Fazijin

Fazijin is a medicinal product used in surgery and for the treatment of infectious diseases. We suggest you to find out the most useful information about the preparation, how to use it correctly and what precautions to take when applying the drug. So, about everything in order.

Fazijin contains in its composition an active substance - tinidazole. So one tablet of the drug contains 500 mg of the active ingredient tinidazole. The composition of the drug includes a number of auxiliary substances, such as: corn starch, alginine acid, magnesium stearate, hypromellose, titanium dioxide and others.

Indications Fazijin

The main indications for the use of Fazijin are various kinds of anaerobic infections. Such infections include:

• Peritonitis
• Endometritis
• Tubourovarial abscess
• Pneumonia
• Bacterial septicemia
• Nonspecific vaginitis
• Lambliasis
• Postoperative wound infections
• Acute Ulcerative Gingivitis
• Infectious diseases of soft tissues and skin
• Postoperative prophylaxis of the gastrointestinal tract and gynecological diseases.

[1], [2], [3], [4], [5], [6], [7]

Release form

The form of the drug is coated tablets. One tablet contains 500 mg of the active ingredient tanidazole. One package contains one blister and four tablets.

The drug is issued by prescription. For the safety of the drug is very important to comply with all rules and conditions for storage of the drug.

[8], [9], [10], [11]

Pharmacodynamics

Pharmacodynamics Fazizhin shows the properties of the drug, which are part of the substance. The drug is active against obligate and protozoa anaerobic bacteria. The drug works effectively against: Trichomonas vaginalis, Giardia lamblia and Entamoeba histolytica. The main method of the drug is penetration into cells affected by microorganisms and damage to DNA strands or inhibition of their synthesis.

Fazizhin is active against such anaerobic bacteria:

• Gardnerella vaginali
• Bacteroides melaninogenicus
• Helicobacter pylori
• Veillonella
• Bacteroides fragilis
• Eubacterium
• Peptostreptococcus
• Peptococcus
• Bacteroides
• Helicobacter pylori
• Fusobacterium

[12], [13], [14], [15]

Pharmacokinetics

Pharmacokinetics Fazizhin allows you to learn about the process of metabolism, absorption and excretion of the drug. After taking the drug, the active substances are rapidly absorbed. Complete dissolution of the drug in the body occurs two hours after ingestion. About 12% of the substance binds to proteins, the rest of the drug is excreted by the kidneys and liver.

If the drug is prescribed to women who are breastfeeding, then it is worth noting lactation. Since the drug is excreted through breast milk and can enter the baby's body. If the drug is prescribed to people with renal insufficiency, then the drug does not change its pharmacokinetic properties.

[16], [17], [18], [19], [20], [21],

Dosing and administration

The way of application and the dose of the drug are determined by the attending physician and depend on which disease the drug should eliminate. In any case, the drug must be taken orally before or during meals. Children who are under 12 years of age are not recommended to use the drug, since uncontrolled and unpredictable reactions of the body are possible. Let's consider the doses of the drug Fazijin for various diseases.

• Preventive measures of postoperative infections - 2 g of the drug 12-14 hours before the operation.
• Anaerobic infections - the first dose of the drug - 2 g, followed by 1 g once a day or 500 mg twice a day. The duration of treatment does not exceed 5 days.
• Ulcerative gingivitis - 2 g once a day.
• Urogenital trichomoniasis - 2 g once a day.
• Nonspecific vaginitis - 2 g of the drug for two days.
• Intestinal amebiasis - 2 g of the drug once a day for three days.
• Lesions of the liver (amoebic) - 1,5 g once a day for three days. With this disease, Fazijin can be used as an auxiliary drug. In this case, the dose of the drug is regulated by a doctor.

[28], [29], [30], [31]

Use Fazijin during pregnancy

Use of Ubestezin during pregnancy is not recommended. But in the study of the drug, there were no abnormalities that would adversely affect the pregnant woman's body and the development of the future baby's body. Ubistezin during pregnancy can be used only when absolutely necessary, when the benefit to the mother is more important than the potential risk to the fetus.

When taking the drug during lactation it is necessary to refuse breastfeeding. Since the remnants of the drug are excreted from the body with the help of milk. Many doctors recommend that you express the first portion of milk, since it is in it that a high percentage of the drug is concentrated. It is also worth not to work with mechanical devices and driving a car.

Contraindications

The main contraindications to the use of Fazijin are individual intolerance of the drug components. During treatment it is necessary to refrain from drinking alcohol. Women who are in the process of lactation, should stop breastfeeding and start it five after the end of taking the drug

If during the administration of the drug in patients there is a neurological symptomatology, then the drug should be discarded. At a course of treatment, which exceeds seven days, it is necessary to control the laboratory and clinical indicators.

[22], [23]

Side effects Fazijin

All side effects of Fazijin are based on the reactions of the body to the active substance in the drug. Let's consider the main side effects of the drug Fazizhin.

• Dizziness
• Convulsions
• Ataxia
• Nausea
• Peripheral Neuropathy
• Vomiting
• Diarrhea and abdominal pain
• Headache
• Metallic taste in mouth
• Skin rashes
• Allergic reactions
• Angioedema

If any of the above side effects occur, you must stop using the drug and seek medical help.

[24], [25], [26], [27]

Overdose

Overdose of the drug Fazijin may occur because of an incorrectly prescribed dose of the drug. The main symptoms of an overdose are:

• Dizziness
• Nausea and vomiting
• Strong headache
• Allergic reactions to the skin
• Increased fever and chills

The most proven treatment for drug overdose is gastric lavage and temporary discontinuation of the drug.

[32], [33], [34]

Interactions with other drugs

Incompatibility of Fazijin interaction with other drugs is not fixed. But the drug is not recommended to be used simultaneously with a number of other drugs of a similar action, as this exerts a higher pressure on the body.

The drug is incompatible with alcohol, as drinking alcohol can cause alcohol-antabusopodobnoy reaction, abdominal pain, vomiting and tachycardia. When prescribing treatment with Fazigin, the doctor checks the medicines for compatibility and only after that prescribes the admission of the course of drugs, which includes Fazizhin.

[35], [36], [37], [38]

Storage conditions

Fazigin storage conditions comply with the rules for storage of all medicinal products. Tablets should be stored out of the reach of children, if the temperature is not above 25 ° C. Also, the drug should be kept away from direct sunlight. If the rules for storage of the drug are not observed, Fazijin must be disposed of.

[39], [40], [41]

Shelf life

Shelf life of the drug Fazizhin is two years from the production date indicated on the packaging of tablets. After the expiration date, the unused medication should be discarded, as it has lost its medicinal functions. It is strictly forbidden to take the drug after the expiration date, as this will cause a number of unpredictable reactions of the body.

[42], [43], [44]