Diagnosis of autoimmune diseases

Learn how diagnosis of autoimmune diseases testing is performed, how to prepare, and how to interpret results together with a clinician.

Antinuclear antibody screening: when is an antinuclear antibody test needed?

Antinuclear screening is a laboratory blood test for antinuclear antibodies, which are antibodies that can bind to components of the cell nucleus and nearby cellular structures.

Anti-glutamate decarboxylase antibodies: what the test shows and how it is interpreted

Antibodies to glutamate decarboxylase are autoantibodies against the 65-kilodalton isoform of the enzyme glutamate decarboxylase, which is involved in the synthesis of gamma-aminobutyric acid in nervous tissue and is simultaneously an important autoantigen of pancreatic islet cells.

Antibodies to deamidated gliadin peptides: what the test shows and how to interpret the results

Anti-deamidated gliadin peptide antibodies are a serological marker used when celiac disease is suspected.

Bradykinin antibodies: what does this term mean and what tests are actually needed?

In modern routine medicine, the analysis called "anti-bradykinin antibodies" is not included as a standard diagnostic test for a patient in the main international diagnostic algorithms for bradykinin angioedema and hereditary angioedema.

Cytoplasmic antibodies: what the test shows, how it is interpreted, and for which diseases it is especially important

In modern rheumatology, nephrology and clinical immunology, the term "cytoplasmic antibodies" most often refers to antineutrophil cytoplasmic antibodies - autoantibodies directed against components of neutrophil granules.

Anti-citrullinated vimentin antibodies: what the test shows and how to interpret the results

Anti-citrullinated vimentin antibodies belong to a family of autoantibodies against citrullinated proteins.

Pancreatic beta cell antibodies: what the test shows, how it's interpreted, and when it indicates early type 1 diabetes

When people talk about antibodies to pancreatic beta cells in everyday life or in clinical practice, they usually mean not just one test, but a group of islet autoantibodies directed against the antigens of insulin-producing cells.

Antibodies to beta-2-glycoprotein 1: What the test shows and how to interpret the results

Antibodies to beta-2-glycoprotein 1 are autoantibodies, meaning they are antibodies against the body's own structures. In this case, the target is beta-2-glycoprotein 1, a plasma protein associated with phospholipid-binding complexes.

Antibodies to Castle's intrinsic factor: what the test shows, how it is interpreted, and when it confirms autoimmune gastritis

Intrinsic factor is a protein produced by the parietal cells of the stomach and is needed for the absorption of vitamin B12 in the terminal ileum.

Antibodies to double-stranded deoxyribonucleic acid: the significance of the analysis, interpretation and clinical role

Anti-dsDNA antibodies are autoantibodies, which are immune system proteins that mistakenly target the body's own genetic makeup.

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