Candles for cystitis in women: rectal, vaginal

In the structure of pathology, cystitis is almost in the first place. Therefore, suppositories for cystitis are widely used.

For cystitis in women, suppositories are prescribed. They can be used both rectally and intravaginally. It is preferable to use vaginal suppositories, since they are most effective in combating the infection that causes cystitis. Let's consider the main suppositories prescribed for cystitis in women.

• Product No. 1. Terzhinan - vaginal tablets that have an antiseptic, antifungal effect. Active ingredients: ternidazole, neomycin, nystatin, prednisolone. In addition to the effect on fungal and bacterial microflora, the active ingredients are active against trichomonads, gardnerella, and representatives of anaerobic microflora. When analyzing the pharmacological group, it is noted that the drug belongs to the aminoglycoside group.

The advantage of the drug is that it has a pronounced effect even at a high level of contamination. Resistance to it develops quite slowly.

Terzhinan is administered intravaginally, one tablet once a day. The average duration of treatment is 10 days. If the drug is prescribed for prophylactic purposes, the duration of treatment is 5-7 days. Side effects are rare. Sometimes there are reactions such as itching, burning, irritation, increased inflammation, allergic reaction. There are few contraindications. The drug is contraindicated only in case of individual intolerance to the components included in its composition. The drug can be used in the second trimester of pregnancy. During menstruation, treatment continues.

• Remedy #2. Polygynax – vaginal capsules. Prescribed for cystitis, other bacterial, fungal, inflammatory diseases of the reproductive organs and genitourinary system. Active ingredients: neomycin, nystatin, polymyxin. It has a bactericidal effect on gram-positive and gram-negative microflora, has fungicidal properties, stops the growth of yeast-like fungi. The drug is prescribed locally, 1-2 doses per day. Intensive absorption from the surface of the mucous membrane does not occur. Therefore, the drug can be used during pregnancy, before childbirth, operations, for the sanitation of the reproductive organs, genitourinary tract. As for contraindications, they include cases of individual intolerance to the drug, hypersensitivity, allergic reactions, irritation, contact eczema.
• Remedy No. 3. Voltaren in the form of suppositories is prescribed for cystitis, inflammatory diseases of the genitourinary tract, and reproductive system. The main active ingredient is diclofenac. In most cases, it is recommended to use the drug intravaginally, since in the form of rectal suppositories the drug can cause numerous side effects, in particular, it can cause irritation, burning, swelling, erosions, and inflammatory processes. It is also worth noting the pronounced analgesic effect and pain relief. Traditionally, 1-2 suppositories are administered per day. The duration of treatment is 5-7 days.
• Remedy #4. Ichthyol suppositories are an effective anti-inflammatory agent. They are used to treat cystitis, gynecological diseases, and reproductive pathologies. This remedy can be used even during pregnancy and breastfeeding. It has virtually no contraindications. It quickly eliminates inflammatory processes and stops the infectious process.

Women are better off using suppositories intravaginally, however, rectal administration of the drug is also possible. A maximum of three suppositories per day is allowed. The average course of treatment is 10 days.

• Remedy #5. Chlorhexidine is used to treat infectious diseases of bacterial and fungal infections, to relieve inflammation and infection, in acute and chronic cystitis. Chlorhexidine is effective against herpesvirus infection, chlamydial infection, trichomoniasis, ureaplasmosis, pale treponema, and a number of sexually transmitted infections. It is used in surgical pathologies, for sanitation of the reproductive tract before childbirth and surgical procedures, abortions.

Directions for use: insert the suppository deep into the vagina. The product should be inserted twice a day, the course of treatment is approximately 15-20 days. It is not recommended to combine the product with other suppositories.

• Remedy #6. Pimafucin suppositories are used to treat cystitis of various origins, to treat and prevent bacterial and viral infections. The composition includes natamycin (a substance with antifungal and antibacterial action). The drug belongs to the group of macrolides. It is worth noting the broad antifungal action.

The drug is indicated for intravaginal treatment. A single dose is 100 mg, i.e. one suppository. Frequency of administration is 1-2 times a day. Duration is 3-7 days. The drug is not used during menstruation, or is prescribed rectally.

• Remedy #7. Belladonna suppositories are used mainly as rectal suppositories, less often intravaginally. The main active ingredient is belladonna extract (a herbal remedy). The drug has a relaxing effect on the muscles of the urogenital tract and has virtually no effect on the mucous membranes, the circulatory system, or microcirculation. The method of using the drug is determined strictly individually.
• Remedy #8. Clotrimazole is a medicine used in the form of suppositories to treat thrush, cystitis, and other inflammatory and infectious pathologies. Suppositories are indicated for the treatment and prevention of venereal pathologies, fungal infections. The remedy is effective in the treatment of acute and chronic cystitis.

Clotrimazole is available in the form of vaginal tablets. The main active ingredient is clotrimazole (an antifungal agent). The tablets should be used several times a day. To achieve a lasting effect, it is necessary to undergo a course of treatment, at least 5-7 days. The suppository is inserted intravaginally, while it is necessary to insert the suppository in a supine position, with legs apart, as deeply as possible.

The drug is contraindicated in case of individual intolerance to drugs, in case of hypersensitivity. Also, the drug cannot be used during menstruation, during pregnancy. There are side effects: swelling, burning, itching at the injection site. drug. As a rule, after adjusting the course, the side effects disappear.

• Remedy #9. Polyoxidonium suppositories can be used as vaginal or rectal suppositories. The main active ingredient is azoximer bromide. It is prescribed for local and generalized infections, allergies, and immunodeficiencies. The mechanism of action consists of simulating the synthesis of interferons and hormones. Prevents the development of inflammatory and infectious pathologies. It can be used both in the remission stage and in the exacerbation stage. It can be used to treat and prevent many diseases of the genitourinary system. It is recommended to use the drug once or twice a day.
• Remedy #10. Palin suppositories are widely used to treat cystitis. The main indication for use is signs of cystitis, abdominal pain, burning during urination, pain in the kidneys and lower back. Palin eliminates inflammation, normalizes microflora, and destroys pathogenic microflora.

The main active ingredient is pipemidic acid. This is a drug with antibacterial action. The drug is prescribed 1-2 suppositories per day. The course of treatment ranges from 5-10 days.

Vaginal suppositories for cystitis

Vaginal suppositories for cystitis are prescribed to women suffering from acute or chronic cystitis.

Intravaginally prescribed: nystatin, suppositories with belladonna, terzhinan, pallene, clotrimazole, pimafucin, and other suppositories.

• Remedy #1. Nystatin is an effective antifungal agent. Belongs to the group of polyenes. The drug is active against Candida fungi. The duration of treatment is up to 14 days, 2-3 times a day.

Possible side effects: nausea, vomiting, diarrhea, skin rash, increased irritability. The drug is contraindicated in liver and kidney failure, stomach ulcers, ulcerative gastritis, drug intolerance. In the development of local irritation and allergies, during menstruation, the drug is contraindicated.

• Remedy #2. Macmiror - suppositories that have antimicrobial activity. The drug is active against gram-positive, gram-negative microflora, as well as against antifungal microflora. Taking the drug is contraindicated during pregnancy and lactation. The main indications for use of the drug are infectious and inflammatory diseases of the genitourinary tract, parasitic infections, chronic and acute pathologies. Side effects include nausea, vomiting, headache, diarrhea. During treatment, you should abstain from sexual intercourse.
• Remedy No. 3. Polygynax is available in the form of vaginal capsules. It is prescribed for cystitis, other bacterial, fungal, inflammatory diseases. The drug has mainly a pronounced local effect, which allows you to quickly achieve high therapeutic effects. The drug is prescribed locally, 1-2 doses per day. It combines well with other drugs, including suppositories, tablets.
• Remedy No. 4. Pimafucin suppositories are used to treat cystitis of various origins, for their treatment and prevention.

A single dose is 100 mg, i.e. one suppository. The frequency of administration is 1-2 times a day. The duration of treatment is approximately 3-7 days.

• Remedy #5. Clotrimazole is a medicine used in the form of suppositories to treat cystitis in women. The use of clotrimazole in the form of vaginal suppositories is the safest method of treatment. The drug is contraindicated in case of individual intolerance. The drug is intended for vaginal administration, therefore, it is prescribed only to women.
• Remedy #6. Vaginal suppositories prescribed for women with cystitis - belladonna suppositories. The main active ingredient is belladonna extract. In addition to relieving inflammation and eliminating the infectious process, it is worth noting that the drug has a relaxing effect on muscles, thereby reducing pain.

Rectal suppositories for cystitis

Sometimes there is a need to use rectal suppositories. In case of cystitis, they are most often prescribed to men. However, in case of severe inflammation, they are often prescribed to women as well. There are suppositories that are used only rectally. Let's consider some of them.

Voltaren suppositories are prescribed for cystitis, inflammatory diseases of the genitourinary tract, cystitis. It is used both as rectal and vaginal suppositories. Men are prescribed rectally, women - intravaginally for moderate inflammation, and rectally for severe inflammation. There are cases when suppositories are prescribed twice a day - rectally in the morning, intravaginally in the evening. This treatment regimen is used for long-term inflammation, progressive infection, and lack of effect from treatment. Diclofenac acts as the main active ingredient. The drug has a pronounced anti-inflammatory, anti-infective effect, is able to relieve pain, and reduce local and general temperature. It should be taken into account that in the form of rectal suppositories, the drug can cause numerous side effects: irritation, burning, swelling, erosion, increased and progression of inflammatory processes. Minor bleeding, erosion, ulcers are possible, which requires immediate discontinuation of the drug.

The dosage and duration of treatment is determined by the doctor. But usually the drug is administered 1-2 suppositories per day. The duration of treatment is 5-7 days. If the recommended dosage is followed, no side effects are observed. However, if signs of overdose or discomfort appear, you should immediately inform the doctor, as the treatment regimen may need to be revised. The initial dose is 100-150 mg/day. Gradually, the dose can be increased. It is not recommended to use the drug for patients under 18 years of age. Also, the drug is contraindicated in acute proctitis and rectitis. In case of overdose, supportive and symptomatic treatment is used. The drug is not compatible with many drugs, and this should be taken into account.

Ichthyol suppositories are also often used to treat urological and gynecological diseases. It has virtually no contraindications, is a relatively safe remedy, and can be used even during pregnancy. The main indications for use are prostatitis, cystitis, salpingitis, colitis, and vaginosis.

Suppositories are used mainly rectally. Before use, you need to empty your bowels thoroughly. It is necessary to use suppositories twice a day - in the morning and in the evening. It is best to use suppositories while lying down. The course of treatment is on average 10 days. The drug is contraindicated in case of severe allergic reactions, with increased sensitivity. It is also not recommended to use this remedy for bleeding wounds and cracks.

Chlorhexidine is prescribed for cystitis: it is effective in relieving inflammation and infection, in acute and chronic cystitis. The method of application is quite simple: it is inserted deep into the vagina or rectally. It is better for women to use it intravaginally, for men it is prescribed rectally. In order to facilitate the introduction of the drug, it is necessary to lie on your back, slightly spread your legs. The drug is not recommended to be combined with other suppositories.

Belladonna suppositories are widely used to treat cystitis. They are used in the form of rectal suppositories. This is a herbal remedy. The drug has a relaxing effect on the muscles of the urogenital tract. The drug has a number of side effects, for example, it can cause headache, nausea, vomiting, diarrhea, dry mucous membranes. The drug is contraindicated in gastrointestinal pathologies, proctitis, rectitis, prostate pathologies.

Polyoxidonium suppositories can be used in the form of vaginal or rectal suppositories. The drug has a complex effect on the body. It can be used in children under 6 years of age. The drug is used for chronic and inflammatory diseases. It is used for fungal, viral, bacterial infections, and microflora disorders. The drug is prescribed one suppository rectally or intravaginally. It is administered once a day. The duration of treatment is 5-7 days.

Palin suppositories are widely used. They are often prescribed for the treatment of cystitis. The main indication for use is signs of cystitis, abdominal pain, burning during urination, pain in the kidneys and lower back. The drug is prescribed 1-2 suppositories per day, depending on the severity of the pathological process, the severity of the pathology. The course of treatment ranges from 5-10 days. It can be used rectally or vaginally.

Diclovit is available in the form of rectal suppositories. The mechanism of action is that it has an anti-inflammatory, analgesic and antipyretic effect. It is used for inflammation, to stop the infectious process, to eliminate itching, irritation, and swelling. When administered rectally, the maximum concentration of the drug in the blood is achieved after 30 minutes. Adults are prescribed 1 suppository twice a day. The duration of treatment is on average 5-7 days, depending on the severity of the pathological process. If the drug is ineffective, the dosage can be doubled - prescribe 100 mg of the drug per day (2 suppositories). The drug is contraindicated in erosive and ulcerative lesions in the gastrointestinal tract, in case of exacerbation of chronic diseases.

Synthomycin suppositories

Syntomycin suppositories can be used for cystitis. These are suppositories that have an antibacterial effect. They are used mainly for diseases of the female reproductive system. The product is convenient, easy to use, and effective. The cost of the drug is relatively low. The main active ingredient is chloramphenicol, which has an antibacterial effect on the mucous membranes. The mechanism of action consists in inhibiting bacterial growth. The drug also prevents further reproduction of pathogenic microflora and normalizes normal microbiocenoses. The drug is active against a wide range of microorganisms: against staphylococcus, streptococcus, and neisseria. It is used in gynecology (to prepare for surgical interventions, to sanitize the birth canal before childbirth. It is also worth noting that the drug has an antifungal effect.

Prescribed only after consultation with a doctor. Self-medication is strictly contraindicated. In many ways, the dosage and method of treatment depend on the severity of the pathological process, on the etiology of the inflammation. Can be used for preventive purposes.

The distinctive feature is that the drug can be prescribed exclusively to women, since it is intended for intravaginal administration. Rectal use is not recommended, since numerous side effects are possible. Accordingly, the drug is not prescribed to men.

The method of application is described in detail in the instructions. Before use, be sure to read the instructions. First, you need to wash yourself thoroughly, using intimate hygiene products. Then dry the skin by patting it with a soft towel. Then unpack the suppository, removing the protective shell. Insert deep into the vagina: with your fingers, from a supine position. Legs should be spread apart, which will allow the drug to be inserted deeper. After the drug is inserted, you need to lie down for a while (about 30-40 minutes). It is allowed to insert 3-4 suppositories per day. The duration of treatment is 5-7 days. Side effects are mainly local: swelling, irritation, hyperemia, itching, burning. Inflammation of the mucous membranes is also possible. In case of overdose, side effects from the digestive tract are possible: nausea, vomiting, indigestion, flatulence, diarrhea. With prolonged use and overdose, changes in the hematopoietic system are possible. In particular, the number of leukocytes, lymphocytes, and platelets decreases sharply, and the leukocyte formula changes.

Syntomycin suppositories may have side effects, such as allergic reactions, itching, swelling, hyperemia. There are certain contraindications, for example, it is not recommended to use the drug for psoriasis, dermatitis, candidiasis. The drug is contraindicated during pregnancy, breastfeeding, inflammatory and infectious diseases. Not prescribed to children, adolescents. Prescribed without a prescription.

Acylact

The drug acylact is a vaginal suppository, which is widely used to treat cystitis and other inflammatory and infectious diseases of the urinary system. The drug is prescribed to women. It is inserted into the vagina, as deeply as possible. Suppositories normalize natural microbiocenoses, since the composition includes mainly acidophilic lactobacilli, which are normal representatives of the female genitourinary tract and prevent the development of the inflammatory process. The mechanism of action is that the live bacteria included in the drug have an antagonistic effect on other representatives of the microflora. Due to this, the activity of other microorganisms is inhibited. Free niches are filled with pathogenic microflora, including fungal, which leads to the development of an inflammatory and infectious process.

Acilact helps eliminate pathogenic microflora and fill free niches with lactobacilli. In turn, lactobacilli not only prevent the reproduction of pathogenic microflora, but also contribute to the formation of a natural environment. Thus, bacteria synthesize appropriate metabolites that help maintain normal pH, improve tissue trophism, and normalize metabolic processes. This helps restore natural immunity and normalizes the specific resistance of vaginal microflora. A characteristic feature is that lactobacilli promote glycogen metabolization, due to which lactic acid is formed, which maintains optimal parameters of the vaginal environment.

Atsilakt is often prescribed for the prevention of cystitis, or after a course of antibiotic therapy, since it helps to normalize the microflora and maintain the normal condition of the mucous membranes. It can be used when the first signs of the disease appear. Eliminates dysbacteriosis. It is used to treat and prevent the genitourinary system, venereal diseases. Due to the fact that the drug increases local immunity, maintains the colonization resistance of the mucous membranes, it also has an effect against viral infections. It is used for acute, chronic and recurrent diseases.

One dose of the drug contains approximately 10 million live bacteria. One tablet is one dose. It is prescribed 1-2 doses per day. Acylact can be used intravaginally not only in the form of suppositories, but also in the form of a spray intended for irrigation of mucous membranes. Sometimes applications are used. In case of recurrent diseases, progression of the inflammatory and infectious process, the dosage can be increased to 5 doses per day. The duration of treatment is on average 5-15 days. According to indications, treatment can be continued until the complete disappearance of clinical symptoms of the pathology. For control, the purity of vaginal secretions is checked (scraping, smears, bacteriological cultures). Side effects are rare. Sometimes allergic reactions are observed. The drug is contraindicated in case of hypersensitivity to the components of the drug, in case of individual intolerance. The drug should not be used for candidiasis and other forms of fungal infection. It is not recommended to prescribe to children, during pregnancy and breastfeeding, in case of immunodeficiency. It is important that suppositories can be combined with other medications, as well as with other suppositories. Can be used simultaneously with antibacterial, antiviral and antifungal agents. Enhances the effect of local immunomodulatory agents.

Pharmacodynamics

Speaking about pharmacodynamics, it is worth noting that almost all suppositories used for cystitis have an antiseptic, antifungal effect. The composition includes mainly antiseptic, less often - anti-inflammatory agents. Many drugs have an analgesic, anti-inflammatory effect. Suppositories are classified as combined products intended for local use. A characteristic feature of many suppositories is that it ensures the integrity of the mucous membrane, and also maintains constant acidity in the vaginal environment. Some suppositories are aimed at influencing the fungal microflora (the effect is directed mainly against yeast-like fungi belonging to the genus Candida). Often suppositories have a bactericidal effect on gram-positive and gram-negative microflora. A characteristic feature is that in addition to the main antiseptic effect, suppositories have the ability to improve trophic processes, normalize metabolism, improve blood circulation and blood microcirculation. Suppositories have mainly a pronounced local effect, which allows for rapid achievement of high therapeutic effects. Suppositories are not absorbed into the systemic bloodstream. This allows for avoiding many side effects and contraindications.

The mechanism of action of suppositories is that intensive absorption from the surface of the mucous membrane does not occur. Therefore, many suppositories can be used during pregnancy, before childbirth, operations, for the sanitation of the reproductive organs, genital tract. Many rectal suppositories, in addition to the traditional anti-inflammatory and antiseptic effect, have a protective effect in prostatitis, strictures and injuries of the urethra and ureters. Therefore, rectal suppositories are recommended for use in acute and chronic interstitial cystitis, in its relapses.

It is also worth noting the ability of many suppositories to relieve pain, to reduce temperature. The mechanism of action of such suppositories is that they significantly inhibit the synthesis of prostaglandins, which are directly involved in the development of inflammation, pain, fever. Many suppositories allow you to quickly restore scars, eliminate swelling and inflammation, and stop the infectious process.

Pharmacokinetics

When analyzing the pharmacokinetics, it was found that the components included in the suppositories are absorbed quite quickly through the mucous membranes, slightly absorbed into the blood. That is, most suppositories have a local (local) effect, which allows them to be used to treat inflammatory processes in the genitourinary tract. The higher the dose, the more the drug is absorbed. Most suppositories bind approximately 90-99% of the substance to blood plasma proteins. It is also worth noting that suppositories have the ability to penetrate into liquids (blood, lymph, and other biological fluids) after about 3-4 hours. The concentration remains high for up to 12 hours, so the use of many suppositories twice a day is justified. When the recommended dosage is observed, no side effects are observed, and there is no accumulation of the substance in tissues. Most of the drug is metabolized through the liver. It should also be taken into account that some suppositories are found in small quantities in breast milk, which does not allow them to be used during pregnancy and lactation. There are suppositories that do not penetrate into milk. Suppositories are indicated for inflammatory processes in the genitourinary system, gynecological and degenerative diseases, acute and chronic pathologies, and various forms of cystitis. It is recommended to use for severe pain syndrome, when preparing for operations, for traumatic syndrome, when preparing for operations and childbirth.

Use cystitis suppositories during pregnancy

Not all suppositories can be used for cystitis during pregnancy. Some of them have the ability to penetrate the transplacental barrier, and accordingly, can affect the fetus. This excludes the possibility of using such suppositories during pregnancy. If the active substances do not penetrate the transplacental barrier, but have only a local effect, they can be prescribed during pregnancy. In any case, suppositories can be used only after consulting a doctor. Let's consider the main suppositories used to treat cystitis.

Thus, terzhinan is often used. However, in the 3rd trimester the drug is contraindicated, as it can cause insufficient opening of the cervix.

Ichthyol suppositories cause a minimum of side effects and have virtually no contraindications. This remedy can be used even during pregnancy and breastfeeding.

Chlorhexidine can be prescribed during pregnancy. It acts within the mucous membrane and is not absorbed into the blood. This allows the drug to be used during pregnancy and breastfeeding. It is used in surgical pathologies, for sanitation of the reproductive tract before childbirth and surgical procedures, abortions, in preparation for the introduction of an intrauterine device and other similar devices.

Pimafucin is one of the few drugs approved for use during pregnancy. Pimafucin suppositories are used to treat cystitis of various origins, to treat and prevent bacterial and viral infections of the genital and reproductive tract.

Belladonna suppositories are widely used to treat cystitis during pregnancy. The drug has virtually no effect on the mucous membranes, circulatory system, or microcirculation. In addition to acute and chronic cystitis, the drug is recommended for vaginosis, bacterial and viral infections, and for the treatment and prevention of reproductive tract diseases. This drug is indicated in preparation for surgeries, abortions, and for sanitizing the birth canal before childbirth. The regimen and method of using this drug is determined in each specific case strictly individually. Therefore, before use, you should consult a doctor. When applied locally, burning, irritation, and minor erosions are possible.

Clotrimazole is an effective remedy against bacterial and fungal infections. The use of clotrimazole in the form of suppositories is the safest method of treatment. This is due to the fact that clotrimazole in the form of suppositories practically does not penetrate into the systemic bloodstream, due to which side effects are possible, or do not occur at all. It acts directly at the site of inflammation. This allows the use of clotrimazole during pregnancy. Clotrimazole is often prescribed to women for the treatment of vaginal pathologies, to normalize microflora, and to stop the inflammatory and infectious process. Clotrimazole is prescribed for preventive purposes, for the treatment and relief of the inflammatory process, for the sanitation of the birth canal before childbirth, to prepare for operations, and the placement of an intrauterine device. However, the instructions indicate that it is not recommended to use in the first trimester of pregnancy. In the third trimester, the drug is contraindicated. The drug should not be used in the second trimester, however, in case of extreme necessity, the drug can be prescribed in the second trimester. It is worth noting that the drug is administered intravaginally using a special applicator. However, during pregnancy, the drug should be administered by hand, without using an applicator.

Polyoxidonium suppositories can be used as vaginal or rectal suppositories. It has an immunomodulatory, detoxifying, antioxidant, anti-inflammatory effect. It can be used during pregnancy and lactation. Side effects may occur, such as local reactions, swelling, itching, irritation, redness. Irritation affects the perianal area.

Palin suppositories are widely used. They are often prescribed for the treatment of cystitis. Can be used during pregnancy and breastfeeding. This is a natural herbal remedy.

Nystatin is an effective antifungal agent. It belongs to the group of polyenes. The drug is absorbed in small quantities, but it is unknown to what extent it has the ability to combine with breast milk. It is necessary to decide how appropriate it is to continue breastfeeding. There is no data on whether the drug can be used during pregnancy.

Macromirr has the ability to penetrate the transplacental barrier, therefore, the drug is contraindicated during pregnancy and breastfeeding. It is excreted in breast milk.

Diclovit is produced in the form of rectal suppositories. The main active ingredient is sodium diclofenac. It is also used to stop bleeding, to prepare for operations, to prepare the birth canal for childbirth. The drug should be taken only after prior consultation with a doctor. It is used to treat cystitis, during pregnancy, and in young children.