Treatment of acute cystitis with drugs

Most often the inflammation of the bladder proceeds in a chronic form, periodically exacerbating. To date, there are many medications used to treat cystitis of various etiologies.

The main groups of drugs in the treatment of acute cystitis

1. Since the disease has a bacterial nature, the basis for treatment is broad-spectrum antibiotics. They have many contraindications and side reactions, so they can only be used for medical purposes.

• Flaprox

Antibacterial agent for systemic use with an active component of ciprofloxacin. It is used for inflammatory diseases of the pelvic organs, genitourinary system. Effective in infections of the lower respiratory tract caused by gram-negative microorganisms. Infections of the gastrointestinal tract, bones and joints, neutropenia. With uncomplicated cystitis take 250 mg twice a day for three days.

• Levoximed

Synthesized antibiotic from the group of fluoroquinolones. Contains the active ingredient - levofloxacin 500 mg / 100 ml. Affects the DNA of bacterial cells of Gram-positive and Gram-negative microorganisms. It is used for chronic and acute inflammatory and infectious processes in the organs of the genitourinary system, pneumonia, lesions of the prostate gland, soft tissues. Dosage depends on the severity of the disease state. On average, the daily dose is 500 mg divided into two doses. Duration of treatment is from 7 to 14 days.

• Fazazolidon

Antibacterial drug of the group of nitrofurans. Contains active ingredient - furazolidone 500 mg. Has a pronounced antimicrobial activity against gram-negative aerobic microorganisms and to a lesser extent to gram-positive aerobes. Low doses have a bacteriostatic effect, and an increased dosage has a bactericidal effect.

It is used for the treatment of infectious diseases of the organs of the genitourinary system, gastrointestinal tract, skin. Also used for food intoxication. The drug takes 2-3 capsules 3-4 times a day. The duration of therapy is determined by the attending physician.

List of antibiotics used in the treatment of acute cystitis read in this article

Another group of medicines is phytopreparations, that is, herbal remedies. In acute forms of inflammation of the bladder, they are often used as an aid for complex therapy.

• Tsunami

Biologically active additive, whose action is aimed at improving the functions of the urinary system. Prevents the spread of pathogenic agents in the urinary tract. It is used for the prevention of bacterial cystitis, nonspecific urethritis, urinary tract infections with surgical and diagnostic manipulations. Supplements take 1-2 capsules 2-3 times a day in 20 minutes after eating. Duration of treatment is from 3 to 4 weeks.

• Urolean

Herbal remedies with a combined composition. It has antiseptic properties, increases diuresis, improves renal blood flow, increases bile formation and bile secretion. It is used for concrements in the urinary and gallbladder, kidney diseases, cholecystitis, dyskinesia. Uroleans take 2-3 times a day, dripping 5-10 drops per piece of sugar. With pain in the urine and bladder, the dosage is increased to 15-20 drops.

• Phytolite

The drug is plant-based. Contains extract of hawthorn, sporis, St. John's wort, horsetail and avisana. Has spasmolytic, diuretic, analgesic and anti-inflammatory properties. Normalizes mineral metabolism, exhibits antimicrobial and antiseptic activity. It is used for urolithiasis, in the complex therapy of chronic inflammatory diseases of the urinary tract. The drug takes 2-3 capsules before meals three times a day. Duration of treatment is 20-30 days.

3. The third group of medicines is analgesics and antispasmodics for relief of painful sensations.

• Ibuklin

Combined drug with analgesic, anti-inflammatory and antipyretic properties. It is used for rheumatic diseases, traumatic lesions of soft tissues. Pain in the organs of the genitourinary system, the spine, as well as with myalgia, toothache, infectious and inflammatory diseases of the upper respiratory tract. The medicine is taken 1 tablet 2-3 times a day. The duration of therapy depends on the severity of the pathological condition.

• Diclofenac

Nonsteroidal anti-inflammatory drug with active ingredient - diclofenac sodium 25 mg. Has a pronounced anti-inflammatory, analgesic and moderate antipyretic properties. It is used for pain syndrome of various etiology, moderate and moderate intensity. The medication is administered intramuscularly by 75 mg 1-2 times a day, the course of treatment is 4-5 days.

• Fanigan

Anesthetic with paracetamol 500 mg and diclofenac sodium 50 mg. Has analgesic, anti-inflammatory and antipyretic effect. It is used for pain syndrome of various origin and severity. With cystitis take 2-3 tablets per day. The duration of treatment should not exceed 5-7 days.

4. Probiotics are also used for treatment. Their action is aimed at restoring a healthy microflora of the intestine and vagina.

• Acipol

Probiotic is a lyophilized mixture of live lactobacilli and kefir fungi. Has antimicrobial activity against pathogens that provoke infectious gastrointestinal infections. It is used to restore the intestinal microflora after a long reception of antibiotics, with acute intestinal infections, dysbiosis, food disorders.

• Probifer

Bifidobacteria, improving the digestive process. It has antidiarrheal action, normalizes intestinal microflora. Has immunomodulatory properties. Has an antagonistic effect against pathogenic flora of the intestine. Accelerates the implementation of the anti-infective action of other medicines. The medicine is taken orally, the dosage and duration of therapy is determined by the doctor.

• Bifiform

Normalizes the intestinal microflora, is used to treat and prevent dysbiosis, diarrhea, conditions after prolonged antibacterial therapy. The medicine is taken 2-4 capsules per day.

Anesthetics for acute cystitis

Acute inflammatory process in the bladder causes severe pain in the lower abdomen, burning, itching, frequent urge to urinate. In some cases, the painful symptoms are so severe that the patient has to adhere to bed rest.

Painful syndrome with acute cystitis occurs due to such factors:

• Infection - bacterial, viral pathogens cause edema of the bladder tissue, the formation of erosion on the mucous membranes, urine irritation.
• Spasms of smooth muscles of the bladder - an inflammatory process causes a contraction of muscle tissue, which leads to a violation of blood circulation and a difficult flow of urine. Pronounced stagnation increases discomfort and pain.

Anesthetic drugs are used to eliminate acute pain. In acute cystitis, most commonly used are:

1. Aspirin

The combined drug with the active component is acetylsalicylic acid. Possesses analgesic, antipyretic and anti-inflammatory properties.

• Indications for use: pain syndrome of mild and moderate intensity of various origin. Inflammatory processes in the genitourinary system, headache and toothache, algodismenorea. Feverish conditions, thrombophlebitis, thrombosis, cerebral circulation disorders, ischemia.
• Usage: oral 1-2 tablets per day, the maximum daily dose - 8 capsules. The duration of treatment depends on the severity of pain.
• Side effects: allergic reactions, itching, urticaria, edema of the nasal mucosa. In rare cases, reactions from the gastrointestinal tract develop: nausea, vomiting, bleeding, thrombocytopenia.
• Contraindications: pathological tendency to bleeding, asthma, hypersensitivity to salicylates, deficiency of glucose-6-phosphate dehydrogenase, diseases of the digestive tract, impaired renal function, last trimester of pregnancy.
• Overdose: nausea, vomiting, epigastric pain, dizziness and headaches, decreased visual acuity and hearing, drowsiness, shortness of breath. Treatment is symptomatic with gastric lavage.

Form release: tablets and soluble capsules of 10 pieces in a blister.

2. The perfected

Spasmolytic and analgesic. It is used for spasms of smooth muscles, bladder tenesmus, renal / hepatic colic. Effective with spasms of the gastrointestinal tract and spasmodic dysmenorrhea. The medicine is taken 1-2 tablets 3 times a day, in especially severe cases, intramuscular / intravenous administration of the drug is indicated.

Baralgin is contraindicated in granulocytopenia, tachyarrhythmia, increased intraocular pressure, coronary artery insufficiency, prostatic hypertrophy. Adverse reactions are manifested by allergic rashes, pruritus, granulocytopenia and require withdrawal of the drug. Produced in the form of tablets of 20 pieces per pack and in ampoules of 5 ml of 5 pieces per pack.

3. Ketanov

Contains the active ingredient - ketorolac, which has analgesic and anti-inflammatory effect. The active substance inhibits the aggregation of platelets, caused by arachidonic acid and collagen. Does not affect ATP-induced platelet aggregation.

• Indications for use: a short treatment for relief of moderate and severe pain of various etiologies. The medication is effective in the acute form of cystitis, toothache, kidney and liver colic, sprains, dislocations, fractures, migraine, radiculitis, oncological pain.
• The way of application and dosage depends on the form of release of an anesthetic. Intramuscularly injected 10 mg, followed by a dose of 10-30 mg every 4-6 hours. The maximum daily intake for adults is 90 mg. Tablets are taken orally 1 capsule every 4-6 hours. The duration of treatment should not exceed 7 days.
• Side effects: nausea, vomiting, constipation, diarrhea, indigestion, abdominal pain, increased drowsiness, headaches and dizziness, myalgia, palpitations. With intramuscular injections, local reactions and pain sensations are possible.
• Contraindications: intolerance of the drug components, pregnancy and lactation, birth process, patients younger than 16 years, bronchial asthma, peptic ulcer of the digestive tract, disorders of the blood coagulation system, renal failure, angioedema.
• Overdose: nausea, vomiting, deterioration in overall well-being, diarrhea, shortness of breath, pale skin. There is no specific antidote, treatment is symptomatic.

Product: tablets of 10 pieces in a blister, 1, 2, 10 blisters in a package. Ampoules of 10 pieces per pack.

4. Friend

Anesthetic, anti-inflammatory, antipyretic and antiplatelet agent. Suppresses the process of prostaglandin formation in the inflammatory focus, selectively inhibits COX2. When oral administration is well absorbed from the digestive tract, the maximum concentration is achieved after 1-2.5 hours. The elimination half-life is about 3 hours. It is excreted by the kidneys.

• Indications for use: inflammatory and infectious diseases of various origin, including lesions of the genitourinary system. Neuralgia, osteoarthritis, osteoarthritis, bursitis, rheumatism, muscle pain, posttraumatic pain syndrome.
• Method of administration: tablets are taken orally in 100 mg divided into two doses. The maximum daily dose is 400 mg. The gel is applied a thin layer on the lesion sites 3-4 times a day. The duration of treatment should not exceed 10 days.
• Side effects: headaches, drowsiness, dizziness, nausea and vomiting, pain and ulceration of the gastrointestinal mucosa, fluid retention in the body, leukopenia, various allergic reactions.
• Contraindications: hypersensitivity to the components of the drug, gastrointestinal ulcer in the acute stage, hepatic / renal failure, congestive heart failure. It is not used to treat patients with type 2 diabetes mellitus, during pregnancy and lactation, with hypertension, for children under 12 years.
• Overdose: irritation of the gastrointestinal tract, convulsions, hepatic insufficiency, impaired renal function, respiratory depression, high blood pressure. For treatment, the drug cancellation, gastric lavage and reception of enterosorbents with further symptomatic therapy are indicated. Hemodialysis and forced diuresis are ineffective.

Product: tablets of 100 mg, dispersible tablets of 50 mg, suspension for ingestion 50 mg / 5 ml, gel for external application of 1%.

5. Pentalgin

Combined analgesic, anti-inflammatory and antipyretic drug. Contains 5 active ingredients, which cause a rapid and effective therapeutic effect: paracetamol, metamizole sodium, phenobarbital, codeine and caffeine.

• Indications: acute pain syndrome of different localization. Arthralgia, myalgia, neuralgia, toothache, migraine. Symptomatic therapy for acute respiratory viral infections and influenza for elimination of fever, muscle weakness and inflammatory reactions.
• Method of administration: 1 tablet per os with acute non-acute pain syndrome, 1-3 tablets with prolonged pain. The maximum daily dose is 4 tablets. The duration of therapy is determined by the attending physician, individually for each patient, but not more than 7 days.
• Side effects: nausea, vomiting, pain in the epigastric region, a violation of appetite and digestion. Increased fatigue, disturbance of sleep and wakefulness, increased anxiety. Also, there are possible violations of the cardiovascular system and sensory organs. Some patients report allergic reactions. With prolonged use, the drug cancellation syndrome is possible.
• Contraindications: hypersensitivity to the components of the drug, severe kidney / liver damage, erosive and ulcerative diseases of the digestive system, impaired function of the hematopoiesis system, myocardial infarction, arrhythmia, arterial hypertension. Not applicable to patients under 12 years of age, during pregnancy and lactation.
• Overdose: nausea, vomiting, heart rhythm disturbance, allergic reactions, hypotension, pallor of the skin, pain in the epigastric region. Treatment is symptomatic with gastric lavage and intake of enterosorbents.

The form of release: tablets on 10 and 12 pieces in a blister, on 1 blister in packing.

[1], [2], [3], [4], [5]

Suppositories for acute cystitis

Another type of medicines used in acute inflammation of the bladder are candles. Patients can be assigned both rectal and vaginal suppositories in combination with oral agents, injections, physiotherapy procedures

To eliminate pathological processes and prevent various complications from the urogenital system, the following types of candles are used:

• Antibacterial - contain special components that disrupt the functioning and destroy cells of pathogenic microorganisms. Such drugs reduce the impact of infection on the genitourinary system and destroy pathogens.
• Anti-inflammatory - effectively combat the inflammatory process, anesthetize, speed up the healing process.
• Spasmolytic - aimed at arresting spasms in the tissues of the smooth muscles of the bladder. Suppositories relieve pain and restore the process of blood supply to the affected organ.
• Hematogenic - improve blood supply in the bladder, speeding up the recovery process. Most often, they use plant-based drugs that effectively strengthen the walls of small blood vessels.

For the treatment of acute forms of cystitis, such suppositories can be prescribed:

1. Betadine

Antimicrobial and antiseptic with active ingredient is a complex compound of iodine with polyvinylpyrrolidone. It has bactericidal, antifungal, antiviral and antiprotozoal effects. It is active against gram-positive and gram-negative pathogens.

• Indications for use: vaginitis, candidiasis, trichomoniasis. With cystitis, Betadine reduces pain during urination and discomfort in the abdomen.
• How to use: before use, the suppository is moistened with water and injected deeply into the vagina. In severe conditions, 1-2 candles per day are prescribed. The course of treatment is 5-7 days.
• Side effects: local allergic reactions. With prolonged use, generalized reactions are possible: metabolic acidosis, abnormalities on the part of the blood system, impaired renal function, anaphylactic reactions. For treatment, the withdrawal of the drug is indicated.
• Contraindications: hypersensitivity to the components of the drug, pregnancy and lactation, patients younger than 1 year, hyperthyroidism, renal / hepatic insufficiency, thyroid adenoma, herpetiform dermatitis of Dühring.
• Overdose: pain in the epigastric region, nausea and vomiting, collapse, increased salivation, acute renal failure, tachycardia, hypertension. As an antidote recommended solution of milk with starch and further medical assistance.

Form release: suppositories vaginal in a package of 14 pieces, solution for external use 10% of 100 ml in a vial.

2. Voltaren

Anti-inflammatory, analgesic and antipyretic agents from the pharmacological group of NSAIDs, inhibitors of cyclooxygenase. Contains the active ingredient - diclofenac.

• Indications for use: pain syndrome in the organs of the genitourinary system, swelling of soft tissues and joints, pain in the spine, osteoarthritis, gout, primary dysmenorrhea and other gynecological diseases with pain and inflammatory processes.
• Method of administration: suppositories are administered rectally at 100-150 mg per day, divided into 2-3 doses. The duration of treatment depends on the severity of the disease state and is determined by the attending physician.
• Side effects: the suppository can cause only local allergic reactions. Other forms of the drug are capable of provoking disorders of the gastrointestinal tract, hypertension, dizziness and headaches, increased fatigue, edema, nephrotic syndrome and others.
• Contraindications: hypersensitivity to the components of the drug, third trimester of pregnancy, patients younger than 6 years. Violations of the hematopoiesis system, severe pathology of the kidneys, liver, cardiovascular system, hemorrhoids.
• Overdose: nausea, vomiting, pain in the epigastric region, convulsive condition. For treatment, gastric lavage, reception of enterosorbents and further symptomatic therapy are indicated.

The form of release: suppositories rectal for 25, 50 and 100 mg on 5 pieces in a blister, on 2 blisters in packing. Also, the drug is available in the form of oral tablets and a solution for intramuscular injection.

3. Hexicon

The drug with the active ingredient is chlorhexidine bigluconate. Has an antiseptic effect against gram-positive, gram-negative bacteria and protozoa. The therapeutic effect comes very quickly, since the active substance acts directly on the inflammation focus.

• Indications for use: preventive treatment of gynecological and urological diseases. It is used in obstetrics before delivery, abortion, surgical interventions on pelvic organs. Treatment of acute and chronic vaginitis. Prophylaxis of ureaplasmosis, trichomoniasis, gonorrhea and other sexually transmitted infections.
• Method of application: the drug is injected into the vagina for 1 suppository 1-2 times a day. The course of treatment is 7-10 days. If necessary, repeat therapy is performed after 20 days.
• Side effects: itching in the genital area and other local allergic reactions. Discomfort occurs after the drug is discontinued. There have been no cases of overdose.
• Contraindications: allergic reactions to the components of the drug. Use during pregnancy and lactation is permitted.

Form release: suppository for intravaginal application for 1, 5, 10 pieces per package. Each suppository contains 16 mg of chlorhexidine bigluconate.

4. Mcmiror

Vaginal suppositories with a combination of active ingredients: nifuratel and nystatin. It has pronounced antimicrobial, fungicidal and antiprotozoal properties.

• Indications for use: bacterial infections of urogenital localization, urogenital trichomoniasis, vaginal candidiasis, topical treatment of chlamydial infections. Infections caused by microorganisms that are sensitive to the drug.
• Method of application: the drug is injected deep into the vagina, 1 candle a day before bedtime. Duration of treatment is 5-8 days.
• Side effects: allergic reactions, local itching, rashes.
• Contraindications: intolerance to the components of the drug. The use during pregnancy and lactation is possible according to the prescription of the attending physician.

The form of release: vaginal suppositories on 8, 12 pieces in a blister, on 1 blister in packing.

5. papaverine

Drug with active ingredient - papaverine hydrochloride, 20 mg per suppository. Refers to myotropic antispasmodics. Suppresses the synthesis of phosphodiesterase, relaxes the smooth muscles of internal organs and vessels.

• Indications for use: spasm of smooth muscles of the urogenital system and abdominal cavity, vessels of the brain, heart, bronchi.
• Contraindications: hypersensitivity to the components of the drug, elderly patients, glaucoma, severe hepatic insufficiency, respiratory depression, blockade.
• Method of application: suppositories are used after cleansing enema or bowel movement, introducing deep into the anus. For patients older than 14 years, appoint 1 candle 2-3 times a day. The duration of treatment is determined by the attending physician.
• Side effects: allergic reactions at the injection site, eosinophilia, arterial hypotension, drowsiness, weakness, headaches, excessive sweating, stools. Overdose has similar symptoms. There is no specific antidote, treatment is symptomatic with withdrawal of the drug.

Product: suppository for 5 pieces in a blister, 2 blisters per package.

The main advantage of suppositories is that their active components are rapidly absorbed by the walls of inflamed tissues, providing a therapeutic effect directly on the lesion site. The active substances of suppositories do not penetrate into the systemic blood flow and the organs of the digestive tract. One of the drawbacks of preparations of this form of release is the risk of irritation of the mucous membranes.