Antibodies to myeloperoxidase of neutrophils in the blood
Last reviewed: 23.04.2024
All iLive content is medically reviewed or fact checked to ensure as much factual accuracy as possible.
We have strict sourcing guidelines and only link to reputable media sites, academic research institutions and, whenever possible, medically peer reviewed studies. Note that the numbers in parentheses ([1], [2], etc.) are clickable links to these studies.
If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please select it and press Ctrl + Enter.
In the norm antibodies to myeloperoxidase neutrophils in serum are absent.
Myeloperoxidase is a protein with a molecular weight of 59,000, which is one of the main factors that ensure bactericidal protection of a person. Antibodies to myeloperoxidase neutrophils may appear in vasculitis (microscopic polyangiitis - in 60-65% of cases, Cherdja Strauss - in 17-20%), rheumatoid arthritis, systemic lupus erythematosus, Goodpasture's syndrome.
The frequency of detection of various types of antibodies in vasculitis
|
Frequency of detection of AT,% | |||
|
Type AT |
Wegener's granulomatosis |
Microscopic polyangiitis |
Czurdzha Strauss Syndrome |
| ANCA | 85-95 | 75-95 | 65-75 |
| AT to protein kinase-3 | 75-80 | 25-35 | 10-15 |
|
Anti-MP |
10-15 |
50-60 |
55-60 |
[