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Magne-B6 premium
Last reviewed: 03.07.2025

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Modern technogenic society has made human life emotionally uncomfortable. One of the reasons predisposing a person to stress is the lack of such an element as magnesium in his body. This chemical element is actively involved in many physiological and biochemical processes occurring in the body, so its deficiency significantly affects the general health of a person. In such a situation, Magne-B6 premium will come to the rescue - a highly effective medical product that can solve the problem of magnesium deficiency in the patient's body. But it is worth noting that food should not be discounted. A balanced diet rich in magnesium-containing foods can also at least partially relieve the problem of a lack of this element.
Indications Magne-B6 premium
The pharmacological characteristics of magnesium citrate and pyridoxine “dictate” the indications for the use of Magne-B6 premium.
- Replenishment of magnesium deficiency in the human body, both isolated and in combination.
- Primary, or congenital, metabolic anomaly (chronic hypomagnesemia).
- Magne-B6 premium is approved for use by both adult patients and children, even young ones (their weight should be at least 10 kg, which is approximately equivalent to one year of age).
- Magnesium deficiency in the body can be caused by:
- A severe form of anemia associated with malnutrition.
- Smoking, addiction to alcoholic beverages, drug addiction.
- Chronic diarrhea.
- Abuse of diuretics.
- Hypoparathyroidism is an endocrinopathy associated with insufficient synthesis of the parathyroid hormone – parathyroid hormone.
- Fistulas in the gastrointestinal tract.
- Severe form of polyuria.
- Chronic pyelonephritis.
- Primary hyperaldosteronism is a condition of the body, due to improper functioning of the endocrine system, in which the adrenal cortex begins to produce an excess amount of the enzyme aldosterone.
Symptoms that indicate a deficiency of this element:
- There is a feeling of goosebumps and microcurrents running through the muscles of the body.
- Convulsive symptoms.
- Increased nervousness, feeling of anxiety.
- Rapid fatigue.
- Irritability.
- Psycho-emotional lability.
- Mild insomnia.
- Minor spasms in the gastrointestinal system.
- Attacks of minor tachycardia ( rapid heartbeat ).
- Paresthesia is a sensory disorder.
Release form
For adult patients and children over six years of age, the recommended dosage form is tablets, which contain anhydrous magnesium citrate in the amount of 618.43 mg (this volume corresponds to 100 mg of mono magnesium) and 10 mg of pyridoxine hydrochloride. The unit of the drug is white and oval. Additional chemical compounds include macrogol 6000, anhydrous lactose, lactate and magnesium stearate. The tablet is coated with a shell consisting of titanium dioxide, hypromellose, macrogol 6000 and talc.
On the shelves of modern pharmacies you can also find Magne-B6 for injections, released in the form of 10 ml ampoules (No. 10).
Pharmacodynamics
Physiologically, ionized magnesium is classified as a cation – a positively charged ion that is located inside the cell. The chemical element magnesium effectively suppresses the overexcitability of neurons, the increased reaction of which leads to emotional instability in humans. Magnesium reduces neuromuscular reactions that provoke loss of sensitivity and muscle spasms. It also participates in most enzymatic processes occurring in the body.
Pharmacodynamics Magne-B6 Premium also affects metabolic processes, here pyridoxine (coenzyme factor) realizes itself. The highest percentage of the chemical compound Magne-B6 Premium is observed in bone tissues.
The presence or absence of a magnesium deficiency is determined by the concentration of magnesium in the blood:
- If the quantitative content of the element shows a figure that falls within the range of 12 mg to 17 mg per liter of blood serum (which corresponds to 500 - 700 mol per liter or 1.0 - 1.4 mEq per liter), then the doctor diagnoses a moderate level of magnesium deficiency in the plasma.
- An indicator of 17 mg per liter and above (which corresponds to 700 mol per liter or 1.4 mEq per liter) indicates a sufficient amount of the chemical element for the normal functioning of the human body.
- If the quantitative magnesium content indicator shows a figure less than 12 mg per liter of the test medium (which corresponds to 0.5 mmol per liter or 1.0 mEq per liter), this indicator indicates a severe form of magnesium deficiency.
Pharmacokinetics
Up to half of the magnesium salts entering the human body are absorbed by the gastrointestinal mucosa by simple mechanical absorption. The main role in this process is played by the ability of salts to dissolve. The utilization and excretion of the drug is mainly carried out through the renal tract together with urine, while magnesium salts in the renal canals undergo additional reabsorption - this is the pharmacokinetics of Magne-B6 premium. The average amount of magnesium excreted in urine is a third of the amount of this element that entered the body with food.
A third of the magnesium found in compounds accumulates in the blood plasma, as well as in striated and smooth muscles, but still the majority “settles” in the intracellular space of bone tissue.
Dosing and administration
If the medicine is prescribed in tablet form, it is recommended to swallow it whole, without crushing, together with food. It is better to wash it down with water in sufficient quantity. The method of administration and dosages vary slightly for different age categories of patients.
The starting dosage of Magne-B6 Premium for adult patients is three to four tablets, administered in two to three doses. In case of medical necessity, the quantitative component can be doubled, bringing the daily dose to six to eight tablets.
In the form of injections, the daily amount of the drug is three to four ampoules, administered two to three times a day.
For children over six years of age (whose weight is over 20 kg), the amount required for administration of the drug is calculated using the formula: 10 to 30 mg of Magne-B6 Premium taken per kilogram of the small patient's weight per day (approximately 0.4–1.2 mmol per kilogram of the child's body weight per day). This usually corresponds to two to four tablets, diluted two to three times. In the case of severe magnesium deficiency, the daily amount of the drug can be increased to four to six tablets.
After the therapeutic effect has occurred (the magnesium level in the blood has reached the normal level), the drug should be discontinued. The duration of therapy is usually one month. If the therapeutic effect has not occurred after a month of taking the drug, it should still be discontinued and a more thorough examination should be carried out to diagnose the underlying cause of the pathological magnesium deficiency in the body.
For children under one year of age, weighing up to 10 kg, Magne-B6 premium is administered orally in the form of a solution. The starting daily dosage is from one to four ampoules, administered in two to three doses throughout the day. Before giving the medicine to the baby, the ampoule must be opened and its contents diluted with half a glass of water at room temperature.
Use Magne-B6 premium during pregnancy
Long-term monitoring and clinical studies have shown that the use of Magne-B6 Premium during pregnancy is permissible at any stage. It is only worth noting that the drug should be prescribed and monitored by the attending physician or obstetrician-gynecologist who is monitoring the pregnancy. At the same time, all components of the drug, both in combination and separately, do not have any negative impact on breast milk, and it, in turn, on the newborn. Therefore, taking Magne-B6 Premium during lactation is permissible.
Contraindications
No matter how unsafe the drug is, it is still necessary to be more attentive to the prescription, schedule of administration and dosage of any pharmacological drug. There are also contraindications to the use of Magne-B6 Premium, although they are insignificant.
- Individual intolerance to one or more components of the drug.
- If creatinine clearance is below 30 ml per minute and severe renal dysfunction is observed.
- Deficiency of sucrase-isomaltase in the patient's blood.
- Age of children under six years of age (for tablets).
- Hypersensitivity to fructose.
- Co-administration with levodopa (therapeutic therapy used to relieve symptoms of Parkinson's disease).
- Impaired absorption (malabsorption) of glucose or galactose.
Side effects Magne-B6 premium
The use of the drug in question in the treatment protocol can provoke side effects of Magne-B6 premium, which give the following symptoms:
- The appearance of loose stools (diarrhea) with accompanying symptoms.
- Pain in the abdomen (abdominal pain).
- Allergic manifestations reflected on the skin.
- Another manifestation of allergy.
- Bronchial spasm.
Overdose
Predominantly, with increased introduction of Magne-B6 premium into the patient's body, in case of normal kidney function, a toxic reaction is not observed. However, if the patient suffers from renal failure, an overdose of magnesium can give side symptoms. In this case, the body can react to magnesium poisoning:
- A sharp decrease in blood pressure.
- Attacks of nausea, the increased intensity of which can lead to vomiting.
- Depression of nerve endings of the central nervous system.
- Reflex disorders.
- Problems with the functioning of the heart muscle.
- Inhibition of respiratory processes, up to a comatose state, characterized by paralysis of the respiratory system and cardiac arrest.
- Decreased general vitality (anuric syndrome).
If such symptoms appear, urgent rehydration of the patient's body is necessary (inducing a gag reflex, washing the stomach), forced diuresis using strong medications. In case of severe renal failure, hemodialysis or peritoneal dialysis cannot be avoided.
Interactions with other drugs
Even the most harmless but useful vitamin must be taken very carefully in combination therapy, so as not to stop the effect of other drugs or cause another undesirable reaction. Therefore, it is necessary to know the features of the interaction of Magne-B6 premium with other drugs.
The drug in question should not be used together with levodopa, since Magne-B6 premium in this case significantly reduces the activity of levodopa, or even completely blocks it. The way out of this situation is the additional connection of peripheral dopa-decarboxylase.
It is not recommended to administer calcium salts or phosphate compounds together with the drug in question. They can stop magnesium from being absorbed by the mucous membrane of the small intestine.
The need for tandem use of Magne-B6 Premium with tetracyclines should be treated with great caution, as magnesium can reduce the gastric absorption of the latter. To prevent this, it is necessary to administer the drugs orally to the patient at intervals of two hours.
Storage conditions
The basic storage conditions for Magne-B6 Premium are similar to the basic requirements for any pharmacological drug:
- The room temperature should not exceed 30 o C.
- The storage area should not be exposed to direct sunlight.
- The medicinal product Magne-B6 premium should not be available to small children.
Shelf life
Two years is the expiration date of the drug, which must be marked on the packaging box and duplicated on the tablet blasters or solution ampoules. It is strongly recommended not to use the drug after this expiration date.
Attention!
To simplify the perception of information, this instruction for use of the drug "Magne-B6 premium" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.