Venoruton 300

Venoruton 300 has angioprotective properties.

Indications of the venoruton 300

The gel is used for such violations:

• edema, along with pain, resulting from injuries;
• pain caused by sclerosing procedures;
• combined elimination of venous insufficiency, which is chronic, varicosity, and in addition symptoms such as a high fatigue, heaviness, and at the same time pain and swelling in the legs.

The purpose of capsules or tablets occurs in such situations:

• venous insufficiency, which is chronic;
• chronic thrombophlebitis;
• ulcers or dermatitis of varicose nature, as well as other disease states that develop due to disorders of microcirculation and trophic processes;
• combined treatment in people who have undergone the process of eliminating varicose veins or the procedure of sclerosing therapy;
• hemorrhoids, against which there are marked signs (itching, pain, rectal bleeding, etc.).

[1]

Release form

The release is carried out in the form of a gel, and with it tablets and capsules.

The externally applied 2% gel is contained in tubes of 40 or 100 g.

Capsules are packed in blister packs in the amount of 10 pieces. The pack contains 2 or 5 blister plates.

Tablets with a volume of 0.5 g contain 10 pieces inside a blister pack, 3 blisters inside the box. Tablets with a volume of 1 g are contained in an amount of 15 pieces inside the blister. In the box - 1 blister plate.

[2], [3], [4], [5]

Pharmacodynamics

The drug has a phlebotensive and angioprotective effect. In addition, it contributes to the correction of disorders of microcirculation processes that affect the change in the membranes of capillaries and vessels. Medication tonic affects the walls of blood vessels, and in addition it strengthens the strength of capillaries. By substantially reducing the pore volume inside the walls of the vessels, Venoruton helps to stabilize their permeability for the passage of lipids along with liquids.

Therapy with the help of Venoruton leads to the restoration of the healthy structure of the vascular endothelium, as well as its functional activity. By suppressing activation mechanisms of action, and besides neutrophilic adhesion, the drug has an anti-inflammatory effect. Together with this, the rutosides contained in it inhibit the activity and release of the mediators of the inflammatory processes.

In addition, the drug has antioxidant properties, due to the action of individual mechanisms. Rutozides weaken the oxidative activity of oxygen, suppress the peroxidative oxidation process against lipids, and also protect vascular tissue, preventing the possibility of development of hypochlorous acid activity together with free radicals.

The medicament allows to improve the rheological parameters of the blood, due to which the erythrocyte aggregation decreases and the degree of their deformation stabilizes. This factor is extremely important in the elimination of venous insufficiency, which is of a chronic nature, as well as deep venous thrombosis. Thanks anticonvulsant, anti-edema and analgesic effects, stabilization of microcirculation occurs, which relieves patients from the appearance of varicose forms of ulcers and trophic disorders in the chronic stage of venous insufficiency.

The medicine helps to improve the overall health of people who suffer from inflammation in the hemorrhoidal veins, as well as weakening itching with bleeding, and in addition to pain in hemorrhoids. Influencing the membranes of the capillaries, as well as the rheological characteristics of the blood, Venoruton interferes with the development of microthrombi and reduces the likelihood of a variety of deviations in vascular origin.

Drinking drugs inside improves the health of people with diabetes, as it inhibits the occurrence of diabetic retinopathy.

[6]

Pharmacokinetics

With external gel treatment, the active component penetrates through the epidermis. Next, the medicine penetrates the subcutaneous layer and the dermis, but it can not be detected inside the blood. Achieving peak indices within the dermis is noted after a lapse of 0.5-1 hour after application; Within the subcutaneous layer, the substance is detected after 2-3 hours.

Penetrating into the body, the drug is poorly absorbed from the digestive tract - this figure is about 10-15%. Peak indices inside the blood plasma are noted after 4-5 hours even in case of using a single dose of medication.

The half-life of the active element is about 10-25 hours. Metabolic processes lead to the production of glucuronized components.

Excretion of the drug is carried out with feces, bile, and urine - is derived as an unchanged element, and the products of its metabolism.

[7]

Dosing and administration

Use of tablets with capsules.

You can take the drug solely with the appointment of the treating doctor, taking into account the severity of the pathology, and also the individual characteristics of the patient.

When eliminating the chronic stage of venous insufficiency, and in addition to hemorrhoids or varicose veins, it is necessary to prescribe an adult drug intake in the initial portion of 0.3 g (three times a day) or 0.5 g (twice a day). There is also a variant with taking drugs in a dose of 1 g, once a day.

Tablets or capsules must be consumed with food. Therapy is carried out until the complete disappearance of all signs of the disease. After the next appearance of the symptoms of the pathology, it is allowed to repeat the treatment course. On average, the result of therapy lasts for 1 month. If there are negative symptoms, you can use the medicine in supporting daily portions - 0.6 g / day.

Use of gel.

The gel is applied externally, maximum twice a day. It is necessary to treat the skin with a thin layer of medicine, then rub it until it is completely absorbed. In addition, the drug can be applied to special stockings or elastic bandage.

After complete disappearance of the signs of the disease, it is necessary to apply the substance in a supportive regime - to treat the skin several times a day (it is recommended to carry out this procedure overnight).

[9], [10], [11], [12]

Use of the venoruton 300 during pregnancy

It is forbidden to appoint Venoruton on the 1st trimester of pregnancy.

Contraindications

Contraindication is the intolerance of the elements of the drug.

Side effects of the venoruton 300

The drug is usually well tolerated, although occasionally some side effects develop - for example, vomiting, heartburn, abdominal pain, stool disorders and nausea. Occasionally there are headaches or hyperemia affecting the upper body region.

With external gel treatment, at times, allergies occur - for example, hives or itching.

[8]

Interactions with other drugs

Potentiation of the properties of Venoruton occurs when it is combined with medicaments that contain vitamin C.

[13], [14]

Storage conditions

Venorutone is required to be kept in a dark and dry place, closed from the access of young children.

[15], [16], [17], [18], [19]

Shelf life

Venorutone is allowed to be used for 4 years after the release of the drug.

[20]

Reviews

Venorutone is a fairly discussed drug. Most of the comments at the same time contain positive feedback on the effectiveness of the drug. Many patients suffering from various forms of lymphovenous insufficiency note that the state of health after using drugs is significantly improved.

Often patients write about the high efficiency of the gel. Often, such reviews are associated with the stabilization of venous disorders in the leg area. In addition, there is evidence of a weakening of signs of exacerbation of hemorrhoids - the effect of the gel made it possible to accelerate this process many times.

Quite often the drug is mentioned by pregnant women - they are often prescribed for elimination of fetoplacental insufficiency, and in addition, in cases of venous outflow (due to the pressure exerted by the fetus on the vessels). In such cases, the use of capsules or other forms of drugs should be stopped a few weeks before the expected date of delivery.

Doctors often advise patients to use Venoruton. It is believed that he perfectly treats venous insufficiency and, in particular, hemorrhoids.

Medication is considered to be one of the most powerful venotonic drugs. But you need to consider that even it needs to be combined with additional factors - such as changing lifestyle with diet, wearing special compression underwear, and also using other drugs and procedures that have a positive effect on veins and lymphatic vessels. Only such an approach will provide the required medicinal effect.