The most important plasma protein is albumin, solutions of which are widely used in surgical practice. Experience shows that the use of albumin solutions is the "gold standard" for transfusion therapy of critical conditions caused by hypovolemia and intoxication.
For quite a long time, preserved donor blood was considered to be the most effective and universal means of treating hemorrhagic anemias, hypovolemic conditions, disorders of protein metabolism of various etiologies, etc.
Erythrocyte mass (EM) is a component of blood, which consists of erythrocytes (70-80%) and plasma (20-30%) with an admixture of white blood cells and platelets (hematocrit - 65-80%). According to the erythrocyte content, a single dose of erythrocyte mass (270 ± 20 ml) is equivalent to one dose (510 ml) of blood.
Therapeutic hemapheresis includes plasmapheresis and cytarapheresis, which are usually tolerant for healthy donors. However, there are many small and somewhat significant risks.
Before beginning the transfusion, it is necessary to check the labeling of the container, carry out compatibility tests to ensure that the component is intended for the recipient.
Transfusion of whole blood improves oxygen capacity of blood, volume recovery, coagulation factors and was previously recommended for massive blood loss.
More than 23 million doses of blood components per year are poured into the United States. Despite the fact that at present the procedure of blood transfusion is much safer than before, the risk (and public perception of risk) requires the patient's informed consent to blood transfusion in all cases.
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