Venoruton 300.

Venoruton 300 has angioprotective properties.

Indications Venoruton 300.

The gel is used for the following disorders:

• swelling along with pain sensations that appeared as a result of injuries;
• pain caused by sclerotherapy procedures;
• combined elimination of venous insufficiency of a chronic nature, varicose veins, as well as such symptoms as a feeling of high fatigue, heaviness, and at the same time pain and swelling in the legs.

Prescription of capsules or tablets occurs in the following situations:

• venous insufficiency of a chronic nature;
• chronic thrombophlebitis;
• ulcers or dermatitis of a varicose nature, as well as other painful conditions that develop due to disorders of microcirculation and trophic processes;
• combination treatment in people who have undergone varicose vein removal or sclerotherapy procedures;
• hemorrhoids, against the background of which pronounced symptoms are observed (itching, pain, rectal bleeding, etc.).

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Release form

It is released in the form of a gel, as well as tablets and capsules.

The 2% gel applied externally is contained in tubes of 40 or 100 g.

The capsules are packaged in blister packs of 10. The pack contains 2 or 5 blister strips.

Tablets of 0.5 g are contained in 10 pieces inside a blister pack, 3 blisters inside a box. Tablets of 1 g are contained in the amount of 15 pieces inside a blister. There is 1 blister plate in a box.

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Pharmacodynamics

The medicine has a pronounced phlebotonic and angioprotective effect. In addition, it helps to correct microcirculation disorders that affect the change in capillary and vascular membranes. The medicine has a tonic effect on the walls of blood vessels, and in addition, it strengthens the strength of capillaries. By significantly reducing the size of pores inside the walls of blood vessels, Venoruton helps to stabilize their permeability for the passage of lipids along with liquids.

Venoruton therapy leads to the restoration of the healthy structure of the vascular endothelium, as well as its functional activity. By suppressing the activation mechanisms of action, as well as neutrophil adhesion, the drug has an anti-inflammatory effect. At the same time, the rutosides contained in it suppress the activity and release of mediators of inflammatory processes.

In addition, the drug has antioxidant properties due to the action of individual mechanisms. Rutosides weaken the oxidative activity of oxygen, suppress the peroxidative process in relation to lipids, and also protect vascular tissues, preventing the possibility of developing hypochlorous acid activity together with free radicals.

The medication improves blood rheological parameters, thereby reducing erythrocyte aggregation and stabilizing their deformation. This factor is extremely important in eliminating chronic venous insufficiency, as well as deep venous thrombosis. Due to the anticonvulsant, anti-edematous and analgesic effects, microcirculation is stabilized, which saves patients from the appearance of varicose ulcers and trophic disorders in the chronic stage of venous insufficiency.

The medicine helps improve the general health of people who suffer from inflammation in the hemorrhoidal veins, as well as relieve itching with bleeding, and also pain in hemorrhoids. By affecting the capillary membranes, as well as the rheological characteristics of the blood, Venoruton prevents the development of microthrombi and reduces the likelihood of various deviations of vascular origin.

Oral use of the drug leads to an improvement in the health of people with diabetes, as it slows down the development of diabetic retinopathy.

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Pharmacokinetics

When applied externally, the active component penetrates the epidermis. The medicine then penetrates the subcutaneous layer and dermis, but it cannot be detected inside the blood. Peak values inside the dermis are reached 0.5-1 hour after application; inside the subcutaneous layer, the substance is detected after 2-3 hours.

When penetrating the body, the medicine is weakly absorbed from the gastrointestinal tract - this figure is about 10-15%. Peak indicators in the blood plasma are noted after 4-5 hours, even in the case of taking a single dose of the medicine.

The half-life of the active element is approximately 10-25 hours. Metabolic processes lead to the production of glucuronidated components.

The excretion of the drug occurs with feces, bile, and urine - both the unchanged element and the products of its metabolism are excreted.

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Dosing and administration

Use of tablets with capsules.

The drug can be taken only as prescribed by the attending physician, taking into account the severity of the pathology, as well as the individual characteristics of the patient.

When eliminating the chronic stage of venous insufficiency, as well as hemorrhoids or varicose veins, adults must be prescribed the drug in an initial dose of 0.3 g (three times a day) or 0.5 g (twice a day). There is also an option with taking the drug in a dose of 1 g, once a day.

Tablets or capsules must be taken with food. Therapy is carried out until all signs of the disease disappear completely. After the next appearance of symptoms of the pathology, it is allowed to repeat the treatment course. On average, the result of therapy lasts for 1 month. If negative symptoms occur, it is allowed to take the medicine in maintenance daily portions - 0.6 g / day.

Using the gel.

The gel is applied externally, maximum twice a day. It is necessary to treat the skin with a thin layer of the medicine, then rub it in until it is completely absorbed. In addition, the drug can be applied under special stockings or an elastic bandage.

After the signs of the disease have completely disappeared, the substance should be applied in a maintenance mode - treat the skin with it several times a day (it is recommended to carry out this procedure at night).

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Use Venoruton 300. during pregnancy

It is prohibited to prescribe Venoruton during the 1st trimester of pregnancy.

Contraindications

Contraindication is intolerance to the components of the drug.

Side effects Venoruton 300.

The drug is usually well tolerated, although sometimes individual side effects develop - for example, vomiting, heartburn, abdominal pain, bowel disorders and nausea. Headaches or hyperemia affecting the upper body occasionally appear.

When applied externally with the gel, allergic reactions sometimes occur, such as hives or itching.

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Interactions with other drugs

The properties of Venoruton are enhanced when combined with medications that contain vitamin C.

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Storage conditions

Venoruton should be kept in a dark, dry place, out of the reach of small children.

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Shelf life

Venoruton can be used for 4 years from the date of release of the drug.

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Reviews

Venoruton is a fairly discussed drug. Most comments contain positive feedback on the effectiveness of the drug. Many patients suffering from various forms of lymphovenous insufficiency note that their well-being improves significantly after using the drug.

Patients often write about the high efficiency of the gel. Often, such reviews are associated with the stabilization of venous disorders in the legs. In addition, there is data on the weakening of the signs of exacerbation of hemorrhoids - the effect of the gel made it possible to accelerate this process many times.

The drug is often mentioned by pregnant women – it is often prescribed to them to eliminate fetoplacental insufficiency, and in addition to this, for venous outflow disorders (due to pressure exerted by the fetus on the vessels). In such cases, the use of capsules or other forms of drugs should be discontinued several weeks before the expected date of birth.

Doctors often advise patients to use Venoruton. It is believed that it is an excellent treatment for venous insufficiency and, in particular, hemorrhoids.

The drug is considered one of the most powerful venotonics. But it should be taken into account that even it needs to be combined with additional factors - such as lifestyle changes with diet, wearing special compression underwear, and also the use of other drugs and procedures that have a positive effect on veins and lymphatic vessels. Only such an approach will provide the required medicinal effect.