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Antibodies to myeloperoxidase of neutrophils in the blood
Last reviewed: 23.04.2024
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In the norm antibodies to myeloperoxidase neutrophils in serum are absent.
Myeloperoxidase is a protein with a molecular weight of 59,000, which is one of the main factors that ensure bactericidal protection of a person. Antibodies to myeloperoxidase neutrophils may appear in vasculitis (microscopic polyangiitis - in 60-65% of cases, Cherdja Strauss - in 17-20%), rheumatoid arthritis, systemic lupus erythematosus, Goodpasture's syndrome.
The frequency of detection of various types of antibodies in vasculitis
|
Frequency of detection of AT,% | |||
|
Type AT |
Wegener's granulomatosis |
Microscopic polyangiitis |
Czurdzha Strauss Syndrome |
| ANCA | 85-95 | 75-95 | 65-75 |
| AT to protein kinase-3 | 75-80 | 25-35 | 10-15 |
|
Anti-MP |
10-15 |
50-60 |
55-60 |
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