Avamis for adenoids: treatment regimen

Adenoids cause a lot of trouble for sick children and their parents. The disease, of course, needs to be treated. If no measures are taken, it can become chronic and cause numerous complications. There are many ways to treat adenoids, relieve symptoms, and alleviate the body's condition. But the disadvantage of most of the remedies is that most of them are carried out exclusively in a doctor's office or in a hospital. But thanks to the efforts of pharmacists, today it is possible to use a new remedy for treating adenoids at home. The drug Avamis for adenoids in children is quite effective and in demand today.

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Indications of avamis for adenoids

Indications for the use of Avamis are the first signs of adenoiditis. It is used if the child has difficulty breathing, if there is constant snoring, especially at night. If the child constantly breathes through the mouth, even during the day. Indications for use are persistent runny nose that does not respond to treatment with any other means. Long-term allergic reactions, constant rhinitis force you to turn to Avamis.

Adenoiditis can be suspected in a child independently. It is indicated by quite vivid and specific signs. The doctor usually makes a diagnosis quite quickly. It does not require additional differential diagnostics, a general examination and the results of laboratory and instrumental research are enough.

Avamys is used not only for the treatment of adenoids, it can also be used to treat allergic and vasomotor rhinitis, sinusitis, and other purulent and inflammatory diseases of the nasopharynx, pharynx. It can be used to treat otitis, tubootitis, which are usually a complication of respiratory diseases.

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Release form

This medicine has only one form of release - nasal spray. It is released in the form of a bottle of unusual design, which contains a dispenser and a sprayer. Each dose has the same volume and concentration. In the center of the bottle there is a transparent window, which allows you to control the amount, the remainder.

It is a hormonal agent that has a local effect, belongs to the glucocorticoid series. It has an antiallergic and anti-inflammatory effect. The composition also additionally includes cellulose, polysorbate, purified water and dextrose.

The medicine is produced under the name Avamys. This is a product of English manufacture. There are also its analogues, which are no different except for the country of manufacture. Nasonex is produced in Belgium, and Flixonase is produced in Poland. These drugs are completely identical in composition and contain the same dosage. They are used according to the same scheme as Avamys, in the same concentration. The cost may differ.

Pharmacodynamics

Avamys is based on the action of hormonal agents. They have an exclusively local effect on the mucous membrane of the nasopharynx, as well as directly on the adenoids. The drugs do not have a systemic effect. They penetrate into the blood in minimal quantities and are immediately metabolized in the liver. The drugs do not accumulate in the blood plasma. This explains their relative safety. The drug can be prescribed even to children.

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Pharmacokinetics

The drug is characterized by its ability to be partially adsorbed by nasopharyngeal cells. It is characterized by high affinity and biological activity. Due to such a property as affinity, the drug has only a local effect on the body. The absence of systemic action determines its relative safety. It does not affect other internal organs and systems.

Affinity implies affinity with glucocorticoid hormone receptors and ensures high biological availability of the drug in the spray area, i.e. in the nasopharynx. The active substance selectively binds only to the active sites of the necessary analyzers, which significantly narrows the spectrum of its action. Due to this, unwanted reactions and side effects are blocked. Unwanted allergic reactions and intolerance are prevented. A high degree of affinity also provides for a strong and long-term connection of the drug with receptors, due to which the period of action of the drug is significantly increased.

This increases the selectivity of the drug and reduces the negative effects of taking hormonal drugs. Due to the fact that the nasal cavity is irrigated, and not instilled, a larger surface area is covered by the action of drugs. Since the drug binds to sensitive receptors, this eliminates the possibility of foreign agents attaching to them. Thus, the risk of allergic reactions is significantly reduced. Due to this circumstance, the drug can be prescribed even to children.

In severe renal failure, the drug is contraindicated. This is explained by the fact that it penetrates the blood in small quantities, then enters the liver and is processed there by an extensive metabolic pathway. In this regard, the load on the liver increases sharply.

Dosing and administration

For children aged 2 to 12 years, the drug is prescribed in one dose no more than once a day. Upon reaching 12 years of age, as well as for adults, 2 doses are recommended. Daily use, the duration of treatment depends on many factors and is determined by the attending physician. The duration of treatment depends on the results of laboratory and instrumental tests.

Use of avamis for adenoids during pregnancy

Avamys is a hormonal drug. But it has a feature - it is excreted from the body quite quickly, does not linger in tissues and has a high selectivity of action, binding only to receptors of glucocorticoid hormones of the nasopharynx. Thus, the systemic effect of the drug is excluded. Drugs with local action can be considered relatively safe. In addition, it does not cause addiction and drowsiness. But the advisability of its use during pregnancy and breastfeeding is still a controversial issue.

High selectivity and local action do not exclude the drug from entering the blood in minimal doses. The drug is also able to penetrate the transplacental barrier in minimal, virtually harmless concentrations. However, pregnant women already have a high hormonal imbalance, and the fetus is extremely sensitive to any concentrations of foreign substances.

Most experts are inclined to believe that it is better not to use the drug for pregnant women unless absolutely necessary. Avamys is used when other methods of therapy are ineffective.

Contraindications

The drug is contraindicated in case of severe allergy and individual intolerance to its components. In case of bronchial asthma, it can worsen the condition and cause suffocation. Anaphylactic shock, local allergic reactions, angioedema, and urticaria may develop. This is mainly observed in case of overdose.

The drug is not recommended for children under two years of age. The drug is also contraindicated for people who suffer from liver failure. A small amount of the drug enters the systemic circulation and penetrates the blood. At the same time, a small amount of the drug enters the liver and increases the load on it.

The drug is not recommended for use in cases of a tendency to nosebleeds and damage to the nasal mucosa. It is also recommended to refrain from using the drug in the postoperative period.

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Side effects of avamis for adenoids

With correct and strict adherence to the treatment regimen and dosage, side effects are practically not observed. In rare cases, dryness and burning of the nasal passages, sore throat may be observed. With prolonged use, allergic reactions may be observed against the background of excessive dryness of the mucous membrane. Coughing and sneezing may also occur. If a person has a tendency to bleeding, nosebleeds may be observed. In case of overdose or violation of the treatment regimen, nasal erosions and ulcers may occur.

People with bronchial asthma and allergies may develop swelling and anaphylactic shock. All this is usually accompanied by a headache.

Overdose

Overdose may be caused by simultaneous use of Avamys with other hormonal drugs. Do not use the drug during treatment with glucocorticosteroids. Sometimes, when dosing, irritation, disturbance, and changes in the function of the adrenal glands may be observed. This may cause significant growth retardation. Therefore, during long-term treatment with Avamys, it is necessary to regularly measure the child's height.

Interactions with other drugs

The drug should not be used together with other hormonal drugs, as an overdose occurs. It is not compatible with drugs such as ritonavir and ketoconazole. When taking these drugs together, an overdose is also observed, which manifests itself in the form of increased heart rate, weakness, and a drop in blood pressure.

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Storage conditions

The drug is stored in a dry place protected from light. Store in the original packaging.

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Shelf life

In packaged form, the drug can be stored for 2 years from the date of production. In unpacked form, the drug can be stored for 3-4 months.

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Reviews

Reviews of the drug are quite contradictory. Some claim that the drug is effective for runny noses and colds. 1-2 inhalations per day are enough and the child feels much better. Some claim that the drug does not have the desired effect, and addiction develops to it.

Many parents write that before using the drug, their child had been ill for a long time, bothered by adenoids, frequent colds. There were numerous adenoids. For those children whose adenoids were not removed, the drug allows them to control the condition and reduce the symptoms of the disease. Those children whose adenoids were removed with Avamys tolerate the postoperative period more easily. The risk of complications is significantly reduced, and their health is much better.

However, most parents are inclined to believe that Avamys is an effective remedy. There are reviews according to which Avamys helps even with third-degree adenoids. Some use the drug for prevention, this helps prevent a runny nose, inflammation of the adenoids. The child breathes calmly, through the nose. Does not snore at night. During examination, doctors find a decrease in the size of the adenoids. The drug also helps relieve swelling, as a result of which the adenoid tissue decreases and the inflammatory process decreases. The duration of treatment for most patients is a month. Many complain about the high cost of the drug, but agree that the price matches the quality.

If we analyze the reviews of professionals who prescribe Avamys to their patients, it is worth noting: they consider it a successful drug of choice, which is effective and safe if all precautions are taken. The drug is hormonal, but it has a gentle effect. The effect of the drug is local.

Although it should be noted that most doctors are still experimenting with this drug, since there is no approved evidence base and full randomized studies have been conducted yet. There is also no standardized method for taking the drug, which would indicate how and in what dosage the drug should be used.

Avamys is prescribed for adenoids in children to relieve inflammation. It does not provide a direct effect on reducing adenoids, but only indirectly by eliminating swelling and inflammation. This makes it possible to control the condition, prevent inflammation and eliminate symptoms. In many children, adenoids are restored to normal sizes.