Suppositories for cystitis in women: rectal, vaginal

In the structure of the pathology, cystitis is almost in the first place. Therefore,  suppositories from cystitis are widely used.

With cystitis in women, suppositories are prescribed. They can be used both rectally and intravaginally. It is preferable to use vaginal suppositories, since they are most effective in combating the infection that causes the development of cystitis. Consider the main candles prescribed for cystitis in women.

• Tool #1. Terzhinan - vaginal tablets that have an antiseptic, antifungal effect. Active ingredients: ternidazole, neomycin, nystatin, prednisolone. In addition to affecting the fungal and bacterial microflora, the active substances are active against trichomonads, gardnerella, representatives of anaerobic microflora. When analyzing the pharmacological group, it is noted that the drug belongs to the group of aminoglycosides.

The advantage of the drug is that it has a pronounced effect even with a high degree of contamination. Resistance to it is developed rather slowly.

Terzhinan is administered intravaginally, one tablet once a day. The average duration of treatment is 10 days. If the drug is prescribed for prophylactic purposes, the duration of treatment is 5-7 days. Side effects are rare. Sometimes there are reactions such as itching, burning, irritation, increased inflammation, allergic reaction. There are not many contraindications. The drug is contraindicated only in case of individual intolerance to the components that make up its composition. The drug can be used in the second trimester of pregnancy. For the period of menstruation, treatment continues.

• Tool number 2. Polygynax - vaginal capsules. It is prescribed for cystitis, other bacterial, fungal, inflammatory diseases of the reproductive organs and the genitourinary system. Active ingredients - neomycin, nystatin, polymyxin. It has a bactericidal effect against gram-positive and gram-negative microflora, has fungicidal properties, stops the growth of yeast-like fungi. The drug is prescribed topically, 1-2 doses per day. Intensive absorption from the surface of the mucous membrane does not occur. Therefore, the drug can be used during pregnancy, before childbirth, operations, for the sanitation of the reproductive organs, genital tract. As for contraindications, these include cases of individual intolerance to the drug, hypersensitivity, allergic reactions, irritation, contact eczema.
• Tool number 3. Voltaren in the form of suppositories is prescribed for cystitis, inflammatory diseases of the genitourinary tract, reproductive system. The main active ingredient is diclofenac. In most cases, it is recommended to use the drug intravaginally, since in the form of rectal suppositories the drug can cause numerous side effects, in particular, it can cause irritation, burning, swelling, erosion, inflammation. It is also worth noting a pronounced analgesic effect, reducing pain. Traditionally, 1-2 suppositories are administered per day. The duration of treatment is 5-7 days.
• Tool number 4. Ichthyol suppositories are an effective anti-inflammatory agent. They are used for the treatment of cystitis, gynecological diseases, for the treatment of reproductive pathologies. This tool can be used even during pregnancy and lactation. Virtually no contraindications. Quickly eliminates inflammatory processes, stops the infectious process.

It is better for women to use the suppository intravaginally, however, rectal administration of the drug is also possible. A maximum of three candles per day is allowed. The course of treatment averages 10 days.

• Tool number 5. Chlorhexidine is used to treat infectious diseases of bacterial and fungal infections, to relieve the inflammatory and infectious process, in acute and chronic cystitis. Chlorhexidine is effective against herpesvirus infection, chlamydial infection, trichomoniasis, ureaplasmosis, treponema pallidum, and a number of sexually transmitted infections. It is used in surgical pathologies, for the rehabilitation of the reproductive tract before childbirth and surgical procedures, abortions.

How to use: the suppository is inserted deep into the vagina. It is necessary to administer the drug twice a day, the course of treatment is approximately 15-20 days. The drug is not recommended to be combined with other suppositories.

• Tool number 6. Pimafucin suppositories are used to treat cystitis of various origins, to treat and prevent bacterial and viral infections. The composition includes natamycin (a substance of antifungal and antibacterial effects). The drug belongs to the group of macrolides. It is worth noting the broad antifungal action.

The drug is indicated for intravaginal treatment. A single dosage is 100 mg, that is, one suppository. Multiplicity of reception - 1-2 times a day. Duration - 3-7 days. The drug is not used during menstruation, or is administered rectally.

• Tool number 7. Suppositories with belladonna are used mainly in the form of rectal suppositories, less often - intravaginally. The main active ingredient is belladonna extract (a herbal remedy). The drug has a relaxing effect on the muscles of the urogenital tract and has practically no effect on the mucous membranes, on the circulatory system, microcirculation. The method of application of the drug is determined strictly individually.
• Tool number 8. Clotrimazole is a drug that is used in the form of suppositories for the treatment of thrush, cystitis, and other inflammatory and infectious pathologies. Suppositories are indicated for the treatment and prevention of sexually transmitted pathologies, fungal infections. The tool is effective in the treatment of acute, chronic cystitis.

Clotrimazole is available as vaginal tablets. The main active ingredient is clotrimazole (an antifungal agent). Tablets should be taken several times a day. To achieve a sustainable effect, it is necessary to be treated with a course of at least 5-7 days. The suppository is introduced intravaginally, while it is necessary to administer the suppository in the supine position, with legs apart, as deep as possible.

The drug is contraindicated in case of individual intolerance to drugs, with hypersensitivity. Also, you can not use the remedy during menstruation, during pregnancy. There are side effects: swelling, burning, itching at the injection site. Drug. As a rule, after course adjustment, side effects disappear.

• Tool number 9. Polyoxidonium suppositories can be used as vaginal or rectal suppositories. The main active ingredient is azoximer bromide. It is prescribed for local and generalized infections, allergies, immunodeficiencies. The mechanism of action is to simulate the synthesis of interferons, hormones. Prevents the development of inflammatory and infectious pathologies. It can be used both in the stage of remission and in the stage of exacerbation. It can be used to treat and prevent many diseases of the genitourinary system. It is recommended to use the drug once or twice a day.
• Tool number 10. For the treatment of cystitis, suppositories with palin are widely used. The main indication for use is signs of cystitis, abdominal pain, pain during urination, pain in the kidneys and lower back. Palin eliminates inflammation, normalizes microflora, destroys pathogenic microflora.

The main active ingredient is pipemidic acid. This is an antibacterial agent. The drug is prescribed 1-2 suppositories per day. The course of treatment ranges from 5-10 days.

Vaginal suppositories for cystitis

Vaginal suppositories for cystitis are prescribed to women suffering from acute or chronic cystitis.

Intravaginally prescribed: nystatitn, suppositories with belladonna, terzhinan, pallin, clotrimazole, pimafucin, and other suppositories.

• Tool #1. Nystatin is an effective antifungal agent. Belongs to the group of polyenes. The drug is active against fungi of the genus Candida. The duration of treatment is up to 14 days, 2-3 times a day.

Possible side effects: nausea, vomiting, diarrhea, skin rash, irritability. The drug is contraindicated in liver and kidney failure, stomach ulcers, ulcerative gastritis, drug intolerance. With the development of local irritation and allergies, during menstruation, the drug is contraindicated.

• Tool number 2. Macmirror - suppositories that have antimicrobial activity. The drug is active against gram-positive, gram-negative microflora, as well as against antifungal microflora. The drug is contraindicated during pregnancy and lactation. The main indications for the use of the drug are infectious and inflammatory diseases of the genitourinary tract, parasitic infections, chronic and acute pathologies. Side effects include nausea, vomiting, headache, and diarrhea. During treatment, you should refrain from sexual intercourse.
• Tool number 3. Polygynax is available in the form of vaginal capsules. It is prescribed for cystitis, other bacterial, fungal, inflammatory diseases. The drug has a mainly pronounced local effect, which allows you to quickly achieve high therapeutic effects. The drug is prescribed topically, 1-2 doses per day. It goes well with other medicines, including suppositories, tablets.
• Tool number 4. Pimafucin suppositories are used to treat cystitis of various origins, for their treatment and prevention.

A single dosage is 100 mg, that is, one suppository. Multiplicity of reception - 1-2 times a day. The duration of treatment is approximately 3-7 days.

• Tool number 5. Clotrimazole is a drug that is used in the form of suppositories to treat cystitis in women. The use of clotrimazole in the form of vaginal suppositories is the safest method of treatment. The drug is contraindicated in case of individual intolerance. The drug is intended for vaginal administration, respectively, is prescribed only for women.
• Tool number 6. Vaginal suppositories prescribed for women with cystitis - suppositories with belladonna. The main active ingredient is belladonna extract. In addition to relieving inflammation and eliminating the infectious process, it is worth noting that the drug has a relaxing effect on the muscles, thereby reducing pain.

Rectal suppositories for cystitis

Sometimes there is a need to use rectal suppositories. With cystitis, they are most often prescribed to men. However, often with a strong inflammatory process, they are also prescribed to women. There are suppositories that are used only rectally. Let's consider some of them.

Voltaren suppositories are prescribed for cystitis, inflammatory diseases of the genitourinary tract, cystitis. It is used both in the form of rectal and vaginal suppositories. Men are prescribed rectally, women - with moderate inflammation intravaginally, with severe inflammation - rectally. There are cases when suppositories are prescribed twice a day - rectally in the morning, intravaginally in the evening. This treatment regimen is used for long-term inflammation, progressive infection, and the absence of the effect of treatment. The main active ingredient is diclofenac. The drug has a pronounced anti-inflammatory, anti-infectious effect, is capable of relieving pain, reducing local and general temperature. It should be borne in mind that in the form of rectal suppositories, the drug can cause numerous side effects: irritation, burning, swelling, erosion, intensification and progression of inflammatory processes. Small bleeding, erosion, ulcers are possible, which requires immediate discontinuation of the drug.

The dosage and duration of treatment is determined by the doctor. But usually the drug is administered 1-2 suppositories per day. The duration of treatment is 5-7 days. At observance of the recommended dosage side effects are not observed. However, if there are signs of an overdose, discomfort, you should immediately inform the doctor, it may be necessary to revise the treatment regimen. The initial dose is 100-150 mg / day. Gradually, the dose may increase. It is not recommended to use the drug in patients under the age of 18 years. Also, funds are contraindicated in acute proctitis and rectitis. In case of overdose, supportive and symptomatic treatment is used. The drug is not combined with many drugs, and this must be taken into account.

Ichthyol suppositories are also often used to treat urological and gynecological diseases. It has practically no contraindications, is a relatively safe remedy, can be used even during pregnancy. The main indications for use are prostatitis, cystitis, salpingitis, colitis, vaginosis.

Suppositories are used mainly rectally. Before use, you need to carefully empty the intestines. It is necessary to use suppositories twice a day - in the morning and in the evening. It is best to use candles while lying down. The course of treatment averages 10 days. The drug is contraindicated in severe allergic reactions, with hypersensitivity. With bleeding wounds and cracks, it is also not recommended to use this remedy.

Chlorhexidine is prescribed for cystitis: it is effective for removing the inflammatory and infectious process, for acute and chronic cystitis. The method of application is quite simple: it is inserted deep into the vagina, or rectally. It is better for women to use intravaginally, for men it is prescribed rectally. In order to facilitate the introduction of the drug, it is necessary to lie on your back, slightly spread your legs. The drug is not recommended to be combined with other suppositories.

For the treatment of cystitis, belladonna suppositories are widely used. They are used in the form of rectal suppositories. This is a herbal remedy. The drug has a relaxing effect on the muscles of the urogenital tract. The drug has a number of side effects, for example, it can cause headache, nausea, vomiting, diarrhea, dry mucous membranes. The drug is contraindicated in pathologies of the gastrointestinal tract, proctitis, rectitis, pathologies of the prostate gland.

Polyoxidonium suppositories can be used as vaginal or rectal suppositories. The drug has a complex effect on the body. Can be used in children under 6 years of age. The drug is used for chronic and inflammatory diseases. It is used for fungal, viral, bacterial infections, microflora disorders. The drug is prescribed one suppository rectally or intravaginally. Entered once a day. The duration of treatment is 5-7 days.

Candles with palin are widely used  . They are often prescribed to treat cystitis. The main indication for use is signs of cystitis, abdominal pain, pain during urination, pain in the kidneys and lower back. The drug is prescribed 1-2 suppositories per day, depending on the severity of the pathological process, the severity of the pathology. The course of treatment ranges from 5-10 days. Can be used rectally or vaginally.

Diclovit is produced in the form of rectal suppositories. The mechanism of action is that it has anti-inflammatory, analgesic and antipyretic effects. It is used for inflammation, to stop the infectious process, to eliminate itching, irritation, swelling. With rectal administration, the maximum concentration of the drug in the blood is reached after 30 minutes. Adults are prescribed 1 suppository twice a day. The duration of treatment averages 5-7 days, depending on the severity of the pathological process. If the drug is ineffective, you can double the dosage - prescribe 100 mg of the drug per day (2 suppositories). The drug is contraindicated in erosive and ulcerative lesions in the gastrointestinal tract, with exacerbation of chronic diseases.

Synthomycin suppositories

With cystitis, synthomycin suppositories can be used. These are antibacterial suppositories. It is mainly used for diseases of the female reproductive system. The tool is convenient, easy to use, effective. The cost of the drug is relatively small. The main active ingredient is chloramphenicol, which has an antibacterial effect on the mucous membranes. The mechanism of action is to inhibit bacterial growth. Also, the drug prevents further reproduction of pathogenic microflora, normalizes normal microbiocenoses. The drug is active against a wide range of microorganisms: against staphylococcus, streptococcus, neisseria. It is used in gynecology (to prepare for surgical interventions, to sanitize the birth canal before childbirth. It is also worth noting that the drug has an antifungal effect.

It is prescribed only after consulting a doctor. Self-medication is strictly contraindicated. In many ways, the dosage and method of treatment depends on the severity of the pathological process, on the etiology of inflammation. Can be used prophylactically.

A distinctive feature is that the drug can be prescribed exclusively to women, since it is intended for intravaginal administration. Rectal use is not recommended, as numerous side effects are possible. Accordingly, the drug is not prescribed for men.

The method of application is described in detail in the instructions. Before use, be sure to read the instructions. First you need to thoroughly wash yourself, while using intimate hygiene products. Then the skin should be dried by blotting with a soft towel. Then you need to unpack the suppository by removing the protective shell from it. It is inserted deep into the vagina: with fingers, from a supine position. The legs need to be spread apart, which will allow the drug to be injected deeper. After the introduction of the drug, you need to lie down for some time (about 30-40 minutes). The introduction of 3-4 suppositories per day is allowed. The duration of treatment is 5-7 days. Side effects are mostly local: swelling, irritation, hyperemia, itching, burning. It is also possible inflammation in the mucous membranes. In case of an overdose, side effects from the digestive tract are possible: nausea, vomiting, indigestion, flatulence, diarrhea. With prolonged use and overdose, changes in the hematopoietic system are possible. In particular, the number of leukocytes, lymphocytes, platelets decreases sharply, the leukocyte formula changes.

Synthomycin suppositories may have side effects, such as allergic reactions, itching, swelling, redness. There are certain contraindications, for example, it is not recommended to use the drug for psoriasis, dermatitis, candidiasis. The drug is contraindicated in pregnancy, lactation, inflammatory and infectious diseases. Do not appoint children, adolescents. Assign without a prescription.

Acylact

The drug acylact is a vaginal suppository that is widely used to treat cystitis and other inflammatory and infectious diseases of the urinary system. The drug is prescribed to women. Inserted into the vagina, as deep as possible. Suppositories normalize natural microbiocenoses, since they contain predominantly acidophilic lactobacilli, which are normal representatives of the genitourinary tract of a woman and prevent the development of the inflammatory process. The mechanism of action is that the living bacteria that make up the drug have an antagonistic effect on other representatives of the microflora. Due to this, the activity of other microorganisms is inhibited. Free niches are filled with pathogenic microflora, including fungal, which leads to the development of an inflammatory and infectious process.

Acylact promotes the elimination of pathogenic microflora, and the filling of free niches with lactobacilli. In turn, lactobacilli not only prevent the reproduction of pathogenic microflora, but also contribute to the formation of a natural environment. Thus, bacteria synthesize the appropriate metabolites that contribute to maintaining normal pH, improve tissue trophism, and normalize metabolic processes. This contributes to the restoration of natural immunity, normalizes the specific resistance of the vaginal microflora. A characteristic feature is that lactobacilli contribute to the metabolism of glycogen, due to which lactic acid is formed, which maintains optimal parameters of the vaginal environment.

Often atsilact is prescribed for the prevention of cystitis, or after a course of antibiotic therapy, since it is he who contributes to the normalization of microflora, maintains the normal state of the mucous membranes. It can be used when the first signs of the disease appear. Eliminates dysbacteriosis. It is used for the treatment and prevention of the genitourinary system, venereal diseases. Due to the fact that the drug increases local immunity, supports the colonization resistance of the mucous membranes, it also has an effect against viral infection. It is used for acute, chronic and recurrent diseases.

One dose of the drug contains approximately 10 million live bacteria. One tablet is one dose. It is prescribed 1-2 doses per day. Intravaginally, acylact can be used not only in the form of suppositories, but also in the form of a spray intended for irrigation of the mucous membranes. Sometimes applications are used. With recurrent diseases, progression of the inflammatory and infectious process, the dosage can be increased to 5 doses per day. The duration of treatment averages 5-15 days. According to the indications, treatment can be continued until the complete disappearance of the clinical symptoms of the pathology. For control, the purity of the vaginal secretion is checked (scraping, smears, bacteriological cultures). Side effects are rare. Sometimes allergic reactions are observed. The drug is contraindicated in case of hypersensitivity to the components of the drug, with individual intolerance. Do not use the drug for candidiasis and other forms of fungal infection. It is not recommended to prescribe to children, during pregnancy and lactation, with immunodeficiencies. It is important that suppositories can be combined with other drugs, as well as with other suppositories. Can be used simultaneously with antibacterial, antiviral and antifungal agents. Enhances the effect of local immunomodulating agents.

Pharmacodynamics

Speaking about pharmacodynamics, it is worth noting that almost all suppositories used for cystitis have an antiseptic, antifungal effect. The composition includes mainly antiseptic, less often - anti-inflammatory drugs. Many drugs have analgesic, anti-inflammatory effect. Suppositories are classified as combined agents intended for local use. A characteristic feature of many suppositories is that it ensures the integrity of the mucous membrane, and also maintains a constant acidity in the vaginal environment. Some suppositories are aimed at influencing the fungal microflora (the effect is directed mainly against yeast-like fungi belonging to the genus Candida). Often suppositories have a bactericidal effect on gram-positive and gram-negative microflora. A characteristic feature is that in addition to the main antiseptic effect, suppositories have the ability to improve trophic processes, normalize metabolism, improve blood circulation and blood microcirculation. Suppositories have mainly a pronounced local effect, which allows you to quickly achieve high therapeutic effects. Suppositories are not absorbed into the systemic circulation. This avoids many side effects, contraindications.

The mechanism of action of suppositories is that intensive absorption from the surface of the mucous membrane does not occur. Therefore, many suppositories can be used during pregnancy, before childbirth, operations, for the sanitation of the reproductive organs, genital tract. Many rectal suppositories, in addition to the traditional anti-inflammatory and antiseptic effects, have a protective effect on prostatitis, strictures and injuries of the urethra and ureters. Therefore, rectal suppositories are recommended for use in acute and chronic interstitial cystitis, with its recurrence.

It is also worth noting the ability of many suppositories to relieve pain, to reduce temperature. The mechanism of action of such suppositories is that they significantly inhibit the synthesis of prostaglandins, which are directly involved in the development of inflammation, pain, and fever. Many suppositories allow you to quickly restore scars, scars, eliminate swelling and inflammation, and stop the infectious process.

Pharmacokinetics

When analyzing the pharmacokinetics, it was found that the components that make up the suppositories are quickly absorbed through the mucous membranes, slightly absorbed into the blood. That is, most suppositories have a local (local) effect, which allows them to be used to treat inflammatory processes in the genitourinary tract. The higher the dose, the more the drug is absorbed. In most suppositories, approximately 90-99% of the substances bind to plasma proteins. It is also worth noting that suppositories have the ability to penetrate liquids (blood, lymph, and other biological fluids), after about 3-4 hours. The concentration remains high up to 12 hours, so the use of many suppositories twice a day is justified. If the recommended dosage is observed, no side effects are observed, the cumulation of the substance in the tissues does not occur. Most of the drug is metabolized through the liver. It should also be borne in mind that some suppositories are found in small amounts in breast milk, which does not allow them to be used during pregnancy and lactation. There are suppositories that do not penetrate milk. Suppositories are indicated in the presence of inflammatory processes in the genitourinary system, in gynecological and degenerative diseases, in acute and chronic pathologies, in various forms of cystitis. It is recommended to use in severe pain syndrome, in preparation for surgery, in traumatic syndrome, in preparation for surgery and childbirth.

Use Candles for cystitis during pregnancy

With cystitis during pregnancy, not all candles can be used. Some of them have the ability to penetrate the transplacental barrier, and, accordingly, may have an effect on the fetus. This excludes the possibility of using such suppositories during pregnancy. If the active substances do not penetrate the transplacental barrier, but have only a local effect, they can be prescribed during pregnancy. In any case, suppositories can be used only after consulting a doctor. Consider the main suppositories used to treat cystitis.

So, terzhinan is often used. However, in the 3rd trimester, the drug is contraindicated, as it can cause insufficient cervical dilatation.

Ichthyol suppositories cause a minimum of side effects, have practically no contraindications. This tool can be used even during pregnancy and lactation.

Chlorhexidine may be prescribed during pregnancy. It acts within the mucous membrane, it is not absorbed into the blood. This allows the use of the drug during pregnancy and lactation. It is used in surgical pathologies, for the rehabilitation of the reproductive tract before childbirth and surgical procedures, abortions, in preparation for the introduction of an intrauterine device and other similar means.

Pimafucin is one of the few drugs approved for use during pregnancy. Pimafucin suppositories are used to treat cystitis of various origins, to treat and prevent bacterial and viral infections of the genital and reproductive tract.

For the treatment of cystitis during pregnancy, belladonna suppositories are widely used. The drug has practically no effect on the mucous membranes, on the circulatory system, microcirculation. In addition to acute and chronic cystitis, the drug is recommended for use in vaginosis, bacterial and viral infections, for the treatment and prevention of diseases of the reproductive tract. This remedy is indicated in preparation for surgical interventions, abortions, for sanitation of the birth canal before childbirth. The mode and method of application of this drug is determined in each case strictly individually. Therefore, before use, you need to consult a doctor. When applied topically, burning, irritation, and slight erosion are possible.

Clotrimazole is an effective means of combating bacterial and fungal infections. The use of clotrimazole in the form of suppositories is the safest method of treatment. This is due to the fact that clotrimazole in the form of suppositories practically does not penetrate into the systemic circulation, and therefore side effects are possible, or do not occur at all. Acts directly in the focus of inflammation. This allows the use of clotrimazole during pregnancy. Often, clotrimazole is prescribed to women for the treatment of vaginal pathologies, for the normalization of microflora, and the relief of the inflammatory and infectious process. Clotrimazole is prescribed for prophylactic purposes, for the treatment and relief of the inflammatory process, for the rehabilitation of the birth canal before childbirth, for preparation for operations, for the setting of an intrauterine device. However, the instructions indicate that it is not recommended to use in the first trimester of pregnancy. In the third trimester, the drug is contraindicated. In the second trimester, the drug should not be used, however, in case of emergency, the drug can be prescribed in the second trimester. It should be noted that the drug is administered intravaginally using a special applicator. However, during pregnancy, you need to administer the drug by hand, without using the applicator.

Polyoxidonium suppositories can be used as vaginal or rectal suppositories. It has an immunomodulatory, detoxifying, antioxidant, anti-inflammatory effect. Can be used during pregnancy, lactation. Side effects may occur, such as local reactions, swelling, itching, irritation, redness. Irritation affects the perianal zone.

Suppositories with palin are widely used. They are often prescribed to treat cystitis. Can be used during pregnancy and lactation. This is a natural herbal product.

Nystatin is an effective antifungal agent. Belongs to the group of polyenes. The drug is absorbed in small amounts, but it is not known how much it has the ability to combine with breast milk. It is necessary to decide how appropriate it is to continue feeding. Regarding whether the drug can be used during pregnancy, there is no data.

Macromirr has the ability to penetrate the transplacental barrier, respectively, the drug is contraindicated during pregnancy and lactation. It is allocated with breast milk.

Diclovit is produced in the form of rectal suppositories. The main active ingredient is diclofenac sodium. It is also used to eliminate bleeding, to prepare for operations, to prepare the birth canal for childbirth. It is necessary to take the remedy only after prior consultation with the doctor. It is used to treat cystitis, during pregnancy, as well as in young children.