Medical expert of the article
New publications
Preparations
Rinse throat with furcilin in angina
Last reviewed: 23.04.2024
All iLive content is medically reviewed or fact checked to ensure as much factual accuracy as possible.
We have strict sourcing guidelines and only link to reputable media sites, academic research institutions and, whenever possible, medically peer reviewed studies. Note that the numbers in parentheses ([1], [2], etc.) are clickable links to these studies.
If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please select it and press Ctrl + Enter.
Does Furacilin help with sore throat? It helps if the development of acute tonsillitis is caused by strains of strepto- and staphylococci, sensitive to this antiseptic group of nitrofurans.
Its local antimicrobial effect extends to staphylococcal and streptococcal infection, as well as to intestinal bacteria (Escherichia, Shigella and Salmonella). But, as is known, the most common cause of this disease is adeno- and coronaviruses, a respiratory syncytial virus, etc.
Therefore, use furatsilin with purulent angina associated with the bacterial defeat of the tonsils (most often pyogenic streptococcus), it is possible - as an auxiliary.
But Furatsilin with herpes simplex caused by the herpes simplex virus, is unlikely to benefit, because the antiseptic properties of nitrofurans do not affect the viruses.
Indications Furacilin with angina
In domestic medicine, indications for the use of Furacilin solution (other trade names - Nitrofural, Nitrofurazon) include the treatment of infected wounds and burns, washing of various cavities during surgical interventions, sanitation of the bladder and urethra after catheterization.
Dentists recommend mouthwash with inflammation of the mucous membrane or gums; in ophthalmology this agent is used to treat the conjunctiva and the edges of the eyelids in cases of their inflammation. In otorhinolaryngology, Furacilin can be used for inflammation of the auditory canal and purulent otitis, for washing the paranasal sinuses with sinusitis and frontalitis. A solution of furatsilina with angina is used to rinse the throat.
Specific information about whether it is possible to use it for children is not available (obviously experience with the use of furatsilina in pediatric practice has not been studied), but gargle with Thuracilin throat for children from four to five years old (when they are able to perform this procedure).
It should be noted that in the US and many countries of Western Europe, this antiseptic was included in the group of obsolete funds. Furacilin was synthesized in the mid-40's. Of the last century by the Latvian organic chemist SA Giller (1915-1975).
Why is Furacilin obsolete? Because there are more effective and safe antimicrobials. Animal studies conducted in the United States in the 1980s (within the framework of the National Toxicology Program) demonstrated evidence of embryotoxic (teratogenic) and even carcinogenic effects of Nitrofurazone, after which its use for humans was discontinued.
Everywhere, nirofurans are used in poultry and fish farming. In Canada, a sterile solution of Furacilin is a veterinary drug for the treatment of superficial bacterial infections, pyoderma, eczema and osteomyelitis in horses, but the Federal Law prohibits this product from being used by animals whose meat is intended for human consumption. This is due to the fact that in people with congenital deficiency of glucose-6-phosphate dehydrogenase, nitrofurans in consumed meat or fish are able to affect red blood cells with the development of hemolytic anemia.
Abroad, any means for internal use containing derivatives of nitrofurans are forbidden for pregnant women. It is allowed to use during the pregnancy solution of furacilin for gargling, but doctors warn: pregnant women can not swallow this solution.
Release form
Furacilin is released in the form of tablets (20 mg each) - for the preparation of an aqueous solution; finished aqueous solution (0.02%) - for external use; alcohol solution (0.066%).
Also in pharmacies there is furatsilinovaya ointment (0.2%), used in surgery and ophthalmology.
[6],
Pharmacodynamics
The mechanism of pharmacological action of furacilin, which is a synthetic derivative of heterocyclic polychlorobenzofuran compounds of the furans class (5-nitrofurfurol), consists in the irreversible transformation of proteins of microorganisms, including their RNA.
The modification occurs due to the presence of an electron-withdrawing group that absorbs molecular oxygen in the mitochondria of protein dehydrogenase enzymes of bacteria, which leads to a disruption of their cellular respiration and general metabolism.
As a result, either the slowdown in the synthesis of nucleic acids in bacterial cells (this is a bacteriostatic effect) or, at a higher concentration of furacilin, bactericidal action is noted, that is, microbes are killed.
[7]
Dosing and administration
Furacilin with angina is applied topically, the maximum single dose is 0.1 g; daily - 0.5 g.
The instructions indicate how to dilute furacilin with angina, using tablets that are dissolved in hot water, pre-grinding them to a powdery state.
Rinse with furatsilinom angina, the proportion: per 100 ml of water - one tablet, the solution should be a little warm.
How many times and how often to gargle Thuracilinum with angina is also indicated in the instruction: the throat should be rinsed five to six times during the day, the duration of each rinse is about three minutes.
Read also - Rinse the throat with furacilin for children and adults, during pregnancy: instructions on how to cook
[11]
Contraindications
Furacilin, like other nitrofurans, is contraindicated for individual hypersensitivity to drugs of this group, in the presence of allergic dermatoses, with kidney failure, as well as in case of hemolytic anemia.
Preparations of the group of nitrofurans for internal use are prohibited for pregnant women (in the last trimester) and children up to a year.
[8],
Storage conditions
Given the increased photosensitivity of nitrofurans, the optimal storage conditions for Furacilin: a dark, protected from moisture place, a temperature of <+ 25 ° C.
[12]
Shelf life
The shelf life of Furacilin tablets is 5 years, the solution is 12 months.
Analogues
Analogues furatsilina for gargles of a throat at an acute tonsillitis are Hexetidine (Geksoral), Angileks (Givaleks, Hepilor), Dekasan (0.02% r decametoxin solution). More useful information in the material - Effective means for gargling with angina;
Instead of furatsilina for inhalation Miramistin (0.01% solution) or Rivanol (0.2% solution) is used. Relieve inflammation and reduce the pain of aerosol: Kampomene (with menthol, eucalyptus oil and furatsilinom); Stopangin (with hexetidine and essential oils), Oracept (with phenol), etc. See also - Aerosols from sore throats
Attention!
To simplify the perception of information, this instruction for use of the drug "Rinse throat with furcilin in angina" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.