Fazijin

Fazizhin is a drug used in surgery and for the treatment of infectious diseases. We suggest you learn the most useful information about the drug, how to use it correctly and what precautions to take when using the drug. So, first things first.

Fazizhin contains the active substance tinidazole. Thus, one tablet of the drug contains 500 mg of the active substance tinidazole. The composition of the drug also includes a number of auxiliary substances, such as: corn starch, alginic acid, magnesium stearate, hypromellose, titanium dioxide and others.

Indications Fazijin

The main indications for the use of Fazizhin are various types of anaerobic infections. Such infections include:

• Peritonitis
• Endometritis
• Tuboovarian abscess
• Pneumonia
• Bacterial septicemia
• Non-specific vaginitis
• Giardiasis
• Postoperative wound infections
• Acute ulcerative gingivitis
• Infectious diseases of soft tissues and skin
• Postoperative prevention of gastrointestinal tract and gynecological diseases.

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Release form

The drug is available in film-coated tablets. One tablet contains 500 mg of the active ingredient tanidazole. One package of the drug contains one blister and four tablets of the drug in it.

The drug is available on prescription. To keep the drug safe, it is very important to follow all the rules and conditions for storing the medicine.

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Pharmacodynamics

Pharmacodynamics of Fazizhin shows the properties of the drug, which are included in the substance. The drug is active against obligate and protozoan anaerobic bacteria. The drug works effectively against: Trichomonas vaginalis, Giardia lamblia and Entamoeba histolytica. The main mode of action of the drug is penetration into cells affected by microorganisms and damage to DNA strands or inhibition of their synthesis.

Fasigin is active against the following anaerobic bacteria:

• Gardnerella vaginali
• Bacteroides melaninogenus
• Helicobacter pylori
• Veillonella
• Bacteroides fragilis
• Eubacterium
• Peptostreptococcus
• Peptococcus
• Bacteroides
• Helicobacter pylori
• Fusobacterium

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Pharmacokinetics

Pharmacokinetics of Fazizhin allows you to learn about the process of metabolism, absorption and excretion of the drug. After taking the drug, the active substances are quickly absorbed. Complete dissolution of the drug in the body occurs two hours after taking. About 12% of the substance binds to proteins, the remaining part of the drug is excreted by the kidneys and liver.

If the drug is prescribed to women who are breastfeeding, then it is worth giving up lactation. Since the drug is excreted through breast milk and can enter the baby's body. If the drug is prescribed to people with renal failure, then the drug does not change its pharmacokinetic properties.

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Dosing and administration

The method of administration and dosage of the drug are determined by the attending physician and depend on what disease the drug should eliminate. In any case, the drug should be taken orally before or during meals. Children under 12 years of age are not recommended to use the drug, as uncontrolled and unpredictable reactions of the body are possible. Let's consider the dosage of the drug Fazizhin for various diseases.

• Preventive measures against postoperative infections – 2 g of the drug 12-14 hours before surgery.
• Anaerobic infections – the first dose of the drug is 2 g, the following 1 g once a day or 500 mg twice a day. The duration of treatment does not exceed 5 days.
• Ulcerative gingivitis – 2 g once a day.
• Urogenital trichomoniasis – 2 g once a day.
• Non-specific vaginitis – 2 g of the drug for two days.
• Intestinal amebiasis – 2 g of the drug once a day for three days.
• Liver damage (amoebic) - 1.5 g once a day for three days. In this disease, the drug Fazizhin can be used as an auxiliary drug. In this case, the dose of the drug is adjusted by the doctor.

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Use Fazijin during pregnancy

The use of Ubistezin during pregnancy is not recommended. However, when studying the drug, no deviations were found that would have an adverse effect on the body of a pregnant woman and the development of the body of the future baby. Ubistezin during pregnancy can be used only in extreme cases, when the benefit to the mother is more important than the potential risk to the fetus.

When taking the drug during lactation, you should refrain from breastfeeding. Since the remains of the drug are excreted from the body with the help of milk. Many doctors recommend expressing the first portion of milk, since it is in it that a high percentage of the drug is concentrated. You should also refrain from working with mechanical devices and driving a car.

Contraindications

The main contraindications to the use of Fazizhin are individual intolerance to the components of the drug. During treatment, it is necessary to refrain from drinking alcohol. Women who are in the process of lactation should stop breastfeeding and start it five years after the end of taking the drug.

If neurological symptoms are observed in patients during the drug administration, the drug should be discontinued. For a course of treatment exceeding seven days, laboratory and clinical parameters must be monitored.

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Side effects Fazijin

All side effects of Fazizhin are based on the body's reactions to the active substance in the drug. Let's look at the main side effects of the drug Fazizhin.

• Dizziness
• Cramps
• Ataxia
• Nausea
• Peripheral neuropathy
• Vomit
• Diarrhea and abdominal pain
• Headache
• Metallic taste in the mouth
• Skin rashes
• Allergic reactions
• Angioedema

If any of the above side effects occur, you should stop using the drug and seek medical attention.

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Overdose

An overdose of the drug Fazizhin may occur due to an incorrectly prescribed dose of the drug. The main symptoms of an overdose are:

• Dizziness
• Nausea and vomiting
• Severe headache
• Allergic reactions on the skin
• Fever and chills

The most proven treatment for drug overdose is gastric lavage and temporary discontinuation of drug use.

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Interactions with other drugs

Incompatibility of interaction of Fazizhin with other drugs has not been recorded. But the drug is not recommended to be used simultaneously with a number of other drugs of similar action, as this puts increased pressure on the body.

The drug is incompatible with alcohol, since alcohol consumption can cause the development of an alcohol-antabuse-like reaction, abdominal pain, vomiting and tachycardia. When prescribing treatment with Fazizhin, the doctor checks the drugs for compatibility and only then prescribes a course of drugs that include Fazizhin.

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Storage conditions

The storage conditions of Fazizhin correspond to the rules for storing all medicinal products. The tablets must be stored out of the reach of children, while maintaining a temperature of no more than 25 ° C. The drug must also be kept away from direct sunlight. If the storage rules for the drug are not followed, Fazizhin must be disposed of.

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Shelf life

The shelf life of the medicinal product Fazizhin is two years from the date of manufacture indicated on the packaging of the tablets. After the expiration date, the unused product must be thrown away, as it has lost its medicinal functions. It is strictly forbidden to take the product after the expiration date, as this will cause a number of unpredictable reactions of the body.

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