a result of the formation of malignant tumor processes.

PAPP-A: analysis and interpretation of results

In this article, we will discuss the analysis of PAPP-A, a plasma protein whose determination during pregnancy is of considerable importance.

Homocysteine: a marker of cardiovascular risk

Homocysteine is a product of amino acid metabolism (the conversion of methionine to cysteine). Approximately 70% of plasma homocysteine is bound to albumin, 30% is oxidized to disulfide, and only 1% is free.

Blood Ammonia: Diagnosis of Hepatic Encephalopathy

Ammonia is a product of protein metabolism and is formed in all tissues. The largest amount of ammonia (80%) is formed in the intestines under the influence of bacteria.

Uric acid in urine: assessment of urate excretion

Uric acid excreted in urine reflects the intake of purines from food and the breakdown of endogenous purine nucleotides.

Uric acid in the blood: reasons for increase and decrease

Uric acid is a product of the metabolism of purine bases, which are components of complex proteins called nucleoproteins. The resulting uric acid is excreted by the kidneys.

Rehberg-Tareev test: creatinine clearance and SCF

The Rehberg-Tareev test provides an assessment of glomerular filtration and tubular reabsorption in the kidneys. The test is based on the fact that creatinine is filtered only by the glomeruli, is practically not absorbed, and is secreted by the tubules in small quantities.

Creatinine in urine: monitoring of renal excretory function

The daily excretion of creatinine in urine is relatively constant, equivalent to the daily formation and directly depends on muscle mass and the excretory capacity of the kidneys.

Serum creatinine: assessment of kidney function

Creatinine is the end product of creatine breakdown, which plays an important role in the energy metabolism of muscle and other tissues.

Urea in urine: assessment of nitrogen excretion

Urea excretion in urine is proportional to the protein content of the diet, as well as the rate of metabolism of endogenous proteins.

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