Hayle Flox

Haylefloks is a medicinal preparation used for the treatment of infectious and inflammatory diseases of various severity. Let's consider the indications for the use of the drug, possible side effects and a number of contraindications.

Hailefleks is a remedy that fights microorganisms that infect infectious and inflammatory diseases. The drug is prescribed for medical reasons. The peculiarity of this drug is an active substance, which begins to work immediately after taking the drug. Let's look at the basic indications for the use of the Haileflox.

Indications Hayle Flox

Indications for use Hylefloks are based on the active substance of the drug. Let's consider in what cases the drug is prescribed for use.

• Infectious diseases of the lower respiratory tract ( chronic bronchitis, pneumonia );
• Bacterial sinusitis (acute);
• Intra-abdominal infection (except for Hailefloq prescribe a course of antibacterial antibiotics that act on the anaerobic microflora of the body);
• Infectious diseases of the kidneys and urinary tract;
• Bacterial prostatitis;
• Acute pyelonephritis;
• Infectious lesions and diseases of soft tissues and skin (abscesses, atheromas, furuncles, abscesses);
• Complex therapy of a stable form of tuberculosis;

Release form

The form of release Haylefloks - tablets. The drug is released in packs of 250 mg, 500 mg and 750 mg of the active ingredient. Tablets produce in a blister for 3, 5 or 10 tablets. In one package there is one blister of the drug. Note that tablets are also available in large doses, especially for hospital inpatient departments. So, Haylefloks produce in bags of PVC for 100, 500 and even 1000 tablets. Each packet with tablets is placed in a can of PE with high density.

This form of Haileflox is convenient for use. The drug is available with a different dosage and number of tablets. This allows you to calculate in advance how much is needed to complete the course of treatment.

Pharmacodynamics

Pharmacodynamics Haylefloks are the processes and actions that take place with the active substance of the drug after ingestion. The active substance of the drug is levofloxacin. Levofloxacin is a synthetic fluoroquinolone with a broad spectrum of action. The substance inhibits DNA gyrase and topoisomerase, suppresses the synthesis of DNA, disrupts the fusion of DNA disruption and causes profound morphological changes in cells, cytoplasm and sensitive microorganisms.

The active ingredient Haleflex is active against:

• Aerobic Gram-positive microorganisms;
• Aerobic Gram-negative microorganisms;
• Anaerobic microorganisms.

Pharmacokinetics

Pharmacokinetics Hailefleks are the processes of absorption, distribution, metabolism and excretion of the drug. Let's take a closer look at how these processes occur in the human body.

• Suction - after taking, the active substance of the drug levofloxacin is completely absorbed by the gastrointestinal tract. The drug is absorbed very quickly, within a couple of minutes after ingestion. Prima food does not affect the absorption of the drug. Bioavailability of Haileflox is 99%, and the concentration of active substance in the blood plasma reaches 2-3 times the maximum level for the preparation of this species.
• Distribution - binding of the drug to plasma proteins is 30-40%. The active substance perfectly penetrates into tissues and organs. Active components penetrate into the mucous membrane of the lungs and bronchi, alveolar macrophages, organs of the genitourinary system.
• Metabolism - the drug is metabolized in the liver, causes deacetylation or oxidation.
• Excretion - Hailefleks is excreted from the body in an unchanged form with the help of kidneys. So, 70% of the accepted dose of the drug is excreted within 24 hours, the remaining part within 72 hours is excreted with feces.

Dosing and administration

The method of administration and dose of the drug is prescribed individually for each patient and depends on many factors - the age of the patient, the symptomatology of the disease, the presence of chronic diseases and contraindications to the use of Hayleflox. The intake of the drug does not depend on meals. Let's look at the methods of application and the dose of Haileflox.

• Hospital pneumonia is a daily dose of 750 mg, the duration of treatment is 1-2 weeks.
• Exacerbation of chronic bronchitis - a daily dose of 500 mg Haileflex, the duration of treatment is 7 days.
• Complex therapy of tuberculosis - the drug is taken twice a day for 500 mg, the duration of treatment is up to three months.
• Skin diseases and subcutaneous tissue infections - take Haileflex once a day, not more than 500 mg, the duration of treatment - no longer than 10 days.
• Urinary tract infections - take 250-750 mg of the drug, from one to ten days.
• Intra-abdominal infection - take 500 mg of Haileflox, treatment from a week to two.

If the drug is prescribed to patients with renal insufficiency, the dose of Haileflox preparation is selected individually for each patient.

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Use Hayle Flox during pregnancy

Use of Haileflox during pregnancy is prohibited. Taking the drug in the first trimester of pregnancy can cause miscarriage and bleeding. But in later terms, Haileflox leads to problems and complications during childbirth. The drug can cause pathologies in the development of the baby.

It is forbidden to use Heilflox in the period of breastfeeding. Together with the mother's milk, the drug enters the child's unprotected body. Therefore, it can cause overdose symptoms and other complications. During lactation, it is necessary to refuse to breast-feed a child if taking the medication is necessary by medical indicators.

Contraindications

Contraindications to the use of Haileflox are based on the individual intolerance of the active substance of the drug and its other components. Hailefloqs has contraindications for use and for medical reasons, let's consider them.

• The lesions and diseases of the tendons, which are associated with the use of quinolones in the anamnesis;
• Adolescent to 18 years and children's age of patients;
• Pregnancy and lactation;
• Epilepsy;
• Hypersensitivity to fluoroquinolones and the active substance of the drug - levofoksatsinu.

The drug is administered with caution to elderly patients, since there is a danger of a decrease in kidney function, as well as a deficiency of glucose-6-phosphate dehydrogenase. It is not recommended to take the medication independently, the doctor should indicate the dosage and check the patient for contraindications.

Side effects Hayle Flox

Side effects of Haileflox are manifested due to incorrect dosage of the drug or the presence of contraindications to the active substance of the drug. Let's look at the most common side effects of the Haileflox.

• Dizziness and headache;
• Tremor of limbs and anxiety;
• Hypercreatininaemia, renal insufficiency;
• Neutropenia, muscle weakness, rupture of tendons;
• Allergic reactions on the code, bronchospasm, choking;
• Persistent fever, development of superinfection;
• Nausea, vomiting, diarrhea and other symptoms.

If side effects of the drug occur, you should stop taking the drug and seek medical help.

[1], [2]

Overdose

Symptoms of overdose, as side effects of the drug are manifested when applying a high dose of the drug. The main symptoms of an overdose are:

• Nausea
• Vomiting
• Confusion of consciousness
• Lesion of the gastrointestinal tract
• Dizziness
• Convulsions
• Tremor of the extremities

To treat symptoms of an overdose, stop taking the medication and seek medical help. The doctor will prescribe symptomatic therapy and gastric lavage. Note that there is no antidote for the treatment of an overdose of Haileflox, and the dialysis procedure is considered ineffective.

Interactions with other drugs

Interaction Hailefleks with other drugs is possible only with the permission of a doctor. The use of active ingredient Haileflox - levofloxacin with other drugs reduces the medicinal properties of the drug. So, in patients there is an oppression of intestinal motility.

The simultaneous use of non-steroidal anti-inflammatory drugs and Haileflox is the cause of seizures and the risk of rupture of tendons. The simultaneous use of HAILLEFLOX with hypoglycemic drugs can lead to a change in the level of glucose in the blood and lead to hypoglycemia. When applying Hailefloks with warfarin, the medicinal properties of the latter are intensified.

[5], [6], [7]

Storage conditions

The storage conditions of the Haileflox are described in the product instructions. Heyleflex should be stored in a dark, cool, dry place, which is protected from sunlight and children. Storage temperature of the preparation is from 8 ° to 25 ° C.

Please note that if the storage rules are not observed, the drug loses its medicinal properties. So, because of temperature changes or under the influence of direct sunlight, tablets can change color and even acquire a peculiar smell. In this case, take the drug is prohibited.

Shelf life

The shelf life of the Haileflox is indicated on the package of the drug and is 36 months, that is three years. At the expiration of the expiration date the drug is forbidden to use, as its use can lead to adverse effects with the body. The drug must be disposed of. Please note that storage conditions affect the shelf life of the drug.

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