Pills from skin fungus

Fungal lesions of the skin are not less common than viral or infectious diseases. At the moment, there are more than 400 varieties of fungi that can trigger the development of diseases of skin and mucous tissues, as well as internal organs. Nevertheless, modern medicine successfully fights against fungal infection, using antifungal agents for external and oral administration. Creams and ointments act at the local level when applied to surface tissues. Tablets from the fungus of the skin have a systemic effect, destroying the infection not only from the outside, but also inside the body.

[1], [2], [3], [4], [5], [6], [7], [8], [9]

Indications of the tablets against skin fungus

Tablets from the skin fungus are designed to treat various types of fungal diseases caused by opportunistic and pathogenic fungi.

• Keratomycosis is a disease of the superficial epidermal layer, horny layer and cuticle, without inflammatory process. Keratomycosis, in turn, is divided into the following types of pathologies:
  • colored lichen;
  • knotty trichosporia.
• Dermatophytosis is a fungal lesion of deep cutaneous layers, right down to the appendages of the skin. The category of dermatophytes include:
  • epidermophyty;
  • trichophytosis;
  • rubrophytic;
  • favus;
  • microsporium.
• Candidiasis are the most common fungal diseases affecting the skin, appendages and even internal organs.
• Mycosis is the defeat of the fungi of the skin and underlying tissues. The most known mycoses are:
  • blastomycosis;
  • Maduromycosis;
  • sporotrichosis;
  • chromomycosis;
  • coccidiomycosis;
  • rhinosporidiosis;
  • histoplasmosis.
• Trichomycosis is a fungal infection that causes fungi of Microsporium and Trichophyton.
• Actinomycosis is a disease provoked by conditionally pathogenic radiant fungi.

[10], [11], [12], [13], [14], [15], [16], [17], [18]

Dosing and administration

In most cases, at the initial stage of antifungal treatment, the doctor prescribes external medicines: ointments, creams, gels. If the local treatment does not have the expected effect, then in this case, include tablet drugs and conduct complex therapy.

Next, we offer you a schematic list of the most effective and common tablets from the skin fungus.

Tablets from the fungus of the appendages of the skin

Itraconazole
Pharmacodynamics Pharmacokinetics	Synthetic tablets from skin fungus with a wide spectrum of activity. The drug is maximally available when taken immediately after a meal. The maximum concentration in the blood is detected for 3-4 hours.
Use of tablets against skin fungus during pregnancy	Can be prescribed only with systemic fungal infection, when the risk of fetal damage exceeds the degree of toxic effect of the drug.
Contraindications for use	Allergy.
Side effects	Stool disorders, nausea, hepatitis, headaches, allergies, menstrual irregularities in women.
Method and dosage of tablets against skin fungus	The treatment schedule is determined individually. The average reception of the drug is from 0.1 to 0.2 g once a day. Treatment lasts for up to several months.
Overdose	There is no information.
Interactions with other drugs	Do not use in combination with terfenadine, midazolam, cyclosporine, vincristine, digoxin.
Storage conditions and shelf life	Save up to 2 years at room conditions.

Terbinafine
Pharmacodynamics Pharmacokinetics	Tablets from the fungus, a representative of allylamines. Well absorbed from the digestive tract, bioavailability is about 50% (regardless of food intake).
Use of tablets against skin fungus during pregnancy	Clinical data on the use of tablets in pregnancy are not enough to call the drug absolutely safe. Therefore, it is not recommended to take tablets from the fungus during this period.
Contraindications for use	Allergy.
Side effects	Allergic manifestations, anxiety, depression, eating disorders, numbness of the limbs, pain in the head, changes in appetite, hearing and vision impairment, fatigue.
Method and dosage of tablets against skin fungus	Tablets take 1 pc. (250 mg) once a day. The average duration of therapy is up to 4-6 weeks.
Overdose	Pain in the head, attacks of nausea, dizziness.
Interactions with other drugs	Combination with fluconazole, rifampicin, cyclosporins, caffeine is not desirable.
Storage conditions and shelf life	Save up to 4 years in an indoor setting, out of the reach of children.

[19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29]

Tablets from foot skin fungus

Ketoconazole
Pharmacodynamics Pharmacokinetics	Tablets from the fungus, related to the derivatives of imidazole. Limit concentration is detected after an hour and a half after taking the drug.
Use of tablets against skin fungus during pregnancy	Tablets are contraindicated in pregnancy.
Contraindications for use	The likelihood of allergies, severe kidney and liver diseases, the period of pregnancy and breastfeeding. It is not used in pediatrics.
Side effects	Abdominal pain, dyspeptic disorders, headaches, frustration, sleep disturbances, allergies, febrile conditions, gynecomastia, decreased sexual desire.
Method and dosage of tablets against skin fungus	Tablets are prescribed in an amount of 200 mg per day at a time, with meals. The duration of antifungal therapy depends on the specific disease.
Overdose	There is no description of an overdose, but a certain increase in side effects is permitted.
Interactions with other drugs	It is undesirable to take tablets together with anti-acid, anticholinolytic drugs, beta-blockers, isoniazid, rifampicin.
Storage conditions and shelf life	The drug can be stored for up to 2 years, under normal conditions.

Lamisil
Pharmacodynamics Pharmacokinetics	Antifungal tablets based on terbinafine. Fungicidal activity begins to manifest itself within an hour and a half after the internal administration of the drug.
Use of tablets against skin fungus during pregnancy	Full-fledged studies regarding the negative effect of the drug on pregnancy and fetus have not been conducted. For this reason, taking tablets from the skin fungus to pregnant women is not recommended.
Contraindications for use	Probability of an allergic reaction.
Side effects	Anemia, allergic manifestations, worsening of appetite, anxiety, taste disorders, headaches, vertigo, taste disorders, vasculitis, pancreatitis.
Method and dosage of tablets against skin fungus	Tablets take 1 pc. (250 mg) once daily.
Overdose	Overdose can be accompanied by headache, nausea, pain in the stomach.
Interactions with other drugs	It is not recommended to combine with cimetidine, fluconazole, rifampicin.
Storage conditions and shelf life	Keep up to 3 years, at room temperature, away from children's access.

Tablets from hand skin fungus

Fluconazole
Pharmacodynamics Pharmacokinetics	Tablets from the fungus belong to the derivatives of triazole. The active substance penetrates into all tissues and fluids in the body. Bioavailability is equivalent to 90%.
Use of tablets against skin fungus during pregnancy	In pregnancy, fluconazole treatment should be avoided.
Contraindications for use	Allergy to fluconazole preparations, the period of pregnancy and breastfeeding.
Side effects	Dyspeptic disorders, liver intoxication, skin rashes, allergic manifestations, jaundice, tachycardia.
Method and dosage of tablets against skin fungus	The average dosage of tablets is 100-200 mg per day.
Overdose	Cases have not been described.
Interactions with other drugs	Avoid interactions with terfenadine and cisapride.
Storage conditions and shelf life	Tablets are stored for up to 2 years in a dry room.

Griseofulvin
Pharmacodynamics Pharmacokinetics	Tablets-fungistatiki, possessing a cumulative effect, which practically excludes the development of resistance of fungi.
Use of tablets against skin fungus during pregnancy	Tablets are not used in pregnancy because of the risk of developing birth defects in the fetus.
Contraindications for use	The likelihood of allergies, a significant degree of leukopenia, blood diseases of a systemic nature, severe kidney and liver pathologies, autoimmune diseases, malignant tumors, lactase insufficiency.
Side effects	Dyspeptic disorders, allergies, migraine-like headaches, fatigue, anxiety, depression, impaired renal function, menstrual irregularity in women, arrhythmia, aversion to alcohol, eye pain, stomatitis, fever, swelling, muscle pain.
Method and dosage of tablets against skin fungus	Tablets take 0.5 g twice daily, immediately after ingestion, with a small amount of vegetable oil (1 tsp).
Overdose	It did not happen.
Interactions with other drugs	You should not combine the drug with barbiturates, sedatives, alcohol, contraceptives for internal reception.
Storage conditions and shelf life	Tablets are kept in a place difficult to reach for children, up to 4 years.

Tablets from skin fungus in children

Diflucan
Pharmacodynamics Pharmacokinetics	Tablets, triazole derivatives. Have good digestibility and bioavailability.
Use of tablets against skin fungus during pregnancy	A short course of treatment is allowed only in case of emergency.
Contraindications for use	Probability of allergy.
Side effects	Pain in the head, abdominal pain, indigestion, allergic rashes, sleep disturbances.
Method and dosage of tablets against skin fungus	Tablets can be prescribed to children from 5 years of age, in an amount of 3-6 mg per kilogram of body weight per day.
Overdose	Disorders of consciousness, disorientation, hallucinations.
Interactions with other drugs	Do not appoint together with erythromycin, quinidine, cisapride, astemizole, pimozide, terfenadine.
Storage conditions and shelf life	The preparation does not require special storage conditions. Can be stored in factory packaging for up to 5 years.

Fungal diseases, in general, require a long course of antifungal therapy. Therefore, the outcome of the disease largely depends on the patient himself, or rather, on his patience and self-discipline. In order to qualitatively get rid of the fungus of the skin, you must strictly follow all the doctor's recommendations and carefully follow the prescribed treatment regimen. In addition, compliance with the rules of hygiene and sanitation is also important, because otherwise the infection can not be repeated. If the taking of tablets is stopped before the doctor's appointed time, it is possible to form more resistant fungal variations, which will become much more difficult to destroy. Remember: for a successful cure it is very important to take the pills from the fungus of the skin exactly as prescribed by the doctor in charge.