Biseptol for sore throat: how to take, dosage

, medical expert
Last reviewed: 11.04.2020

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Sore throat - a fairly common disease of the upper respiratory tract, which is accompanied by intense pain, cough, runny nose, redness of the throat, inflammation of the tonsils and lymph nodes, a sharp increase in temperature. Often a sore throat is accompanied by signs of intoxication. The main reason is a bacterial infection. In this case, the mixed infection is most often represented by the association of bacterial and viral infections with a significant prevalence of representatives of the streptococcus group. There are many treatments for angina. One of the most effective drugs is Biseptol for sore throat.

Can biseptol for sore throat?

Often in the office of the therapist one has to hear the question: “Is it possible to have Biseptol in sore throat?”. Thus, the active ingredient antibacterial affects both gram-positive and gram-negative microflora, and also relieves the inflammatory process, prevents stagnation, accelerates metabolic processes. Recovery is much faster.

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Indications Biseptol

Provides bactericidal activity against cocci. A characteristic feature is that Biseptol helps to overcome the inflammatory and infectious process caused by chlamydial infection, mycobacteria, enterococci. Also helps with fungal and yeast-like flora. Indications for use are a strong cough, burning, soreness, an increase and soreness in the lymph nodes, night snoring.

  • Biseptol for purulent tonsillitis

It is one of the most effective means for purulent tonsillitis. Biseptol has been used in therapeutic and pediatric practice for a long time.

Effective only when the cause of the development of angina is bacterial microflora.

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Release form

Only one form of biseptol release is known - roundish tablets that have a yellow tint, but mostly white. On the one hand, they are engraved and at risk. The composition includes sulfamethoxazole and trimetopril at a concentration of 400 and 80 mg, which totals 480 mg. Additionally, excipients that do not have a therapeutic effect are contained. Packed in carton packs of 14 and 20 pieces.

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If we talk about the pharmacodynamics of sulfamethoxazole, it is worth noting: it contributes to the disruption of synthetic processes in bacteria, respectively, a violation of metabolic processes occurs. Gradually, the death of bacterial cells occurs, and the inflammatory process subsides.

As far as pharmacodynamics of trimethoprim is concerned, it acts as an enhancer of sulfametaxazole activity, relieves inflammation, restores. The action of this substance is also aimed at restoring the protein metabolism of the macroorganism and disrupting the synthesis processes in the microorganism.

Generally regarded as an integrated anti-inflammatory agent. A characteristic feature is that it can have twofold consequences: it prevents the development of an intestinal infection. Side effects may develop in the form of dysbacteriosis.

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If we talk about pharmacokinetics, the first thing to focus on is the activity of the drug. It enters the bloodstream by absorption from the gastrointestinal tract within 2-3 hours after ingestion. The peak concentration in the blood is detected in about 3-4 hours. Then the substance begins to be distributed in the tissues and biological fluids, providing a therapeutic effect. First of all, it penetrates the respiratory tract and lymphoid organs, which is important in the treatment of angina.

The half-life averages 8-17 hours, and is determined by the activity of the kidneys and liver. The main part is excreted in the urine.

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Use Biseptol during pregnancy

In general, the use of any drugs, especially antibiotics, is contraindicated during pregnancy. But if the infection begins to progress, it is allowed to take Biseptol, only on doctor's prescription. The main indication for this is lacunar tonsillitis.

This disease implies that the inflammatory process and infection spread to the lacunae of the throat, which have the form and shape of bags filled with purulent contents. The inflammatory process develops in these lacunae, there is a reproduction and development of bacterial microflora. The lacunar form is particularly difficult to treat, since almost the entire pathological process takes place in the gaps and is not available to many drugs. Also, microorganisms multiply there much more efficiently, form a howl microenvironment (biofilm). But Biseptol has the ability to penetrate into the lacunae, destroy the microbial biofilm, remove the inflammatory process.

It should be understood that the risk of not being treated should be much higher than all possible risks of therapy. Dosage is strictly individual.


There are not many contraindications, but all of them are serious enough, you have to take it into account. Not recommended for use in renal failure, diseases that are in remission (creates an additional burden, and the kidneys suffer from it in the first place). Also, there is a load on the urinary system, the drug may cause intoxication, edema syndrome. For the same reason, it is advisable to prescribe a dream to pregnant women, children under 3 years of age, with increased individual sensitivity, diseases of the stomach, intestines, especially gastritis, ulcers, and pre-ulcer conditions.

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Side effects Biseptol

It is considered a proven and relatively safe drug, so side effects are rarely observed. Not excluded violations of the kidneys, liver. Observed urinary disorders or excretion of bile, a violation of digestion. As a result, an imbalance of metabolic processes, dysbacteriosis, which is accompanied by nephritis, pyelonephritis, cystitis, glomerulonephritis, and even renal failure develops. Edema, dermatitis, eczema, urticaria develop.

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Dosing and administration

Assign inside. The tablet should be swallowed (washed down with clean water). The dosage is determined by age, based on the fact that the standard dose is 480 milligrams. Up to 5 years, prescribe half the standard dose per day, from 5 to 12 years, 480 mg. After 12, it is allowed to use 960 mg per day. For safety reasons, the method of application, the optimal dose should be selected only by a doctor.

  • How to take Biseptol 480 for a cold?

One of the most common questions to hear from patients is the question "How to take Biseptol 480 for a cold." This is quite difficult, because you need to take into account many factors.

First, Biseptol may be effective if the cold is caused by bacterial microflora. When the cold is caused by viral microflora, the result will not be.

Secondly, you need to choose the right dose. This is not difficult, since one tablet is a daily dosage.

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Biseptol for angina in adults

Biseptol is recommended for purulent and lacunar angina in adults. Allows you to quickly eliminate the inflammatory and infectious process. Purulent tonsillitis is a direct indication for the appointment of Biseptol, since the purulent process is almost always caused by bacterial microflora. Most often, Biseptol has exactly the antibacterial effect, which allows you to quickly get rid of the infectious and purulent process.

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Application for children

Children can use biseptol, but not before they turn 3 years old. The approximate treatment scheme is selected on the basis of laboratory tests, anamnesis data. It is recommended to accept at a strong quinsy, its complicated forms. Enough half a tablet per day.

  • Biseptol when coughing in a child

Biseptol makes sense to prescribe when coughing a child, provided that the cough is caused by a bacterial process, and is a consequence of the development of angina. If the cough is due to a viral process, or an allergic reaction, the drug will not only not have the expected effect, but may even worsen the condition. Therefore, it is important to correctly diagnose and determine the etiological factor.

At the same time, it is worth noting that in no case it is impossible to make a decision on the appointment of a child of this drug, since this can be fraught with serious consequences and complications. Be sure to consult with your doctor, who on the basis of anamnesis, as well as the results of the examination, laboratory studies will prescribe the appropriate treatment, select the dosage of the drug.

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Overdosing is accompanied by abnormalities in the digestive system: nausea, vomiting, diarrhea, flatulence. There are signs of poisoning. When the first symptoms of an overdose appear, it is necessary to provide emergency assistance as soon as possible: induce vomiting, flush the stomach. This will eliminate the substance from the body. You must also immediately call the ambulance. In polyclinic conditions, detoxification, rehabilitation, support therapy is usually performed.

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Interactions with other drugs

Relatively well tolerated by the body, there is no specific interaction with other drugs. When analyzing reviews of the drug, it was possible to find a few mentions, that while taking with other antibiotics, overdose may develop. The instructions indicate that the drug is able to react with antiviral agents.

It is not recommended to combine together with secretion blockers, since the combined use of these agents inhibits the excretory processes and impairs kidney function, causes dysuric disorders, urinary syndrome, inflammation in the kidneys, and diseases of the genitourinary system. Against the background of co-administration with vitamins, vitamin-mineral complexes and biological additives, a reaction is observed that leads to a decrease in antibacterial activity.

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Storage conditions

Biseptol should be stored in original packaging. Usually storage conditions are prescribed in the instructions. You can store the drug in room conditions, it is possible in the refrigerator, on the door, on the bottom shelf. It is there that the optimum temperature is found, which will allow to keep active those components that are part of the preparation. It is important to keep the tablets in a dry place. The temperature should not exceed 25 degrees. At the same time direct sunlight should not fall.

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Shelf life

Biseptol can be stored for two years from the date of production. You should not take the drug if the shelf life has expired, since there will be no effect on the treatment.

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The closest analogues of the drug is co-trimoxazole, sulfanilamide. These are pure substances that are part of Biseptol. You can also replace the drug with other antibiotics, for example, rifampin, amoxiclav, amoxicillin, ampicillin.

  • Co-trimoxazole

Co-trimoxazole is taken at 80 mg per day. It should drink at least 10 days. It should be borne in mind that the drug has anticoagulant activity, dilutes the blood. Also, it should not be taken in combination with anticoagulants, since their activity is sharply reduced. Hepatic metabolism is also inhibited, as a result of which renal pathologies can develop, intoxication of the organism. Often prescribed in conjunction with anticoagulants, especially if the person has liver problems.

It is a broad-spectrum antibiotic that is active against gram-positive and gram-negative microorganisms. Usually prescribed at 500 mg per day (for an adult). Amoxicillin is not recommended for children under the age of 12, since it causes dysbacteriosis and can lead to impaired metabolism and endocrine processes.

  • ampicillin

Considered as an analogue of biseptol. It is prescribed for various forms of angina (most often for the lacunar, follicular form). Ampicillin is recommended to take 500 mg per day.

It is a good alternative to Biseptol and other similar drugs. Amoxiclav is prescribed for the treatment of diseases of the respiratory system, with sore throat, cough, rhinitis. The main condition of effectiveness is to prescribe in the treatment of diseases of bacterial origin. In relation to viral diseases is not effective, like any other antibiotic. Available in the form of tablets dosage of 500 mg. The daily dosage is one tablet per day, because it is a drug of prolonged action. The course requires only 3 tablets. It should be borne in mind that the drug can cause dysbiosis, so it is often prescribed along with probiotics. Caution is prescribed to persons suffering from liver pathologies (it is better to take along with hepatoprotectors).

For angina, various throat sprays have a positive effect. One of these tools is inalipt. It is prescribed for diseases of bacterial genesis, since it not only has an antibacterial effect, but also moisturizes the mucous membrane. Also, all the sprays normalize the microflora, restore the mucous membranes. Cough is significantly reduced, inflammation, redness disappears. Indications for use of ingalipt - any form of angina: catarrhal, follicular, lacunar, fibrinous. It is also recommended if there is a risk of complications, including diseases of the lower respiratory tract (bronchitis, pneumonia, tracheitis).

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If we analyze the reviews, it can be noted that positive ones prevail among them. Negative reviews are extremely rare, and are mainly observed only with improper use of the drug, and with exceeding the dosage. Biseptol with angina significantly relieves the condition, quickly relieves pain, inflammation. After 2-3 days, cough decreases, lymph nodes decrease, redness and swelling of the throat go away. Apply to both children and adults. A characteristic feature is that the drug acts quickly. Already after about 1-3 hours there is a noticeable improvement in the condition. Many feel healthy in a day. Full recovery usually occurs on the 5th day; this is the minimum course of treatment.


To simplify the perception of information, this instruction for use of the drug "Biseptol for sore throat: how to take, dosage" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.

Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.

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