Drops from alcoholism

Feelings of people whose relatives suffer from alcoholism can be understood only by those who have felt the entire horror of the situation. The difficulty also lies in the fact that mostly people burdened by alcoholism do not recognize this as a problem, insisting that if they wish they can easily quit drinking on their own. Therefore, relatives, trying to cure the patient on their own, try various methods, methods and medications. In this article, we will try to find out what drops of alcoholism modern pharmaceutical pharmacology offers to date, how effective and safe they are for a sick person's body.

[1], [2]

Indications for use of a drop of alcoholism

It is worth noting that the most stable result of any therapy largely depends on the mood of the patient, his desire to get rid of the problem. Therefore, if a drinking person realizes his misfortune and has a desire to stop craving for alcohol, then pharmacological agents will help him in this. But if the patient does not want to be treated independently, here the situation is more complicated. But do not sit still, idly, and expect when a close person completely sopetsya and lose his human face, and even life. You must try it!

Indications for use of drops from alcoholism are as follows:

• Directly treat alcoholism as a disease.
• Catching the symptoms of a hangover.
• Elimination of recurrence of the disease.
• Substitution therapy (aversive), which, by the introduction of certain drugs, produces a "replacement" of the feeling of pleasure from the accepted spill of alcohol for aversion to the drink.

Alcoholism is accompanied by the corresponding symptomatology:

• Strong pain in the head.
• Increased irritability.
• Depressive states.
• Apathy or, conversely, aggression.
• An excessive sense of anxiety.
• Loss of appetite.
• Sleep disturbances.
• Quick change of mood.
• Emotional instability.

Form of issue

Medicines that have the pharmacodynamics of interest are presented in the modern market quite widely. Their form of release is also different. These are tablets, solutions for injections. Widely used and the drops taken by the patient orally.

The drop form is also good because, without the color, taste and smell, it allows to enter them into drinks and food of the alcoholic, without his knowledge. Usually drops that can be easily purchased in any pharmacy are bottled with dark glass bottles. The volume of the produced drug is mainly 25 ml, but on the shelves of pharmacies, you can find and dosage in 50 ml. The bottle is placed in a cardboard box and is equipped with instructions for use.

The composition of medicines naturally has its own characteristics and differences.

[3], [4], [5]

Pharmacodynamics

To date, pharmacological companies produce drops from alcoholism of three types, which differ somewhat in the result of the action:

• Pharmacodynamics alone allows you to cause the patient to aversion to alcohol.
• Others are more effective in reducing the sense of need to drink, and relieve the severe symptoms of a hangover.
• The third category is those that are designed to cause alcohol intolerance to varying degrees.

When the drug is injected into the body of a drinking person, the synthesis of acetaldehyde dehydrogenase, a hepatic enzyme, that suppresses the oxidation of acetaldehyde, is suppressed.

In case of getting into the body even a small amount of alcohol, the oxidation process takes place more actively, cumulating the products of the result of transformation in the body, which invariably leads to alcohol intoxication, and, in fact, to poisoning.

The active ingredient, the drug used, inhibits this enzyme, and the chemical compound cyanamide activates the synthesis of acetaldehyde, which is the metabolite of ethyl alcohol.

Such processes can cause a negative reaction of the organism, manifested by uncomfortable symptoms.

This happens immediately after a person who suffers alcoholism, at least drink a small amount of an alcoholic beverage. The person begins to experience:

• The respite.
• Cardiopalmus.
• A sharp rush of blood to the head.
• Nausea.
• Tremor.
• Desires for vomiting.

The admission of the group of drugs under consideration makes it possible to cause the patient to dislike not only the taste of "fiery fluid", but also the smell of alcohol-containing beverages. This reflex is formed at the level of the subcortex of the brain.

It is worth noting that the hypotensive effect is not observed when cyanamide is administered, whereas disulfiram provokes its development. The therapeutic effect after getting the drug into the body of a drinking person comes in 45 minutes - an hour. At the same time, its effect does not weaken over the next 12 hours.

Almost all drugs, getting into the body, begin to influence, including, the fate of the cerebral cortex (hypothalamus, hippocampus and others), which are responsible for fixing the body's resistance, strengthening the patient's ability to resist the toxins that come with alcohol and "tearing" the formed dependence from alcohol.

The drug of this group modifies the functional activity of protein S-100, which "connects" the information entering the brain and those processes that occur in the body. They increase the sensitivity of the neuronal membrane to the effects of stimuli. The work of renal neurons in the hippocampus is somewhat reduced, which leads to a decrease in the quantitative component of the immune complexes that circulate along with the peripheral blood. This fact makes it possible to reduce the necessary body requirement for ethanol, weakening cravings for alcohol. Allow to restore and normalize the synaptic plasticity of neurons.

These drugs are a catalyst for positive psychological reinforcement of the recovery process, which is one of the main keys to achieving positive results, allowing to reduce the need for alcohol to stimulate the lateral hypothalamus.

The carried out researches have shown that preparations of the considered category of medical products restore conditionally reflex connections, normalizing the neurotransmitter balance, and also strengthen the stability of the organism as a whole, and the brain in particular, to toxins and hypoxia.

Pharmacokinetics

Large-scale studies to determine the characteristics of interest have not been carried out, but some data related to the section under consideration are still available. The pharmacokinetics of drops from alcohol indicates that cyanamide, which is part of their composition, is fairly well absorbed into the plasma, showing a bioavailability of about 70%. The parameters of its total plasma clearance, depending on the individual characteristics of the patient's body, falls within a limit of 42 to 62 minutes.

Names of drops from alcoholism

As already noted, an essential bonus in obtaining the desired result is the desire of the person who drinks. But even if he does not receive consent for treatment, fight for his life, and the quality of life of his associates, it is necessary. Therefore, relatives, secretly from the alcoholic, begin to add anti-alcohol droplets to him in drinks or meals.

With each day of drugs with this effect on the shelves of pharmacies is becoming more. Therefore, one should recall at least some names of drops from alcoholism and get acquainted with their characteristics.

In any modern pharmacy today you can find such drugs: proproten-100, vitale, anti-ethyl, disulfiram, esperal, caprinol, stopitil, colme, tetura and many others.

For example, teturam, an active active substance, which is disulfiram (disulfiramum), is ingested orally. The therapeutic dosage is selected for each patient individually in the range from 0.25 to 0.5 g per day. Doses, below the recommended drugs, are very quickly eliminated from the body, without showing any significant effect.

Vital is a dietary supplement made on the basis of a complex of medicinal herbs. It is necessary to approach the issue of treatment with all responsibility. The drug is administered taking into account the patient's concomitant diseases, as well as the duration of alcoholism and the degree of alcohol dependence. This drug is perfectly combined with food, which makes it possible, even without the knowledge of the patient, to mix it with food and drinks (including alcohol itself). Before use, the contents of the vial must be shaken several times.

Lavital - this drug is used both for relief of the problem of alcoholism, and for its prevention. Its basis is medicinal herbs: hawthorn, green tea, motherwort, milk thistle, oregano, St. John's wort, dandelion root, thyme. Additionally, the composition contains glycine and succinic acid. When treating the disease in question, you must be patient. This drug is available in the form of drops, and in the form of syrup.

Usually the recovery process takes several months.

Colme

In more detail, we will focus on those products that are currently the most popular consumer. One of them - drops from alcoholism kolma. In their composition, you can find cyanamide - the main active substance of the drug. As well as sodium acetate, sorbic and acetic acids, water, which are additional chemical compounds.

The pharmacodynamics of cyanamide has already been described above. It interferes with the synthesis of acetaldehyde hydrogenase, which takes a direct part in the processing of ethyl alcohol. With a decrease in the production of the enzyme, there is an accumulation of unprocessed acetaldehyde, which is a product of the cleavage of alcohol, which leads to intoxication of the alcoholic organism.

It is this reaction that provokes the appearance of a severe hangover, associated with the pathological symptoms described above. And as a result - every intake of alcohol begins to be accompanied by a strong discomfort, which produces a persistent rejection of alcohol in a person, and the emergence of a conditioned reflex aversion to the smell and taste of alcohol.

The positive aspects of taking this medication include:

• A relatively small percentage of relapses (subsequent disruptions).
• The drug is safe for the patient's body during long-term admission.
• Promotes the normalization of appetite and general (both physical and emotional) tone, which is important in this situation.

The daily recommended amount of the drug, depending on the individual characteristics of the human body, its condition and the severity of the disease, is from 35 to 75 mg, which corresponds to 12 to 25 drops taken once or twice throughout the day.

The drug has no smell or taste, which makes it possible to use it for therapy and without the knowledge of a person who drinks.

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Barrier

Another drug that allows you to stop the problem without any serious consequences is a drop from the alcohol barrier. This drug belongs to the drugs of the new generation and is not so "popular" with the consumer, but already has quite enthusiastic reviews.

This parapharmaceutical allows you to more easily abandon the emotional and physical craving for alcohol. His work is to reduce the pathological effects of ethanol on the patient's body. It favorably affects the metabolic processes, restoring their normal work. This drug gives a stable result before alcohol.

In addition, the antialcoholic agent normalizes the functions of the central nervous system, reduces the intensity of the manifestation of hangover syndrome.

The barrier is produced in the form of drops. The liquid has no smell, the shade is brown, transparent. The duration of therapy is on average three weeks.

The considered drops are convenient in that their use goes unnoticed for drinking people. Close alcoholics can easily inject them into drinks and food without fear of being "caught" on it. The only caveat: a dish in which the drug is mixed should be dark (because of the shade of drops). After all, on light meals they will be noticeable.

A week after starting treatment, others should notice the first results of therapy. The craving for alcoholic alcoholic should decrease.

This drug has virtually no contraindications, which extends its use even for people belonging to a certain category of patients who have limitations in taking other drugs of this pharmacological group. But this absolutely does not mean that the medicine can be prescribed independently and used uncontrolled. Consultation specialist should be required. It is he who will help determine the dosage of the drug, and with its injection schedule.

[8], [9]

Proproten 100

Another sufficiently popular drug - drops are proproten 100 from alcoholism, which, being a homeopathic remedy, are released in droplets form and in the form of tablets. This drug is mainly used to relieve the hangover symptoms: headache, emotional stress, digestive problems, anxiety, sleep problems.

If the question of treatment of alcoholism is raised, then this drug should preferably be taken not as monotherapy, but in combination with other drugs.

The main function is proproten 100 - this is to weaken the negative symptoms of a hangover. This drug is suitable for people who do not suffer from alcoholism, but who are demented after a "plentiful feast" the day before.

Drug medicines are recommended to apply minutes for fifteen to twenty to the intended meal. Drops, like the tablet form, should not be swallowed immediately. It is necessary to hold the drug in your mouth for some time. This will allow it to dissolve.

If physicians observe a sharp form of an absurdity syndrome, then the medicine is injected into the patient's body every half hour by one tablet or the appropriate dosage in drops (one tablet - 15 drops). Gradually, the interval is increased to two hours. At night, the reception is stopped, and in the morning the circuit is repeated. If the therapeutic effect is achieved, then the interval between doses is maintained at three o'clock - this regime is followed for three days, then goes to the regime - two tablets (or a corresponding amount in drops) once a day for a month.

Coprinol

It is worth remembering and another drug, related to the drugs of the group under consideration - droplets of koprinol from alcoholism. This is a relatively expensive, but effective medicine of the new generation. Some refer them to vitamin complexes, others - to dietary supplements.

To date, it does not occur in retail sales, but is distributed by specialized firms. In the instructions attached to the drug, it is indicated that it is made from the extract of the fungus of the dung, which from time immemorial alternative healers treated those who often looked into the glass. There are also succinic acid and vitamins.

The work of the drug koprinola is aimed at causing a drinking person to aversion to alcohol-containing beverages. But taking this medication should be done under the supervision of a specialist without self-medication, since coprinol is characterized by a rather high aggressiveness and detrimental to the liver of the patient, destroying its structures.

The recommended dosage is 2 ml, which is mixed in the drinks and food of the patient. Doctors strongly recommend during treatment categorically refuse to drink alcohol. This will at least partially reduce the stress of internal organs on the drug. It is not superfluous to connect the vitamin and mineral complex and healthy food.

Adding drops from alcoholism to food

The modern pharmacological market is ready to offer a wide range of anti-alcohol medicines. But often the problem is not even their high or low efficiency, but the fact that most people suffering from alcoholism do not see this as a problem. They are fully confident that they will quit drinking with ease as soon as they want. This is the whole problem. Therefore, the alcoholic's relatives and friends have to try many different drugs and drugs to positively solve the problem.

One of the ways out in this situation can be called drip-on drops from alcoholism, which allow you to guide the treatment course, in secret from the patient himself.

The form of the medicine in the drops is convenient because the liquid has neither taste nor smell. This allows you to "mask" the drug with your favorite food of the alcoholic. In this case, drops can be taken for a fairly long time, since they do not have a significant negative effect on the internal organs of the alcoholic, including the liver.

But this advantage is worth the money. And as we show monitoring the prices of these drugs, the drops cost a little more than the tablet form, so buyers tend to buy tablets more often.

Of course, the treatment channels with anti-alcohol tablets bring certain positive benefits, but it is worth noting that many patients simply can not stand the long course of influence of tablets on the body (their high toxicity) and break down into drinking.

Choosing the form of medicines, it is worth considering all aspects of the problem and in some cases choosing a more expensive but effective drug is not a waste, but a direct saving. But it should also be remembered about possible side effects that may occur against the background of the drug being administered.

Many medical workers believe that it is impossible to forcibly treat a patient, because such an approach can be dangerous for an alcoholic. Therefore, any treatment should be approved by a qualified specialist and under his supervision. It is desirable to try to convince a drinking person of the need to seek help from a narcologist and only through joint efforts to try to cope with the disaster.

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Dosing and Administration

If the problem in question arises and one of the familiar or close people "rolls on an inclined" one, one should try to persuade him to seek help from a specialist. Only a narcologist who examines the patient will prescribe to him the most effective drug that corresponds to his clinical picture and the condition of the body at the time of seeking help.

In this case, the most effective way of applying and dose of the drug, the schedule of treatment will be prescribed. These facts differ depending on the status of the person and the medicinal product that was prescribed to him.

If you can not consult the doctor, then the precautions described in the instructions accompanying the drug should be followed strictly. This will reduce the risk of side effects and serious complications.

If the alcoholic does not know that he is being treated, then a situation may arise when latent intoxication develops, which, if the patient is dysregulated or has a history of liver, kidney and cardiovascular disease, can lead to death.

If serious health problems are not observed in the patient, the duration of the treatment course is about three months, and the amount of medication administered varies from 15 to 30 drops per administration. Usually such inputs are made by two during the day. Since most drugs show a sufficient level of therapeutic efficacy for 12 hours, it is this interval that is maintained in the drug intake.

It is best to inject the medicine into warm dishes or drinks. The only exception is alcohol containing liquids, which should not be allowed into the patient's diet.

This duration of therapy is conditioned by the necessity of forming a conditioned reflex on alcohol.

Some drops should be taken half an hour before meals. In this case, you should take them together in some liquid (enough 15 - 20 ml of water), and after 30 minutes eat. For example, 100 isproproten is introduced in an amount of 10 drops. If the result of injecting the drug is to remove the hangover syndrome, then the reception schedule is the same: the first 2 hours - the administration of the drug every 30 minutes, then - every hour, until the removal of negative symptoms.

As a prophylactic agent, 100 is taken in the same dosage, but one or two injections throughout the day.

If heavy alcohol abstinence is observed, these drops are injected into the complex therapy that conducts detoxification of the alcoholic.

[12], [13], [14], [15]

Use of drops from alcoholism during pregnancy

Drugs of the pharmacological focus are quite "aggressive", in addition, they have not yet been sufficiently investigated for effects on the developing embryo. Therefore, the use of drops from alcoholism during pregnancy and at a time when a young mother feeds her newborn baby with breast milk is categorically not permissible, although, frankly speaking, alcohol and pregnancy are also two medically incompatible statuses.

Contraindications to the use of drops from alcoholism

In connection with its pharmacological features and systemic impact, there are also contraindications to the use of drops from alcoholism, which are indicated below listed pathologies and human status:

• Individual intolerance to the patient's body of one or more components of the drug, including cyanamide.
• Pregnancy and lactation.
• Congenital lactase insufficiency.
• Propensity to allergic reactions.
• A strong stage of alcohol intoxication, followed by severe intoxication.
• Diseases of the thyroid gland.
• Moderate or severe dysfunction of the liver and / or heart.
• Symptomatic of "white fever". Severe mental disorders.
• Pathology of the vascular system.
• Diseases of the respiratory system.
• The possibility of an epileptic seizure.
• Diabetes mellitus and other diseases associated with impaired metabolic processes.
• Congenital galactosemia.
• Severe form of kidney failure.
• Oncological diseases.
• Malabsorption of glucose.
• The patient's old age (if he is over 65 years old).

There is also a rather insignificant effectiveness of drugs, in case of neglected form of alcoholism. The course of treatment with the drugs in question is able to help achieve the expected result, only with alcoholism of the first or second stage.

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Side effects of drops from alcoholism

The preparations of the pharmacological group under consideration show a good tolerance of the patient's body, but the side effects of drops from alcoholism, however, in some cases were manifested and documented. Especially the risk of developing pathological symptoms increases if, against the background of treatment, the patient "takes on the chest" even a small amount of alcohol.

The consequences of such a connection can manifest like this:

• Spontaneous rush of blood to the head, expressed reddening of the skin of the patient's face.
• Increase in blood pressure, which even begins to be felt by an increase in the pulsation of blood vessels located in the cervical region and head.
• There is a slight drowsiness.
• A breathing problem may occur.
• There are bouts of nausea, reaching the vomiting reflex.
• Decreased efficiency.
• Decrease in the general tone of the body.
• Fast fatiguability.
• There may be pain in the chest area.
• Decreased visual acuity.
• Emotional instability is expressed by panic attacks and fear.

It should be clarified once again that this symptomatology appears in the case when the patient continues to consume alcohol against the background of therapy and disappears after the introduction of alcohol ceases.

Overdose

A single picture, which would cause an overdose of drugs against alcoholism, today is not described. Doctors - drug addicts suggest that it is quite possible to exacerbate the symptoms that arise as a side effect of the introduction of certain drugs of this pharmacodynamics. Therefore, in detecting pathological symptoms, antisymptomatic therapy is needed to support the normal functioning of the heart and the respiratory system. In especially severe cases, a blood transfusion is necessary - hemodialysis.

Interactions with other drugs

It is difficult to unambiguously talk about the results of interaction with other drugs of antialcoholic medicines, as a number of them behave fairly neutrally with drugs from other pharmacological groups. But there are also those that should be introduced with great care into the comprehensive treatment protocol.

For example, the Colme drug should not be administered in conjunction with preparations of the aldehyde group. These include drugs that contain paraldehydes or chloral products.

In the same way, the administration of such a drug as disulfiram should be disrupted. The interval between the courses of kolma and disulfiram should be at least ten days.

Against the background of anti-alcohol therapy should not prescribe drugs that can strengthen cravings for alcohol. For example: metronidazole, isoniazid, phenytoin.

And, accordingly, do not take medications, which include ethyl alcohol.

Storage conditions

Each company-developer produces any drug with accompanying instruction, in which the storage conditions of this preparation are described. They must be carried out rigorously. This will preserve the high pharmacological effectiveness of the drug throughout the life of the product.

Storage of drugs in this category requires:

• The storage place must be protected from direct sunlight and moisture.
• Should not be available for children.
• The temperature at which the medicine is stored should be in the range from 15 to 25 ºС.

Shelf life

The shelf life of the drugs in this group is basically two years (24 months). At the same time, the date of issue and the deadline for implementation are mandatory on the packaging. If the end date is overdue, further use of the medicinal product is not permissible.

Alcoholism is a great grief in the family and it affects not only the person suffering from this disease, but all its members. To struggle with this problem and the more difficult the harder the alcoholic tries to ignore his problem. But to save a loved one is necessary. And this can help drop from alcoholism. It is only necessary to recall that the independent appointment of a given drug can end very badly. Cases of even a lethal outcome are known. Therefore, before deciding on therapy, you should try to persuade the patient to seek help from a narcologist. If this is not possible, then a consultation must pass through to someone from the neighbors. The doctor, on the basis of the medical chart of the drinking person, will try to give the necessary recommendations. The main thing is not to give up, but to fight.