Dolgit

Dolgit is used for inflammation, as well as for degenerative processes in the musculoskeletal system.

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Indications Dolgit

Dolgit is used for inflammation, as well as for degenerative processes in the musculoskeletal system. These diseases include symptoms of gout, arthritis, humerus periarthritis, Bechterew's disease, deforming osteoarthritis, osteochondrosis with radicular syndrome, radiculitis, tendinitis, tendovaginitis, bursitis, lumbago, sciatica. In addition, medications are indicated for use in muscle pains - myalgia, which are caused by rheumatic and non-rheumatic causes. Medicines are indicated for injuries that do not negate the violation of the integrity of the skin - dislocations, sprains and ruptures of muscles, ligaments, as well as bruises, posttraumatic swellings of soft tissues.

Release form

The drug Dolgit is available in the form of a gel and cream for external use. The gel is packaged in aluminum tubes, which inside have a protective lacquer coating, for twenty, fifty or one hundred grams. Tubes are closed with protective membranes and screwed with a plastic cap. Each tube is placed in a cardboard box together with the insert-instruction. The cream is packaged and packaged in a similar way.

Gel Dolgit differs transparent and colorless consistency, with a certain smell. One hundred grams of gel contains five grams of ibuprofen, which is an active substance. Also in this same amount of gel there is a certain content of isopropanol, dimethylhydroxymethyldioxole, poloxamer a, b, c, triglycerides of medium chain, purified water, ethereal lavender oil, ethereal neroli oil.

Cream Dolgite differs a homogeneous and soft consistency, with white or cream color. Has a slight specific smell. A hundred grams of cream contains five grams of ibuprofen, which is an active substance, as well as a certain amount of triglycerides of medium-chain, purified water, glyceryl monostearate, propylene glycol, macrogol-100-stearate, macrogol-30-stearate, xanthan gum, methylparahydroxybenzoate sodium, lavender oil, oil.

Pharmacodynamics

The drugs have local anesthetic and anti-inflammatory effects. Are able to suppress the production of mediators of inflammatory processes. The cyclooxygenase 1 and 2 are blocked selectively, inhibiting the production of prostaglandins, as well as prostacyclin and thromboxane. The analgesic effect is most effective at painful sensations caused by inflammation. The dolgite is able to ease the pains that arise during moments of rest and movement, and also increase the volume of movements.

Ibuprofen is able to reduce the level of platelet aggregation in the area of inflammatory processes. Also, the substance is distinguished by the quality of the decrease in the migration of leukocytes and the release of lysosomal enzymes in the area of inflammation.

Pharmacokinetics

With topical application of drugs, ibuprofen is able to penetrate into other subcutaneous layers and reach subcutaneous tissue, muscles, joints, synovial fluid and reach therapeutic concentrations there. Direct distribution of the active substance into the necessary tissues contributes to the therapeutic effect. The active substance is found in small amounts in serum. The amount of ibuprofen that penetrates into the synovial fluid is up to two μg per ml.

Dosing and administration

For the gel: the drug is used externally. From five to ten centimeters of the extruded gel is applied to the required skin area and rubbed carefully and lightly until the preparation absorbs into the skin. This procedure should be conducted from three to four times a day. The duration of the course of treatment is from two to three weeks.

For the cream: the medicine is for external use. It is applied three or four times a day to the desired area of the skin with rubbing movements until the drug is absorbed into the skin. It is necessary to use a strip of cream with a length of four to ten centimeters. The course of therapy is two to three weeks.

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Use Dolgit during pregnancy

For the gel: it is forbidden to use the drug in the third trimester of pregnancy.

For cream: do not use the drug during pregnancy and lactation period.

Contraindications

For the gel:

• The presence of hypersensitivity to active or auxiliary substances, as well as other non-steroidal anti-inflammatory drugs.
• Presence in an anamnesis of a bronchial asthma.
• There are allergic reactions in the form of hives, rhinitis, which causes the use of acetylsalicylic acid.
• Presence of wet dermatoses, eczema, skin integrity disorders, infected wounds and abrasions in the necessary area of skin.
• The patient's age is up to twelve years.

For cream:

• All of the above, as well as the age of the patient to fourteen years.

Side effects Dolgit

Dolgit is well tolerated by patients.

• Rare occurrences of side effects show the occurrence of local allergic reactions in the form of redness, swelling, rashes, itching, burning sensation and tingling sensations.
• Sometimes there may be signs of bronchospasm.
• The use of the drug for a long time can activate systemic side effects, the development of which should stop using the drug and seek the help of specialists.

Overdose

• There is no description of cases of overdose.
• If Dolgit got into by accident, it is important to provoke symptoms of vomiting, and also to wash the stomach and use activated carbon orally.
• If necessary, symptomatic therapy is used.

Interactions with other drugs

For the gel: there is no description of drug interactions with the drug. But it is important to understand that ibuprofen, when used locally, can have a systemic effect. Therefore, with its simultaneous use with other non-steroidal anti-inflammatory agents, there may be an increase in side effects.

For a cream: consultation of the expert before application of a medicine is necessary in case of use of other medicinal preparation.

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Storage conditions

Dolgit - in a place inaccessible to children, at a temperature of 15 to 20 ° C.

Shelf life

Dolgit is stored 36 from the moment of production.