What can be substituted for Furadonin for cystitis?

Today, the pharmaceutical market offers many drugs that are effective in treating cystitis of any etiology. To eliminate infectious causes of the disease, antimicrobial agents are used. This pharmacological group includes Furadonin. There are also analogous drugs that are not inferior in their therapeutic effect. Let's consider some of them:

Furasol

An antimicrobial agent with the active substance furagin. It is active against gram-positive and gram-negative microorganisms, including strains resistant to other antibiotics.

• Indications for use: complex therapy of infectious and inflammatory diseases. Cystitis, urethritis, pyelonephritis, oropharyngeal infections, infected wounds, keratitis. Prevention of complications in urological operations, cystoscopy, catheterization.
• Directions for use: dissolve the contents of the sachet in a glass of hot water. Take the prepared solution orally 3-4 times a day for 3 days.
• Side effects: nausea, vomiting, headaches and dizziness, allergic reactions, changes in urine color. No cases of overdose have been recorded.
• Contraindications: hypersensitivity to active ingredients, pregnancy and lactation, patients under 4 years of age.

Release form: powder for solution preparation, in 1 g sachets, 15 pieces per package.

Urofuragin

Antibacterial agent of systemic action. Contains the active component - furagin, a derivative of nitrofuran. Has bacteriostatic and antiprotozoal properties. Used to treat urinary tract infections. The drug is taken orally 150 mg 2-3 times a day for 5-10 days.

Urofuragin is contraindicated in case of intolerance to nitrofuran derivatives or auxiliary components. It is not prescribed during pregnancy and lactation, porphyria, renal failure, for pediatric patients.

Palin

An antibacterial agent used in urology and gynecology. Contains an active substance from the quinolone group – pipemidic acid. Inhibits the bacterial DNA enzyme that regulates replication, transcription and reparation. Palin has bactericidal and bacteriostatic properties.

• Indications for use: acute and chronic diseases of the urinary tract and bladder. Recurrent urinary tract infections, vaginal infections.
• Method of administration: orally, 2 capsules 2 times a day. Duration of treatment is 10 days. If the tablets are used for preventive purposes, the treatment can last up to 6 months.
• Side effects: nausea, vomiting, loss of appetite, diarrhea, flatulence, skin allergic reactions. Emotional instability, visual and sleep disturbances, headaches and dizziness.
• Contraindications: hypersensitivity to the components of the drug, pregnancy and lactation, age under 15 years. It is prescribed with caution to patients with epilepsy, a tendency to seizures, severe renal dysfunction.
• Overdose: headache, dizziness, tremor of the extremities, nausea and vomiting, confusion. Treatment is symptomatic, hemodialysis is effective.

Release form: capsules of 10 pcs. in a blister, 2 blisters in a package

Negroes

Uroantiseptic with antimicrobial action. Contains the active component - nalidixic acid 500 mg. Depending on the concentration of pathogenic microorganisms, it exhibits bacteriostatic or bactericidal action.

• Indications for use: cystitis, urethritis, urethral syndrome, pyelonephritis and other infectious and inflammatory diseases of the genitourinary system. Prevention of infection during surgical procedures on the bladder, kidneys, ureters.
• Method of administration: orally, with plenty of water. For adults, 1 g every 6 hours during the first week of treatment. For children over 2 years old - 60 mg/kg, maintenance dose 30 mg/kg every 6 hours.
• Side effects: nausea, vomiting, increased sleepiness, headaches, increased intracranial pressure, allergic reactions. Overdose has more pronounced symptoms. Treatment includes gastric lavage with 3% sodium bicarbonate solution and further therapy.
• Contraindications: intolerance to the components of the drug, children under 2 years of age, pregnancy and lactation, epilepsy, renal and hepatic insufficiency, glucose-6-phosphate dehydrogenase deficiency, atherosclerosis of the cerebral vessels.

Release form: tablets of 500 mg, 56 pieces per package.

Norbactin

A broad-spectrum antimicrobial agent. Contains an active substance from the fluoroquinolone group – norfloxacin. Has a pronounced bactericidal effect on aerobes.

• Indications for use: infectious diseases of the urinary system, gastrointestinal tract, uncomplicated gonococcal infection. Prevention of traveler's diarrhea.
• Method of administration: orally, 1 hour before meals or 2 hours after. For cystitis, take 1 tablet 2 times a day. Duration of treatment is 3 days. If cystitis is acute, therapy can last up to 21 days.
• Side effects: nausea, vomiting, pain in the epigastric region, skin allergic reactions, headaches and dizziness, sleep disturbance. Overdose has similar symptoms. There is no specific antidote, treatment is symptomatic.
• Contraindications: intolerance to the components of the drug, glucose-6-phosphate dehydrogenase deficiency, renal failure, pregnancy and lactation, children under 16 years of age.

Release form: oral tablets with enteric coating, 10 pieces per blister, 1, 10 blisters per package.

Furagin or Furadonin

Both drugs have an antimicrobial effect. They contain an active component from the group of nitrofuran derivatives. They are used for infectious inflammatory lesions of the genitourinary system.

Furagin is an antimicrobial drug. Its mechanism of action is based on the effect on the enzymes of microbial cells that carry hydrogen molecules. This provides a pronounced bacteriostatic effect. The active component affects a wide range of gram-negative and gram-positive microorganisms. It works well with acidic pH of urine; in an alkaline environment, the drug's activity is limited.

• Indications for use: infectious and inflammatory diseases of the urinary system and prostate gland in acute/chronic form. Preventive measure for recurrent pathologies when long-term catheterization of the bladder is necessary. Congenital anomalies of the bladder.
• Method of administration: orally during meals. Adult patients are prescribed 100 mg 4 times a day on the first day of treatment, followed by a reduction in dosage to 100 mg 3 times a day. The dosage for children is calculated at 5-7 mg/kg per day. Duration of therapy is 7-8 days. After 10-14 days, treatment can be resumed. For prevention, 50 mg before bedtime.
• Side effects: increased drowsiness, blurred vision, headaches and dizziness. Dyspeptic disorders, diarrhea, constipation, nausea and vomiting. Skin allergic reactions, general malaise.
• Contraindications: intolerance to components, patient age up to 7 days of life, pregnancy and lactation, renal failure, polyneuropathy, congenital deficiency of the enzyme glucose-6-phosphate dehydrogenase.
• Overdose: headaches, dizziness, nausea, liver dysfunction, allergic reactions, peripheral polyneuritis. Gastric lavage and infusion therapy are indicated for treatment. In particularly severe cases, hemodialysis is performed.

The medicine is available in 50 mg tablets with 30 capsules per package.

Since Furagin and Furadonin have the same mechanism of action, the final decision on the choice of the most suitable drug should be made by the attending physician.

Furazolidone or Furadonin

The drugs differ in their mechanism of action and active components. Furadonin is an antimicrobial agent and is used to treat urological pathologies. Furazolidone is an auxiliary drug in the complex therapy of cystitis.

Furazolidone is an antibacterial agent of the nitrofuran group. Contains the active substance - furazolidone 50 mg. Has pronounced activity against gram-negative aerobic microorganisms. Less effective against gram-positive aerobes.

The antimicrobial action of the drug is based on the ability of the nitro group of the active component to be reduced to an amino group under the influence of bacterial enzymes. It has immunostimulating properties. Increases the phagocytic activity of leukocytes, reduces the production of toxins by microorganisms.

• Indications for use: infectious diseases of the genitourinary system, gastrointestinal tract, skin. Prescribed in the complex therapy of cystitis, trichomonas infections, vaginitis, urethritis, pyelitis. Effective in bacillary dysentery, typhoid, paratyphoid, infectious diarrhea. Suitable for the treatment of patients with infected wounds and burns.
• Method of administration: orally, after meals. The dosage depends on the severity of the disease and the age of the patient, so it is determined by the attending physician.
• Side effects: nausea, vomiting, diarrhea, pain in the epigastric region, allergic reactions. Treatment includes drinking plenty of water, taking antihistamines and B vitamins.
• Contraindications: hypersensitivity to the components of the drug, terminal stage of chronic renal failure. Not prescribed for patients under 1 month, with glucose-6-phosphotidehydrogenase deficiency and lactase deficiency. With special caution, it is prescribed during pregnancy and lactation, for patients with impaired renal function, liver and CNS diseases.
• Overdose: polyneuritis, toxic liver damage. Treatment includes gastric lavage, taking saline laxatives and enterosorbents. Measures to maintain water-electrolyte balance are also recommended.

Release form: tablets for oral administration, rectal and vaginal suppositories.

Furamag or Furadonin

Both drugs have antimicrobial properties and are effective in treating diseases of the genitourinary system. The drugs are available in tablet form. Furadonin has more contraindications and side effects. Each of the drugs is effective in treating bladder inflammation. The final decision on the choice of medication should be made by the attending physician.

Furamag is an antimicrobial agent from the nitrofuran group. Contains several active components: furazidin and magnesium carbonate. It is stable in the acidic environment of the stomach and changes the pH of urine, creating high concentrations in the kidneys. The active substances inhibit the synthesis of nucleic acids, destroying the membranes of pathogenic microorganisms, which leads to their death. It has a broad spectrum of antibacterial action.

• Indications for use: infectious and inflammatory diseases, cystitis, pyelonephritis, purulent wounds, purulent arthritis, gynecological infections. Burns, wound infections, sepsis, keratitis, conjunctivitis. Prevention of infectious complications in urological operations, catheterization.
• Method of administration: orally after meals, with water. Dosage for adults is 50-100 mg 3 times a day. The maximum daily dose is 600 mg. For children aged 1 to 10 years, 5 mg/kg per day is prescribed. The daily dose is divided into several doses. Duration of treatment is 7-10 days.
• Side effects: nausea, vomiting, headaches, allergic reactions. Long-term therapy leads to kidney and liver dysfunction.
• Contraindications: intolerance to the components of the drug, toxic hepatitis, polyneuritis. Pregnancy and lactation, terminal stage of chronic renal failure, patients under 1 month.
• Overdose: headaches, tinnitus, loss of appetite, allergic reactions. To normalize the condition, it is recommended to take antihistamines and enterosorbents, gastric lavage.

Release form: capsules for oral administration of 25 and 50 mg, 30 pieces per package.

Canephron or Furadonin

It is not advisable to compare these drugs by pharmacology. Furadonin has antibacterial properties, effectively destroys pathogenic flora and is suitable for the treatment of acute cystitis. Canephron has a herbal composition, is used for the complex treatment and prevention of inflammatory processes in the genitourinary system. It is allowed for pregnant women and children. In some treatment regimens, both drugs are prescribed, since Canephron is compatible with antimicrobial and antibacterial drugs.

Canephron is a medicinal product with anti-inflammatory and antispasmodic properties. It contains active substances of plant origin, which have a complex effect on the body: reduce the intensity of inflammation, eliminate spasms of the urinary tract and have a diuretic effect.

• Indications for use: acute and chronic infectious diseases of the kidneys and bladder, cystitis, pyelonephritis, glomerulonephritis, interstitial nephritis. Prevention of urinary calculi formation.
• Method of administration: orally, with plenty of liquid. The dosage and duration of treatment are determined by the attending physician, individually for each patient.
• Side effects: skin allergic reactions, nausea, vomiting, bowel disorders. In rare cases, acute urinary retention, urination disorders and blood in the urine occur. Overdose has similar symptoms, treatment is symptomatic.
• Contraindications: intolerance to the components of the drug, peptic ulcer in the period of relapse. Patients with cardiac or renal failure, renal dysfunction. Not used to treat children under 12 years of age. Allowed during pregnancy and lactation.

Release form: film-coated tablets for oral administration, 20 pieces per blister, 3 blisters per package.

Furadonin or Monural

Both medications have antibacterial and antimicrobial activity. Each of them can be a worthy alternative to the other. In severe cases of cystitis, both medications are prescribed for complex therapy of the disease.

Monural is a broad-spectrum antibacterial agent. Its active ingredient is fosfomycin trometamol. It has a bactericidal effect on most gram-positive and gram-negative microorganisms.

• Indications for use: acute and recurrent bacterial cystitis, massive asymptomatic bacteriuria in pregnant women, nonspecific bacterial urethritis. Prevention of bacterial infections of the urinary system during surgical or diagnostic manipulations. Infections of the urinary system in the postoperative period.
• Method of administration: orally, a sachet with granules of the drug is dissolved in 1/3 glass of water and drunk on an empty stomach. The drug is taken once. In case of recurrent diseases, the drug can be used twice.
• Side effects: nausea, vomiting, heartburn, allergic reactions. Overdose has similar signs, treatment is symptomatic.
• Contraindications: intolerance to the components of the drug, patients under 5 years of age, severe renal failure with creatinine clearance less than 10 ml per minute. Use during pregnancy is possible only on medical prescription.

Release form: 2 or 3 g sachet with granules for preparation of oral solution.

Furadonin or Nolitsin

Nolitsin is a fluoroquinolone antibiotic, and Furadonin is an antimicrobial agent. The drugs enhance each other's action, so they can be used to treat acute or chronic inflammation of the bladder.

Nolitsin is an antibacterial agent that creates high concentrations in urine. Contains the active component norfloxacin (quinolone group). It is active against gram-negative aerobes, as well as against strains of some gram-positive bacteria. Suppresses DNA gyrase enzymes in the cells of pathogenic microorganisms, disrupting the synthesis of bacterial DNA.

• Indications for use: upper and lower urinary tract infections, cystitis, chronic prostatitis, pyelonephritis, pyelitis, infections after urological operations, neurogenic bladder. Can be used in combination therapy for bacterial gastroenteritis and gonorrhea, as well as for the prevention of sepsis in patients with neutropenia.
• Method of administration: orally one hour before meals or 2-3 hours after. For cystitis, 400 mg is prescribed 2 times a day. Duration of treatment is 7-10 days. For recurrent chronic infections, the duration of therapy can be up to 12 weeks. Prophylactic dose is ½ tablet once a day for 4-6 months.
• Side effects: abdominal cramps, nausea, vomiting, bowel disorders. Headaches and dizziness, irritability, paresthesia, tremor of the extremities, allergic reactions. Leukopenia, thrombocytopenia, muscle pain, vaginal candidiasis.
• Contraindications: hypersensitivity to norfloxacin and other components of the drug, glucose-6-phosphate dehydrogenase deficiency, pediatric practice. Use during pregnancy and lactation is permitted.
• Overdose: diarrhea, nausea, vomiting, increased fatigue, convulsions. There is no specific antidote. Gastric lavage and enterosorbents are indicated for treatment.

Release form: tablets for oral administration, 10 pieces in a blister pack, 1-2 blisters per pack.

Nitroxoline or Furadonin

The pharmacological group of nitroxoline is 8-oxyquinoline derivatives, while Furadonin is a nitrofuran derivative. Both drugs have antimicrobial and antiparasitic activity. The decision on choosing a more effective remedy is made by a doctor, individually for each case.

An antibacterial agent, effective against gram-positive and gram-negative bacteria and some types of fungi.

• Indications for use: cystitis, pyelonephritis, urethritis, prostatitis and other urinary tract infections. Prevention of infections after operations on the urinary tract and kidneys.
• Method of administration: orally, during or after meals. The daily dosage for adults is 400 mg, divided into 3-4 doses per day. If necessary, the dosage is increased to 150-200 mg 3-4 times per day. The maximum daily dose is 800 mg. Duration of treatment is 2-3 weeks.
• The drug is contraindicated in case of intolerance to its components. Side effects are manifested by the following symptoms: nausea, vomiting, bowel disorders, changes in urine color.

Release form: enteric-coated tablets of 50 mg, 50 pieces per package.

Furadonin for cystitis, like all the above-mentioned drugs, should be taken as prescribed by a doctor, observing the dosage and duration of therapy.