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Halazolin
Last reviewed: 23.04.2024
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Galazolin refers to symptomatic preparations for topical treatment of a common cold of various etiologies in therapeutic, pediatric and otolaryngological practice. This nasal agent has many analogues, including Grippostad Reno, Otrivin, Vonos, Doctor Tayss Nazolin, Influrin, Xylen, Xyloben, Rinazal, Rhinorhom, Rhinostop, Snoop, Suprima-NOZ, Tysin, Pharmazoline and others.
Indications Halazolin
Galazolin is recommended to use to relieve the stuffiness of the nose and improve new breathing in acute rhinitis caused by viral and bacterial infections, as well as allergic rhinitis, chronic rhinitis, nasopharyngitis. Indications for the use of galazolin in otolaryngology are: inflammation of the mucous membranes of the paranasal sinuses ( sinusitis ), allergic sinusopathies, sinusitis, vasomotor rhinitis, in which this drug facilitates the passage of secretions.
In addition, to remove swelling of the mucous nasopharynx Galazoline can be used in complex therapy of inflammation of the middle ear (otitis).
Release form
Galazolin is available in two dosage forms: in the form of nasal gel (in tubes of 10 grams) and solution (in 10 ml bottles) - for application in the form of a drop.
Pharmacodynamics
The mechanism of local symptomatic effects of the drug Galazolin is based on the vasoconstrictive effect of its active substance - xylometazoline hydrochloride.
This substance refers to anticongestants (decongestants) and alpha-adrenergic stimulants. Getting on the mucous membranes of the nose or nasopharynx, xylometazoline hydrochloride stimulates postsynaptic adrenoreceptors (alpha-adrenergic receptors). In response to irritation, a typical alpha-adrenergic effect arises - narrowing of the vessels. The narrowing of the lumens of the blood vessels of the nose and paranasal sinuses, in turn, leads to a rapid decrease in the edema of the nasal passages and a reduction in the volume of mucus secretion. As a result, nasal breathing is restored.
Pharmacokinetics
After the administration of drops or gel, galazoline therapeutic effect begins to be felt at least after 3-5 minutes and can last up to 8-10 hours. However, prolonged use of this drug can lead to a rapid decrease in the therapeutic effect.
Both drops and gel are applied topically (intranasally), so they are almost not absorbed in the blood plasma.
Dosing and administration
0.05% drop. Halozolin is prescribed for children over three years old - 1-2 drops per nostril no more than twice a day. Adults and children after six years should drip 2-3 drops in each nostril 2-3 times a day. Maximum duration of application is 14 days
Galazolin in the form of a gel is used in this dosage: children 3-6 years, one injection into each nostril - 1-2 times a day; children over 6 years and adults - 1-2 injections into each nasal passage 2-3 times during the day.
Use Halazolin during pregnancy
Use of galazoline during pregnancy is not recommended. If there is an extreme need, the prescribing should be prescribed by the attending physician - with the exact observance of the maximum permissible dose.
Contraindications
Among the contraindications to the use of galazolin are such diseases as
Ozona (atrophic rhinitis), arterial hypertension, diagnosed atherosclerosis in severe form, diabetes mellitus, hyperthyroidism (hyperthyroidism) and glaucoma (closed-type).
Side effects Halazolin
The use of any form of galazoline (and its analogs) can cause such side effects as burning in the nose, reddening of the mucosa and reflex response of adrenoreceptors in the form of sneezing.
It should be borne in mind that the continued use of galazoline in chronic nasal congestion can lead to dryness of the mucosa and a disorder of its sensitivity with a temporary loss of smell. It is possible that the mucosal secretions from the nasal cavity, increased heart rate, increased blood pressure, the appearance of headaches and insomnia.
Also, with prolonged intake of galazoline, the ability to drive vehicles and mechanisms can be reduced.
[1]
Overdose
Possible overdose of Halazolin is determined by the following symptoms: headache, tachycardia, increased blood pressure, nausea, insomnia and a sense of anxiety.
Storage conditions
Storage conditions: Galazolin: protected from light and inaccessible to children, optimal temperature regime - + 15-25 ° C.
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Shelf life
Shelf life: drops - 4 years, gel - 3 years from the date of production.
Attention!
To simplify the perception of information, this instruction for use of the drug "Halazolin" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.