Investigation of enzymes and isoenzymes

Learn how enzymes and isozymes testing is performed, how to prepare, and how to interpret results together with a clinician.

Liver function tests during pregnancy: interpretation features

Both during pregnancy planning and during pregnancy, a woman regularly undergoes a series of laboratory tests to assess her overall health and promptly identify any pathological changes.

Liver function tests: what is included in the analysis?

A liver function test is a screening test aimed at assessing the functional state of the biliary system and liver. Diagnosis is made using a blood sample.

Liver function tests in children: why they are prescribed and the norm

Tests are selected based on the baby's age, growth and hormonal characteristics, the presence of congenital anomalies and chronic diseases.

Liver function tests: preparation and how to take the test

The liver is the largest gland in the human body. It occupies the upper right section of the abdominal cavity, located beneath the diaphragm.

LDH-1: isoenzyme and its importance for the heart

Lactate dehydrogenase isoenzymes are present in tissues in a strictly defined ratio, that is, each tissue, including blood, has a characteristic spectrum of lactate dehydrogenase isoenzymes unique to it.

Troponin I: laboratory diagnostics of myocardial infarction

Troponin I is a structural protein of the muscle troponin complex with a molecular weight of 26,500 Da. Troponins I, like troponins T, of cardiac and skeletal muscles differ significantly in their amino acid sequence.

Troponin T: A key test for suspected heart attack

The troponin complex is part of the muscle contractile system. It is formed by three proteins: troponin T, which binds to tropomyosin (molecular weight 3,700); troponin I (molecular weight 26,500), which can inhibit ATPase activity; and troponin C (molecular weight 18,000), which has a significant affinity for Ca2+.

Myoglobin: An early marker of muscle damage

Myoglobin is a heme-containing chromoprotein; it is a light chain of myosin with a molecular weight of 17.6 kDa. It is a protein that transports oxygen in skeletal muscle and myocardium.

Creatine kinase MB: an enzymatic marker of cardiac damage

Creatine kinase in cardiac muscle consists of two isoenzymes: CK-MM (60% of total activity) and CK-MB (40% of total activity). CK-MB is a dimer consisting of two subunits: M (muscle) and B (brain).

Total creatine kinase: muscle damage and diagnosis

Creatine kinase reversibly catalyzes the phosphorylation of creatine. Creatine kinase is most abundant in skeletal muscle and cardiac muscle, while it is found in smaller amounts in the brain, thyroid gland, uterus, and lungs.

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