Pills from poisoning

Poisoning is an acute or chronic toxic damage to the body resulting from exposure to chemicals or toxins from microorganisms. Intoxication leads to disruption of vital vital functions of various organs and systems. Classify the poisoning depending on the cause and place of the introduction of the poison compound, the way the hit substance enters the human body, the duration of the exposure and the degree of manifestation of clinical symptoms.

The main classification groups are :

• Reason and location of the poisonous substance: random, intentional, suicidal, criminal, industrial, domestic. The most common is the household group: the use of low-quality food, alcohol, drugs, drug overdose, the result of self-treatment, etc.
• The way of getting the injuring compound: oral (household group), inhalation (the result of the inhalation of the poison agent), the ingestion of poisons through the skin and mucous membranes (bites of poisonous snakes, insects or the skin of secretions of poisonous animals).
• Duration of exposure to a poisonous substance: acute and chronic poisoning. Acute poisoning occurs with a single hit of a toxic compound and a sharp occurrence of the corresponding symptomatology. Chronic damage is detected with the accumulation of toxins in the body and is characterized by a gradual increase in the symptoms of poisoning with frequent ingestion of subtoxic doses for a long period.

Degree of toxic damage: mild, moderate, severe and critically severe.

Among food poisoning, food-borne diseases are leading. Occur when eating infected and poor-quality food. Characterized by a sudden onset (the first signs appear after 2-6 hours after the introduction of the pathogen) and a sharp increase in the severity of the symptoms. The main manifestations: weakness, malaise, nausea, repeated vomiting, chills, fever, flatulence, diarrhea. Such manifestations require urgent consultation of a specialist or emergency hospitalization in a medical institution.

The initial stage of therapy is to evacuate the remains of toxic foods from the upper intestine. Do this with the help of the procedure for washing the stomach and applying enterosorbents. The first washings are subject to collection for bacteriological inoculation and detection of a pathogen of poisoning.

[1], [2], [3]

Dosing and administration

Tablets from poisoning are divided into:

• Sorption drugs (activated carbon, filter, polysorb) are able to bind substances that poison the body directly in the intestines, preventing the introduction of toxins into the systemic bloodstream. Excretion, formed during the absorption of compounds, occurs together with the calves.
• Activating bowel motility (motillium, metoclopromide), accelerate the process of evacuation of absorbed components. Metoclopromide is used for the symptomatic relief of nausea and vomiting.
• Antibiotics of a wide spectrum of action (enterofuril, levomitsetin, tetracycline, furozolidone), to combat bacterial flora. Obtaining the result of bacterial wash water may entail the administration of drugs used to eliminate a particular pathogen of poisoning.
• To restore the disturbed balance of the intestinal microflora after the introduction of the causative agent of OCI and the use of antibacterial drugs, probiotics (hilak forte) are prescribed.

[4], [5], [6], [7], [8]

Activated carbon

The drug Activated charcoal is the most simple, effective and cheap tablets against poisoning. Sorbent is made from specially treated coal of vegetable or animal origin. The drug has an excellent absorbing effect, absorbing gases, alkaloids (nitrogen-containing substances), toxins.

Pharmacodynamics. A powerful sorbent. Absorption capacity extends to the entire surface of the drug. Reduces absorption from the lumen of the gastrointestinal tract toxins, poisons, heavy metal salts, glycosides and alkaloids of medicines, helping to reduce their concentration and evacuation from the body. Sorption capacity is also maintained with respect to gases.

Pharmacokinetics. The drug does not penetrate into the blood through the lumen of the gastrointestinal tract and is not subjected to metabolic transformation. Time of passage through the intestine is 25 hours. Evacuated with unhealthy masses.

Method of application. Tablets or powder for oral use should be drunk with sufficient water.

In acute forms of poisoning for gastric lavage, a slurry prepared from water and activated charcoal powder (it can be obtained by grinding tablets) is used. The patient is then given an oral tablet intake of 20-30 grams per day.

With flatulence and dyspeptic manifestations, the drug is prescribed for 1-2 grams 3-4 rub. / Day. Within 3-7 days. In each case, the individual duration of the course of use of enterosorbent is determined by the doctor.

The use of activated carbon is associated with the diet and the pattern of use of other drugs. Synchronous use of sorbent with other drugs significantly reduces their effectiveness. Coal tablets are taken 60 minutes before meals or oral medications and 1.5-2 hours thereafter.

Long-term intake of the sorbent can reduce the level of minerals, vitamins, causing violations of the acid-electrolyte balance of the body.

Application during pregnancy. The use of activated carbon is allowed on all terms of the gestational period. At the expressed phenomena of a toxicosis can be appointed or nominated by the doctor with the purpose of simplification of a status of the pregnant woman. Do not abuse the use of sorbent, since the supply to the body of useful minerals and vitamins is slowed down. Use of activated carbon during pregnancy is possible only in case of emergency with the permission of the doctor.

Interaction with other drugs. Reduces absorption and activity of drugs in synchronous use.

Contraindications. Individual intolerance, the presence and period of exacerbation from any part of the gastrointestinal tract, intestinal atony, children under 6 years of age.

Side effects. The use of activated charcoal causes dyspepsia, difficulty in defecation, staining of stools in black. Long-term use leads to a decrease in the level of vitamins, microelements and nutrient compounds.

Form release - tablets, granules and powder of black color without taste and smell.

Storage conditions. Dry place inaccessible to sunlight. Keep in sealed packaging separately from preparations that emit fumes and gases. Excessive humidity leads to a decrease in absorption capacity. Shelf life is 3 years.

[9], [10], [11]

Filter

Sorbent of natural origin. Produced in the form of tablets and lozenges. The active ingredient is hydrolytic lignin. It is a universal sorbent with a high absorption capacity. It binds toxic substances in the intestinal lumen and prevents their harmful effects on the body. It is used in a complex of detoxification activities for poisoning caused by various causes and substances. Helps reduce the concentration and excretion of absorbed toxins with feces, activating the normalization of physiological processes of the intestine.

Use of tablets against poisoning during pregnancy. Studies on the effect of the drug on the body of a woman during gestation were not conducted. There are no scientific data on the harmlessness of Filtrum for pregnant women.

Contraindications :

• Hypersensitivity to the active ingredient of the drug;
• Presence in the anamnesis or a stage of an exacerbation of ulcerative lesions of various departments of an intestine;
• Gastrointestinal bleeding;
• Atony of the intestine;
• Obstruction of any of the digestive tract;
• Galactosemia.

Side effects. The drug is able to cause allergic reactions with individual intolerance of the components. Reception Filtrum, regardless of the form of release can provoke the appearance of flatulence. Often on the background of taking the drug constipation occurs. Long-term use leads to a decrease in the level of vitamins and minerals in the body. Simultaneous application of Filtrum with other drugs significantly reduces their therapeutic effect.

Method and dosage of tablets against poisoning. The dosage of tablets depends on the age category, the patient's body weight and the severity of the poisoning. The number of tablets and the scheme of their reception is determined by the attending physician. The average therapeutic dose of a single dose is: for adults - 2-3 tab., For children from birth to 3 years - 0.5 tab., For children 4-7 years - 1 tab., For children 7-12 years - 1 -2 tab. Sorbent from poisoning should be taken 3-4 times a day. The maximum daily dosage is 50 tablets. The filter is taken orally for 60 minutes. Before eating or taking other medications. It is desirable to grind the tablets, prepare a suspension. Therapy in the acute period of poisoning lasts 3-5 days.

Overdose. Cases of overdose are not fixed.

Interactions with other drugs. Reduces the therapeutic effect of other medications in a synchronous reception. Long-term courses of treatment with sorbent should be accompanied by the intake of various vitamin-mineral complexes.

Storage conditions. Dark, dry place. Keep away from children. Keep hermetically sealed away from preparations with strong odors.

The expiration date is indicated on the blister, as well as the factory carton packing and is 2 years.

[12], [13]

Polysorb

Synthetic siliceous preparation is a powerful enterosorbent. Produced in the form of a powder for the preparation of a suspension used orally.

Pharmacodynamics. Has an absorbent and detoxifying effects. It binds and eliminates toxic compounds of various genesis (bacterial endotoxins, poisons, salts of heavy metals, etc.) from the lumen of the gastrointestinal tract. It has a powerful sorption capacity.

Pharmacokinetics. The drug is taken orally in the form of a suspension. Polysorb is not subjected to metabolic transformations, it is resistant to changes under the action of enzymes and does not penetrate into the bloodstream. Evacuated with feces in unchanged form.

Contraindications. Increased hypersensitivity to the drug, erosive-ulcerative destructive pathology of the intestinal tract during exacerbation, gastric or intestinal bleeding, impaired intestinal motility.

Side effects. Individual allergic reactions to the main active substance are possible. Constipation. Continuous use leads to increased elimination of calcium, microelements and vitamins.

Method of application and dose of powder from poisoning. The poisoning therapy can begin with a gastric lavage using a Polysorb suspension. For this procedure, the concentration of the drug should be 0.5-1%. In parallel, the sorbent is administered inside. Dosage to adult patients is prescribed at a rate of 10-15 mg / kg body weight.

Overdose. The facts of drug overdose Polysorb are not fixed. It is not recommended to use sorbent in combination with other drugs, as it significantly reduces their effectiveness.

Store in sealed containers, in a dry place inaccessible to sunlight, with an air temperature not exceeding 25 ° C. Keep away from children. Shelf life is 5 years.

Together with the appointment of active sorbents in the treatment of food-borne infections, antibacterial agents of a wide spectrum of action are used. A prerequisite that requires compulsory compliance is the intake of drugs at different times to avoid inactivating the antibiotic.

Enterofuryl

Intestinal antimicrobial preparation, antidiarrheal action. The active ingredient is nifuroxazide. In the pharmacy network is implemented in the form of capsules (100 mg and 200 mg) or suspension for oral administration.

Pharmacodynamics. Enterofuril is an antibacterial agent that acts in the lumen of the intestine. Inhibits the growth and reproduction of pathogenic microflora. Creates high concentrations in the intestines, is not metabolized by the action of enzymes of the gastrointestinal tract.

Pharmacokinetics. Getting into the stomach is not absorbed by the gastrointestinal tract and shows an antibacterial effect exclusively in the lumen of the intestine. Eliminated unchanged with feces. The rate of excretion is dependent on the dose of the drug and the intestinal motility.

Pregnancy and lactation. The decision on the appointment of Enterofuril in these periods is made by the attending physician. Self-medication can have unpredictable and dangerous consequences. The use of capsules is permitted during the gestational period, if the benefit to the mother exceeds the possible risks for the unborn child. The drug in the lactation period is used in case of emergency.

Contraindications to the ingestion of Enterofuril capsules are:

• Hyperensitivity to nifuroxazide, the drug's adjuvants;
• Malabsorption syndrome.
• Deep prematurity and children under 1 month.

Side effects : nausea, vomiting; Allergic reactions (rashes, itching, angioedema) are extremely rare, but it is impossible to exclude their appearance from the list of side effects.

The way of application and dose of Enterofuril capsules from poisoning. Capsules are recommended for children from the age of 7 years. For children younger than 7 years of age, the use of a suspension is recommended. Capsules are swallowed whole, not liquid, without opening the gelatinous membrane and not pouring out the contents. Standard therapy lasts from 2 to 7 days. The duration of the drug is regulated by the doctor, depending on the severity and dynamics of the course of the disease

Children over the age of seven and adults - 200 mg four times a day, the maximum therapeutic daily dosage - 800 mg of the drug.

Overdose. If the maximum allowable therapeutic dose is exceeded and signs of deterioration in the state of health appear, the drug is withdrawn and symptomatic treatment is performed.

Interactions with other drugs. It is not recommended to use Enterofuril in synchronism with sorbents, because the therapeutic effect of the antibiotic will be largely reduced. It is strictly prohibited to drink alcohol during the treatment with Enterofuril. In the body, a disulfiram-like reaction can develop, manifested by vomiting, painful spasms in the epigastric region, tachyarrhythmia, difficulty breathing.

Storage conditions - dry, inaccessible to sunlight, a place with an air temperature of no higher than 30 ° C.

Capsules are suitable for use for 5 years.

[14]

Tablets for poisoning and vomiting

For the treatment of food poisoning, in addition to sorbents and specific antibiotics, agents stimulating the activation of intestinal peristalsis are used. These drugs positively influence the general health of the patient, reduce the frequency of emetic urges and promote the accelerated removal of sorbents with absorbed toxins, reducing the concentration of poisonous compounds. For this purpose, the drug successfully used in tablets Motilium.

Motilium

The drug has a pronounced stimulating effect on peristalsis of the intestine, helps to get rid of attacks of nausea and vomiting. Active active substance - domperidone. Produced in the form of biconvex tablets, protected intestine-soluble shell, lingual tablets and suspension.

Pharmacodynamics. Domperidone is a dopamine hormone antagonist. It blocks the action of dopamine receptors (peripheral and central), increases gastric motility. Has a reducing heartburn, eliminating nausea and antiemetic effects.

Pharmacokinetics. Absorption after oral administration is rapid, especially on an empty stomach. Maximum values in the systemic blood flow the main active substance reaches after 1 hour, by binding to blood plasma proteins (90%). The drug penetrates into various tissues, but almost does not pass the BBB. Metabolized by the liver and in the walls of the intestine. Metabolites are excreted by the intestine and kidneys.

Use of tablets against poisoning in the gestation period and lactation. The use of the drug is permitted if the positive therapeutic effect for the mother exceeds the risk to the fetus and / or the child. The need to use a medicine is decided by a doctor.

Contraindications :

• Presence in the anamnesis or a stage of an exacerbation of an ulcer of any of departments of an intestine;
• Intestinal obstruction;
• Bleeding of the digestive tract;
• Tumors of the pituitary gland;
• Hypersensitivity to the components of the drug;
• Severe pathological lesions of the liver and kidneys;
• Body weight up to 35 kilograms;
• Oral administration of ketakonazole, erythromycin, clarithromycin, nefazodone, antimycotic drugs.

Side effects : impaired motor activity, the appearance of hyperkinesia, which occur when the drug is withdrawn; spastic bowel contractions; enlargement of the mammary glands, amenorrhea, galactorrhea.

Method of administration and dose. Children over 12 years of age and adults are prescribed 20 mg of the drug 3-4 times a day / day before meals. Children under 12 years with a body weight of more than 35 kg - 10 mg 3-4 r. / Day before meals. The maximum daily dosage is 2.4 mg / kg of child weight per day, but not more than 80 mg.

Overdose. There is no specific antidote. Symptoms of drug overdose are: fatigue, lethargy, disorientation in space, impaired motor function. In the treatment of extrapyramidal [disorders, drugs for the therapy of tremor paralysis and anticholinergics can be used. Therapy of an overdose consists in washing the stomach, taking sorbents and symptomatic therapy with the maintenance of vital body functions.

Interactions with other drugs. Reduce the therapeutic activity of Motilium antibiotics of a number of macrolides, antifungal drugs, HIV protease inhibitors, calcium antagonists. It is not recommended simultaneous use with antacids and antisecretory agents. Parallel use of Motilium is possible with neuroleptics and antagonists of dopamine receptors

Storage conditions. The temperature regime is 15-30 ° C. The place is dark, dry, inaccessible to children.

Lingual tablets are stored - 3 years, tablets in a shell - 5 years.

Tablets from nausea in poisoning

Poisoning by food or toxic compounds is often accompanied by phenomena of persistent nausea and excruciating emetic urges. To stop these conditions apply drugs that affect the vomiting center, located in the brain. One of the successfully used medicines for nausea is metoclopramide.

Metoclopramide

The drug has a blocking effect on dopamine and serotonin receptors. It has antiemetic effect, affects the activation of the functions of the digestive tract (strengthens the tone and peristalsis), soothingly affects the hiccup. The active ingredient is metoclopramide.

Pharmacodynamics. Antagonist of dopamine and serotonin receptors. Strengthens the peristalsis of the upper part of the digestive canal and normalizes its motor activity; has a relaxing effect on the sphincter of the duodenum, normalizes the secretion of bile, eliminates dyskinesia of the gallbladder.

Pharmacokinetics. After oral administration, the gastrointestinal tract is absorbed. Within 1-2 hours after intake, reaches the maximum values reaches. It binds to plasma proteins (30%). Passes GEB, penetrates into breast milk. Metabolised by the liver. Eliminated by the kidneys. Can be appointed during gestation.

Contraindications. Hypersensitivity to the drug, internal bleeding, intestinal obstruction, convulsive alertness, tremor paralysis, malignant breast tumors, the first trimester of pregnancy, the age of children under 2 years. Limited use for high blood pressure, bronchial asthma, renal and / or liver failure, old age.

Side effects depend on the dosage and duration of use of the drug: lethargy, drowsiness, weakness, motor disorders (nerve tics facial muscles of the face, opisthotonus, muscle hypertonus, etc.); hypo- or hypertension, tachy- or bradycardia; dry mouth, violations of defecation; urticaria; urinary incontinence, galactorrhea, agranulocytosis, etc.

Basically, the drug is tolerated well by patients. Possible violations of coordination of movement, tremor of hands, lethargy, tinnitus, dry mouth. Prescribe the drug in the pubertal period with caution, because of the emergence of severe side effects from the cardiovascular system.

Method of application and dosage. Typically, adults are prescribed - 1 tab. (10 mg) three times daily before meals. The maximum single dose is 20 mg. Daily - 60 mg. Swallow tablets without chewing and drinking with a sufficient amount of water.

Overdose is characterized by the appearance of characteristic symptoms - confusion, drowsiness, motor disorders. Therapy with an overdose reduces to stopping the drug. Symptoms disappear one day after the last reception.

Interactions with other drugs. Synchronous reception with neuroleptic drugs increases the possibility of developing motor disorders. Simultaneous reception of levodopa decreases the activity of metoclopramide. Parallel use of metoclopramide and drugs that cause CNS depression, the sedation effect is enhanced. Accelerates the absorption of mexiletine, paracetamol, tetracycline. The use of opium-containing drugs and metoclopramide results in blocking the effect on the gastrointestinal motility. Metoclopramide worsens the absorption of cimetidine.

Storage conditions - do not expose to sunlight. Shelf life is 3 years.

Tablets from poisoning and diarrhea

Food poisoning caused by the use of poor-quality food, accompanied by symptoms of nausea, vomiting, fever and diarrhea.

Poisoning caused by rapid growth and release of toxins pathological microflora, require specific therapy. With intestinal infections, treatment is selected depending on the causative agent of the disease. Often, therapy is supplemented with antibiotics or other drugs that have a bacteriostatic effect. All medicines are prescribed by a doctor. Tablets can be used for poisoning and diarrhea, such as levomycetin, tetracycline, furazolidone.

Levomycetin

A broad-spectrum antibiotic used in the treatment of diseases of infectious genesis. Active active ingredient chloramphenicol affects gram-positive and gram-negative bacteria.

Pharmacodynamics. The active substance has a bacteriostatic effect. It stops the growth of bacteria by disrupting the synthesis of proteins inside microorganisms. In high concentrations has a bactericidal effect.

Pharmacokinetics. After oral administration, the gastrointestinal tract is absorbed and easily enters the systemic circulation. Bioavailability - 80%. It binds to plasma proteins (50-60%). It is split by the liver. It is mainly excreted by the kidneys.

Use of tablets against poisoning during pregnancy. The drug easily penetrates the placenta, into breast milk. Pregnant women are not prescribed a drug and are contraindicated during lactation.

Contraindications. Violations of hematopoiesis, acute and chronic liver damage, dermatological diseases (squamous scaly, inflammation of the skin), pregnancy, lactation period, children under 28 days, hypersensitivity to the ingredients of the drug.

Side effects : leukopenia, a decrease in the level of platelets and / or leukocytes, aplastic anemia; nausea, vomiting, diarrhea, excessive accumulation of gases in the intestine; neuritis, cephalalgia, depressive conditions, hallucinations; rash, urticaria, angioedema.

Method and dosage of tablets against poisoning. Adult patients - 500 mg 3-4 r / day. Maximum single-use dosages for children under 3 years of age are prescribed at a rate of 15 mg / kg; for children 3-8 years - 150-200 mg; older than 8 years - 200-400 mg. Reception 3-4 r / day. Therapy usually lasts 1-1.5 weeks.

Interactions with other drugs. When using levomitsetina with butamid, chlorpropamide, their hypoglycemic effects may be intensified. This is due to the oppression of their metabolism, increasing concentrations of drugs in the blood. In such cases, correction of the dose of hypoglycemic drugs is necessary. Levomycetin in combination with drugs that oppress hemopoiesis in the bone marrow, enhances their effect.

The combined use of penicillin, erythromycin, lincomycin and Levomycetin weakens bacteriostatic and bactericidal effects. It is necessary to avoid simultaneous use of several antibiotics.

Increases the accumulation in the blood plasma of phenobarbital, phenytoin, warfarin, slowing down their clearance.

Storage conditions are standard - a dry dark place with an air temperature of 30 ° C. Term of use is 5 years.

Tetracycline

Antibiotic of a tetracycline series of a wide spectrum of action. Produced in tablets, covered with a cachet.

Pharmacodynamics. Tetracycline acts on gram-positive and gram-negative microorganisms. In the cells of bacteria suppresses the synthesis of proteins.

Pharmacokinetics. After oral administration, it is rapidly absorbed into the systemic circulation (66%). It enters the organs and tissues of the body. The exception is the BBB. Cumulates in bone tissue, liver, tissues of tumors. Eliminated with feces and urine.

Use of tablets against poisoning during pregnancy. One of the contraindications to the use of tetracycline are the periods of pregnancy or lactation.

Contraindications. Hypersensitivity to the drug, mycoses of different localization, violations of kidney liver, periods associated with pregnancy and lactation, children under 8 years of age.

Side effects. The drug has good tolerability. Possible dyspeptic manifestations, toxic effects on the kidneys and liver, inflammation of the pancreatic gland, vertigo, the appearance of pigment spots on the skin, intestinal dysbiosis, allergic reactions.

Method of administration and dose. It is applied orally. Adult patients take 250-500 mg as standard for a four-fold application. Children older than 8 years of age, a single dose is calculated depending on body weight at 6.25-12.25 mg / kg. The time interval between taking the tablets is 6 hours. Perhaps twice the use (every 12 hours) and a single dose is calculated at 12.5-25 mg / kg. The usual course of therapy is 5-7 days.

Interactions with other drugs. Do not use medicines containing metal ions together. The effectiveness of tetracycline decreases with synchronous use with derivatives of barbituric acid, carbamazepine. It is not prescribed with antibiotics of the penicillin series. Tetracycline increases the concentration of lithium, digoxin in the blood plasma, enhances the effect of anticoagulants. It is not recommended to take Tetracycline tablets with milk, since disturbed absorption of antibiotic.

Storage conditions. Refers to the preparations of List B. For storage, a dark, dry place with an air temperature of not more than 25 ° C is required. Shelf life - 36 months.

Furazolidone

Antibiotic of broad spectrum of action of the nitrofuran group. It has bacteriostatic and bactericidal action against gram-negative microorganisms (Escherichia, Shigella, Salmonella, Proteus). Gram-positive bacteria (streptococci, staphylococci) are less susceptible to furazolidone.

Pharmacodynamics. Antibacterial and antiprotozoal medicinal product. As the dosage is increased, the bactericidal activity of the preparation is significantly increased. Resistance of pathogens to Furazolidon develops slowly. The drug activates phagocytosis and does not have a depressant effect on the immune system.

Pharmacokinetics. At oral reception Furazolidonum quickly absorbs GASTROINTESTINAL TRACT, gets to a blood channel. Disintegrates in the liver, is able to concentrate in the lumen of the intestine, causing the death of causative agents of intestinal infections. In tissues, the antibiotic does not tend to accumulate. Overcomes the BBB and placental barrier, penetrates into breast milk. Eliminated from the body by the kidneys with urine, giving it a brownish hue. In violation of excretory functions of the kidneys, the clearance of Furazolidon slows down, creating a slight cumulation of the drug in the blood due to delayed excretion.

Contraindications :

• Severe degree of chronic renal failure;
• Functional destructive lesions of the liver;
• Pregnancy and lactation periods;
• Child age up to 1 year;
• Hypersensitivity to the ingredients of the drug and nitrofurans.

Side effects: attacks of nausea, vomiting, loss of appetite; urticaria, itching; phenomena of hemolysis (eosinophilia, agranulocytosis).

Method of administration and dose. Adult patients are prescribed 0.1-0.15 g of furazolidone after a meal of 4 r. / Day. The course of treatment is 5-10 days. Children daily dose is calculated, based on the weight of the child - 10 mg / kg, distributed on a 3-4-fold reception. The drug is not prescribed for more than 10 days. The maximum single dose for adults is 0.2 g, the daily dose is 0.8 g.

Overdosage is manifested by the following symptoms: the emergence of acute toxic hepatitis, the phenomenon of hematotoxicity, polyneuritis. Therapy is reduced to drug withdrawal, gastric lavage, abundant drinking, symptomatic treatment.

Interactions with other drugs. Slows the action of MAO. The efficacy of furazolidone is increased by aminoglycosides and tetracyclines.

Conditions and periods of storage. In a dry, dark place with a temperature of 5 to 30 ° C. Keep away from children. If the storage conditions are met, the expiration date is 36 months. Do not use the drug after the expiration date.

Use of the tablets against poisoning during pregnancy

The organism of a pregnant woman is very sensitive and susceptible to any negative effects of toxic compounds. Minimal quantities of harmful substances can cause serious consequences. The use of alcohol and nicotine during pregnancy lead to severe damage to the brain of the fetus and a delay in the full development of the child after birth. Negative effects on the fetus may include paints and varnishes for hair, decorative cosmetics, creams for face and body skin care. An important role in the full-fledged nurturing of a child is given to the working conditions of a pregnant woman. If a pregnant woman is exposed to toxic substances daily in the workplace, it is worthwhile to think about changing jobs.

Increased attention during gestation requires food. They should be fresh and contain a full amount of fiber, minerals and vitamins. It is necessary to monitor the expiration dates of foods that are part of the diet of a pregnant woman. A small number of pathogenic bacteria and viruses that have entered the body of a woman during the period of bearing a child can cause serious food poisoning. Many toxins of intestinal pathogens easily overcome the placental barrier and have an extremely negative effect on the fetus. If the quality of food provokes the slightest doubt, then it is worth not to use them for food and not jeopardize the health of the unborn child.

Treatment of foodborne toxic infections in pregnant women is complicated by the fact that many of the drugs used, getting into the systemic bloodstream, penetrate the placenta and adversely affect the fetus. If there is a suspicion of an intestinal infection, a specialist consultation is necessary. To avoid the process of generalization of the infection in the body, you should seek help at the initial stages of the disease. To prevent food poisoning, it is necessary to refrain from food of questionable quality.

There are a large number of pills that ease the symptoms of poisoning. Sorbents reduce the toxic effect of poisonous compounds, agents that activate bowel motility, promote the rapid evacuation of absorbed toxins, drugs that affect the centers in the brain, relieve the painful vomiting, antibacterial agents destroy the causative agents of acute intestinal infections. Thanks to modern pharmacology, you can cope with the toxic damage of any genesis.

The presence of a wide range of tablets from poisoning does not entitle you to neglect the rules of personal hygiene and preventive measures to prevent the causative agent from entering the body.