Antibiotics for acute cystitis

An obligatory component of medicamental treatment of inflammation of the bladder is antibiotics. The need for these drugs is caused by the infectious nature of the disease. The choice of the drug, its dosage and the duration of therapy are determined by the attending physician after a laboratory test for the causative agent of the infection and its sensitivity to antibacterial agents.

Modern antimicrobial agents allow you to quickly cope with unpleasant symptoms of inflammation and destroy pathogens after the first application. In acute cystitis, antibiotics are used:

1. Nigram

Antimicrobial preparation, uroantiseptic from the pharmacological group of quinolones. It is active against Shigella spp., Proteus spp., Escherichia coli, Salmonella spp., Klebsiella spp., And strains resistant to sulfonamides and antibacterial agents. Depending on the concentration of pathogenic microorganisms and their sensitivity to the drug, it exhibits bacteriostatic or bactericidal action. It stops the process of polymerization of bacterial DNA, stopping its synthesis.

• Indications for use: infectious and inflammatory diseases of the genitourinary system in acute and chronic form. Antibiotic is effective in cystitis, urethritis, urethral syndrome, pyelonephritis, inflammation of the prostate. It is prescribed for gastrointestinal infections, cholecystitis, as well as for the prevention of infectious complications during surgical manipulations on the bladder, ureters, kidneys.
• Directions: Orally 1 g every 6 hours for 5-7 days. The maintenance dosage is 500 mg 3-4 times a day. The maximum daily dose is 4 g, in especially severe cases it can be increased to 6 g.
• Side effects: increased weakness, drowsiness, headaches, visual impairment and color perception, dysphoria. Nausea, vomiting, diarrhea, gastrointestinal bleeding, allergic reactions.
• Contraindications: hypersensitivity to the components of the drug, pregnancy and lactation, patients younger than 2 years, atherosclerosis of the cerebral vessels, renal / hepatic insufficiency, epilepsy, deficiency of glucose-6-phosphate dehydrogenase.
• Overdose: increased adverse reactions, convulsions, psychotic seizures, metabolic acidosis, confusion. For treatment symptomatic therapy with gastric lavage 3% sodium bicarbonate solution is indicated.

Product: tablets for oral administration of 500 mg, 56 pieces per package.

2. Nitroxoline

It shows antibacterial action against gram-positive and gram-negative microorganisms, some fungi. After oral intake quickly absorbed from the digestive tract, is excreted unchanged by the kidneys, creating high concentrations in urine.

• Indications for use: inflammation of the bladder, pyelonephritis, urethritis, prostatitis and other infections of the urinary tract. Prevention of infectious complications after operations on the kidney and urinary tract. Diseases caused by microorganisms that are sensitive to the drug.
• Method of administration: orally, during or after a meal. The average daily dosage for adults is 400 mg, divided into 4 divided doses. If necessary, the dosage can be doubled. The duration of treatment depends on the severity of the disease state, so it is individual for each patient.
• Side effects: dyspeptic disorders, allergic rashes. In patients with renal insufficiency, it is possible to accumulate the drug in the body and color the urine into a saffron-yellow color. Overdosing is manifested by increased adverse reactions. There is no specific antidote, treatment is symptomatic.
• Contraindications: intolerance to 8-hydroxyquinoline derivatives.

Form release: tablets with enteric coating of 50 mg, 50 pieces per package.

3. Palin

Antibacterial agent used in the treatment of urological and gynecological diseases. Contains the active ingredient from the group of quinolone series with pronounced bactericidal and bacteriostatic properties - pipemidic acid. Palin shows activity against gram-negative and gram-positive microorganisms. Resistance to the drug develops slowly.

• Indications for use: diseases of the urinary tract and bladder caused by microorganisms sensitive to the preparation. Prevention of recurrent urinary tract infections. Complex therapy of vaginal infections.
• Directions for use: by mouth, regardless of food intake, with plenty of water. Adults appoint 400 mg twice a day. The duration of treatment depends on the severity of the disease state, but usually does not exceed 10 days.
• Side effects: nausea, vomiting, decreased appetite, heartburn, flatulence, pseudomembranous colitis. Also, there are possible violations on the part of the hematopoiesis system and the central nervous system, allergic reactions, development of superinfection.
• Contraindications: intolerance of the components of the drug and drugs from the group of quinolones. Pregnancy and lactation, patients younger than 15 years. With special care is prescribed for patients with epilepsy, propensity to convulsive seizures, porphyria, deficiency of glucose-6-phosphate dehydrogenase.
• Overdose: headaches and dizziness, nausea, vomiting, tremor of limbs, confusion, convulsions. There is no specific antidote, treatment is symptomatic, hemodialysis and Diazepam administration are possible.

Form release: capsules for oral administration of 10 pieces in a blister, 2 blisters per package.

4. Rollid

Antibacterial agent from the group of macrolides with the active component - roxithromycin. It has a wide spectrum of antibacterial activity and low toxicity. Affects streptococci, staphylococcus, listeria, meningococcus, chlamydia, mycoplasma, ureaplasma and other pathogens.

• Indications for use: infections of the urinary and urogenital system, staphylococcal infections, pneumonia, scarlet fever, sinusitis, tonsillitis, diphtheria, pertussis, soft tissue infections. Urethritis, bronchitis, bacterial infections in COPD, vaginitis, odontological infectious diseases, genital infections.
• Method of application: for patients with a body weight of more than 40 kg, the daily dose is 300 mg. With renal failure take 150 mg once. Duration of treatment - 5 or more days. Tablets are taken orally, before meals, with plenty of water.
• Side effects: nausea, vomiting, diarrhea, epigastric pain, angioedema, cross-resistance, headaches and dizziness, skin allergic reactions, bronchospasm, superinfectious complications. Overdose is manifested by increased side effects. Specific antidote is absent, treatment is symptomatic with gastric lavage.
• Contraindications: intolerance of the components of the drug, pregnancy and lactation.

Product: tablets for oral administration of 10 pieces per package.

5. Suprax

Antibiotic from the group of cephalosporins of the third generation for parenteral use. It has a bactericidal effect and has a wide spectrum of action against aerobic and anaerobic gram-positive, gram-negative microorganisms.

• Indications for use: uncomplicated urinary tract infections, gonococcal urethra and cervical infection, pharyngitis, tonsillitis, sinusitis, acute and chronic bronchitis, otitis media and other infectious and inflammatory diseases caused by microorganisms sensitive to the drug.
• Method of application: for adults and children over 12 years of age with a body weight of more than 50 kg, a daily dosage of 400 mg divided into two doses. The duration of treatment depends on the severity of the disease state and is set individually for each patient.
• Side effects: allergic reactions, renal dysfunction, interstitial nephritis, vaginitis, nausea, vomiting, stomatitis, leukopenia, hemolytic anemia, dizziness and headaches. Overdose has a similar symptomatology. For treatment, gastric lavage, hemodialysis and peritoneal dialysis are ineffective.
• Contraindications: intolerance to the components of the drug, the age of patients younger than 6 months, pregnancy and lactation. With special care is prescribed for elderly patients and with kidney failure.

Form release: capsules for oral administration of 200 and 400 mg of 6 pieces per package. Granules for the preparation of suspensions and suspension for oral administration 60 ml.