Amoxicillin with purulent sore throat: does it help, instructions for use

Antibiotics are very common medications that are often used to treat purulent sore throats. Most patients prescribe antibiotics from the penicillins or cephalosporins - for example, Amoxicillin, Ampicillin, Cephalexin. In this case, Amoxicillin in angina is often an antibiotic under the number "one" - this drug is affordable, effective and relatively safe.

Is it possible to have Amoxicillin in a sore throat?

Angina is a disease in most cases of microbial origin, in which palatine tonsils are inflamed. In angina (in medical circles the disease is called "tonsillitis") antibiotics are prescribed almost always, since very often the disease causes complications: disorders of kidney function, rheumatism, inflammation of the middle ear, etc.

What antibiotic to choose, the doctor decides - after all the preparation should be equally effective and safe. Often the drug of choice is Amoxicillin, because it has a wide range of antimicrobial activity and helps to cope with an insidious disease.

If we consider that the angina is most often provoked by bacteria such as streptococci and staphylococci, then treatment with drugs from the penicillin group (and such includes Amoxicillin) is fully justified. Amoxicillin in angina should not be taken only when the patient has the prerequisite for the development of an allergic reaction to drugs of the penicillin group. In this situation, the doctor prescribes other drugs: fluoroquinolones, macrolides, etc.

Indications of the amoxicillin in angina

And yet antibiotics are not always present in the treatment regimen of angina. To prescribe these drugs you need to have clear indications. In what cases, in particular, amoxicillin is prescribed?

• In the presence of visible purulent deposits on the surface of the tonsils.
• With a pronounced prolonged fever.
• With increasing submandibular lymph nodes.
• When there are other nonspecific symptoms for angina.

In the cases listed above, the doctor will definitely recommend an adult patient antibiotic therapy - even without waiting for the results of laboratory tests. It is important only not to confuse the symptoms of angina and a viral disease - for example, the flu. After all, as you know, antibiotics against the virus are powerless and can only do much harm.

[1], [2]

Amoxicillin with purulent angina and herpes

Purulent angina is a direct indication for the administration of an antibiotic, such as Amoxicillin. Purulent discharge is considered the main sign of a microbial invasion, which can be stopped with antibiotics.

It makes no sense to treat sore throat caused by a virus or fungus. By the way, fungal tonsillitis is often mistaken for purulent sore throat, since the fungal infection characteristic of fungal infection resembling cottage cheese can be confused with a purulent film.

Amoxicillin with herpes angina will also be ineffective, because herpes is a viral infection, which can be treated only with special antiviral drugs. The herpes virus is able to penetrate into the DNA of the cells and multiply there. Antibiotics, on the other hand, can not enter cells and destroy viral DNA - only antiviral drugs are capable of this.

Amoxicillin can be used for herpes sore throat if this disease, against the background of the virus, is accompanied by a secondary bacterial infection. In addition, an antibiotic can be prescribed with a significant change in blood composition and a prolonged severe fever to avoid complications.

[3]

Release form

Amoxicillin is represented by several medicamentous forms:

• Capsulated preparation of 250 mg (the package contains 16 capsules).
• Capsulated preparation of 500 mg (the package contains 16 capsules).
• Granular preparation for the manufacture of suspension (packaging - bottle).

Amoxicillin 500 with angina is the most common because of the convenience of admission: adult patients are most often treated with a standard treatment regimen that provides for Amoxicillin 500 three times a day, one capsule.

[4], [5], [6], [7]

Pharmacodynamics

Amoxicillin is a typical representative of the penicillin group of antibiotics. This drug successfully fights with streptococci, staphylococci and with a mixed infection.

The mechanism of action of this antibiotic in angina is as follows: getting into the inflamed tissue in the zone of development of microbial infection, Amoxicillin inhibits the production of a substance without which it is impossible to build a wall of a microbial cell. As a consequence, the pathogenic microorganism loses its ability to develop and multiply. If the effect of the antibiotic continues, the microbe also loses the function of restoring its own cell wall, which leads to its death.

Amoxicillin in angina is used in uncomplicated clinical situations, when the disease has an exclusively microbial character, confirmed by symptoms and laboratory findings .. With respect to fungi and viruses, the antibiotic is powerless.

[8], [9], [10]

Pharmacokinetics

Amoxicillin with angina acts almost immediately. This antibiotic has a high bioavailability: about 93% of the intake into the bloodstream after ingestion. This is due to the rapid and effective action of the drug, which is quickly distributed in most tissues and fluids in the body.

Due to the high bioavailability, there is no need for large dosages of the drug. If we compare the degree of such bioavailability with other antibiotics, we can see that, for example, it is 50% in Phenoxymethylpenicillin, and in Ampicillin - no more than 40%. Therefore, the dosage of these drugs is always high.

Amoxicillin has a weak connection with plasma proteins - this connection is estimated at 17%.

Limit concentrations in the plasma after a single dose of 250 mg or 500 mg are detected for 1-2 hours. The half-life is 1-1.5 hours.

The drug is practically not metabolized. It is excreted from the body mainly through the urinary system, and in a smaller volume - with caloric masses.

The presence of food in the stomach does not affect the quality of absorption of Amoxicillin.

[11], [12]

Dosing and administration

Amoxicillin should be taken three times a day: after breakfast, after dinner and after dinner.

With uncomplicated normal angina, 500 mg of antibiotic is prescribed for each appointment.

The course of Amoxicillin with angina usually lasts from five to seven days. If the disease is protracted and there are various complications, the doctor may prescribe an increased dosage of 750 mg three times a day.

How many times do I drink Amoxicillin in a sore throat? The drug is taken three times a day, regardless of the dosage.

How many days to drink Amoxicillin in angina? Treatment can last from five to fourteen days, depending on the complexity of the disease. In any case, the reception of the antibiotic continues for another two to three days after the patient's condition is normalized.

[17], [18], [19]

Amoxicillin with angina in adults

For the treatment of angina in adults Amoxicillin is used only in case of development of a purulent process. Purulent discharge indicates the presence of microbial damage, which can be stopped using a quality antibiotic, in this case, Amoxicillin.

It makes absolutely no sense to prescribe an antibiotic when infected with viruses or fungal infection - when the tonsils are clean, without purulent plugs and plaque.

Do not take Amoxicillin to people who suffer from ulcerative inflammatory diseases in the stomach or intestines, as well as with lymphocytic leukemia and infectious mononucleosis.

If the doctor has prescribed Amoxicillin for the treatment of angina, then you should strictly adhere to the prescribed treatment regimen. You can not independently make changes in the indicated dosage, frequency and frequency of taking the drug, and also finish the treatment earlier than the doctor will allow. Such rash independent actions can lead to the development of bacterial resistance, which will lead to the return of painful symptoms and to further difficulties in treatment.

[20]

Amoxicillin in children with angina

In childhood, the use of Amoxicillin for the treatment of angina is not uncommon. After 12 years, the child's dosage of an antibiotic is equated to an adult - the same applies to children from 10 years old, whose weight is above 40 kg.

Small children Amoxicillin offer not in capsules, but in suspension. The dosage is determined as follows:

• children 5-10 years old receive 250 mg of Amoxicillin in the morning, after dinner and in the evening;
• children 2-5 years old receive a dose at the rate of: 20 mg of the drug per 1 kg of weight (this is the daily amount, which should be divided into three doses).

Amoxicillin in angina can be applied to breast, and even newborn babies. For infants, the dosage is calculated individually, and the total duration of antibiotic therapy is 12 days.

To prepare a suspension of Amoxicillin for a baby, add water to the bottle with the drug (to the dash line) and mix well, shaking gently.

The resulting suspension can be stored for a short time: no more than two weeks in a cool place.

[21], [22], [23], [24], [25]

Use of the amoxicillin in angina during pregnancy

A doctor should decide whether to use Amoxicillin as a pregnant woman. Before prescribing an antibiotic, he takes into account the following facts:

• Amoxicillin is able to overcome placental protection - and in volumes larger than some other antibiotics (eg, Apmicillin).
• The proven facts of the influence of Amoxicillin on the development of birth defects in newborn babies are not yet available.
• Amoxicillin can be rapidly excreted by the body.
• Side effects during treatment with Amoxicillin may adversely affect the course of pregnancy and fetal development.

Given all of the above facts, you can say only one thing: Amoxicillin in angina can be appointed only in cases when you can not do without it. In all other cases it is better not to risk: from treatment with an antibiotic should refrain.

In the first half of pregnancy the use of Amoxicillin is most undesirable, and in lactation it is prohibited.

Self-administration of Amoxicillin for the treatment of angina is strictly prohibited.

Contraindications

Contraindications for taking Amoxicillin with angina are relatively few. Nevertheless, they are available, and any patient who needs such treatment should be aware of them.

• Hypersensitivity to any of the drugs of the penicillin series.
• Allergic reaction to antibiotics from a number of penicillins or cephalosporins (possible the development of a cross reaction).
• Lymphocytic leukemia and infectious mononucleosis.
• Relative contraindications are:
• acute inflammatory and ulcerative-erosive processes in the digestive tract;
• severe violations in the work of the liver and kidneys;
• pregnancy.

If Amoxicillin is prescribed during lactation, then breastfeeding is temporarily stopped. Most mothers return to breastfeeding approximately five days after the last administration of the antibiotic.

[13]

Side effects of the amoxicillin in angina

The list of adverse symptoms that may occur during the administration of Amoxicillin is relatively small. The most common such manifestations are:

• rash on the skin, itching, redness, allergic swelling;
• the appearance of crystals in the urine;
• a slight increase in liver enzymes;
• transient leukopenia, anemia, transient increase in prothrombin time;
• a state of excitement, pain in the head, sleep disturbances.

As a rule, all listed symptoms are temporary. They pass without additional treatment, immediately after stopping the antibiotic Amoxicillin.

[14], [15], [16]

Overdose

The intake of a large amount of antibiotic, as a rule, is not accompanied by any specific symptoms. It is possible to develop side effects.

If there is a suspicion of overdose, it is recommended to wash the patient's stomach and give a sorbent.

If the accepted amount of Amoxicillin is too high, then the doctor can apply hemodialysis on the background of symptomatic therapy.

[26], [27], [28], [29]

Interactions with other drugs

It is undesirable at the same time to take Amoxicillin and Allopurinol: there may be a rash on the skin.

Amoxicillin oppresses the effect of contraceptive drugs for internal use.

Do not combine Amoxicillin with anti-acid drugs and bacteriostatic antibiotics (Chloramphenicol, Tetracycline, etc.): these drugs negatively affect the absorption and effectiveness of Amoxicillin.

Probenecid inhibits the excretion of Amoxicillin by the kidneys.

When combined, Amoxicillin and anticoagulants will increase the duration of bleeding and the prothrombin index.

Storage conditions

Capsules and suspension Amoxicillin can be stored under room conditions, in a place difficult to reach for children.

[30], [31], [32]

Shelf life

Capsules and granules for the preparation of Amoxicillin suspension are retained for three years. The finished suspension is stored for at least two weeks.

[33],

Reviews

Practically all patients who had to treat angina Amoxicillin, indicate the high effectiveness of this antibiotic. It is not for nothing that the drug is considered an antibiotic of choice in purulent sore throat: it has a pronounced effect, has a small number of side effects, is affordable and practically safe. Only in rare cases, Amoxicillin causes dyspepsia, colitis, or allergy.

The most important point during treatment with Amoxicillin is not to break the rules of antibiotic therapy. So, you can not arbitrarily interrupt the treatment prescribed by the doctor, you can not use the antibiotic outside (instead of ingesting it, for example, for rinsing), you can not adjust the dose and the frequency of reception. All these disorders lead to the fact that bacteria develop resistance to antimicrobial drugs, which leads to the development of diseases, which is very difficult to cure.

If you start treatment as soon as possible and take the drug Amoxicillin correctly (according to the doctor's prescription), then within a few days you can cure angina without complications.

What to replace Amoxicillin in angina?

If the doctor prescribed Amoxicillin, but he was not in the pharmacy, then you can buy an antibiotic analog instead. Such antibiotics can be:

• Amoxyl tablets;
• Amophast tablets;
• capsules of B-Mox;
• capsules or Gracimol powder;
• capsules or powder Gramox;
• Iramox capsules;
• granules of Iramox;
• Ospamox (available in granules, powder, capsules or tablets);
• pills Flemoxin;
• capsules or powder Hiconcil.

In addition, you can use and combined drugs, which include Amoxicillin. Amoxiclav, Amoxil, Augmentin, Betaklav, Teraklav and Flemoklav are the most popular among such preparations.

Amoxicillin or Azithromycin in angina?

Which of the antibiotics is better is a relative question. Most often, doctors choose Amoxicillin. The fact that this antibiotic is able to combine all the properties that provide the highest possible efficiency, accessibility and safety of treatment. Therefore, doctors unequivocally recommend the treatment of angina with the drug Amoxicillin.

However, if the tests indicate the resistance of bacteria to penicillins, or the patient has an allergy to penicillins, then in such cases, Azithromycin is uniquely chosen - this drug is in no way inferior to Amoxicillin in the spectrum of antimicrobial activity.

[34],

Amoxiclav or Amoxicillin in angina?

If you disassemble the pharmacological properties and composition of the drugs, it turns out that Amoxiclav - a more versatile and powerful antibiotic, compared with Amoxicillin. Amoxiclav even kills those microbes that are resistant to the antibiotics of the penicillin series. However, in practice, the effect of these drugs is almost the same - angina is cured about the same time period.

If the bacteria are insensitive to the action of penicillins, the doctor will never prescribe either Amoxiclav or Amoxicillin.

In the event that Amoxicillin is prescribed for angina, but it is not in the pharmacy, it is possible to replace this drug with Amoxiclav.

[35], [36]