Hepatic tests during pregnancy

Both at the stage of pregnancy planning and during the gestation of a child, the woman regularly gives a set of laboratory tests to assess the general condition of the body and timely detection of any pathological changes.

Hepatic tests in pregnancy consist of many different indicators, but special attention is paid to ALT and AST. The change in the values of these enzymes indicates not only liver damage, but also detoxification of the mother and fetus.

• AST in the first trimester - up to 31 U / l. In the second and third trimester - 30 U / l.
• ALT in the first trimester - up to 32 U / l. In the second and third trimester - up to 30 units / liter.

These indicators are averaged and can vary depending on the equipment of the diagnostic department, that is, the laboratory. If enzymes during pregnancy exceed the normal values, then as a rule, this is not a cause for concern. During embroidering, transient jumps are allowed due to hormonal changes in the body and the effect of the fetus on the woman's liver.

If the increased baked samples are accompanied by a painful symptomatology, then a comprehensive screening diagnosis of the liver is performed. An increase in the level of transaminases indicates cytolysis, that is, the death of the cells of the organ. This condition is typical for such diseases:

• Viral defeat.
• Inflammation of the gallbladder.
• Autoimmune hepatitis.
• Cirrhosis of the liver.
• Medicinal hepatitis.
• Fatty degeneration of the liver.
• Yellow atrophy of the liver in the first trimester.
• Preeclampsia (late toxicosis).

The above conditions require additional diagnosis and medical correction. For treatment use the most gentle methods, so as not to harm the mother and the future child.

[1], [2], [3], [4], [5], [6], [7], [8]

Preparation

In order for the analysis on liver tests to be as reliable as possible, it is necessary to properly prepare for its passage. One week before the study, you should stop taking medication and go on a diet. Blood sampling is performed on an empty stomach, the last meal should be 8-12 hours before screening.

The norm of hepatic tests in pregnancy

Index	I trimester	II trimester	III trimester
Bilirubin μmol / l:
General information	3.4-21.6	3.4-21.6	3.4-21.6
Straight	0-7.9	0-7.9	0-7.9
Indirect	3.4-13.7	3.4-13.7	3.4-13.7
ALT, ED / L	Up to 32	Up to 31	Up to 31
ADT, IT / L	Up to 31	Up to 30	Up to 30
GGT, ED / l	Up to 36	Up to 36	Up to 36
Alkaline phosphatase, ED / L	40-150	40-190	40-240

 

Let's consider in more detail the main indicators of the liver during pregnancy:

1. Bilirubin - during the period of gestation it is possible to increase indirect bilirubin at normal values of ALT, AST, GGT and a number of other parameters. This condition is called Gilbert syndrome and refers to congenital pathologies that persist throughout life, but do not pose a danger to the mother and child.
2. ALT - an increase in this enzyme is possible with late gestosis during pregnancy.
3. AST - minor fluctuations are possible in the first and second trimester. If high rates persist throughout the entire pregnancy, then this indicates a disruption in the liver.
4. GGTP - increases in the second trimester, as well as in diseases of the liver and bile excretion system, diabetes mellitus.
5. Alkaline phosphatase - the increase occurs in the second and third trimester because of the active growth of the fetal bone tissue. Also, a violation of the level of alkaline phosphatase may indicate a disease of the bone system of the mother, hepatic cholestasis, hepatitis.

Hepatic tests in pregnancy

During pregnancy, the female body undergoes hormonal changes. This negatively affects the condition of internal organs, which experience increased load. Particular attention is paid to the liver. To assess the functionality of the body, a woman gives up venous blood for analysis. The biological fluid is examined for hepatic assays: ALT, AST, GGT, bilirubin, APF.

Many women have an excess of the norm of liver tests. In most cases, transient jumps are caused by hormonal reorganization and do not threaten future mother and fetus.