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Dasikon
Last reviewed: 23.04.2024
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Dasikon refers to antibacterial drugs of the fluoroquinolone group. Antimicrobial drug is used systemically for infectious and inflammatory processes.
Indications Dasikon
Dasikon is prescribed for infectious and inflammatory diseases, which are caused by bacteria susceptible to gatilofloxacin (cystitis, cervical gonorrhea, chronic bronchitis, bacterial sinusitis, infections of the genitourinary system, etc.).
[1]
Release form
Dacicon is available as a solution for drip.
Pharmacodynamics
The active substance Dacikon is gatilofloxacin, which is active against many gram-negative and gram-positive bacteria. The antimicrobial effect of the medication is due to inhibition of topoisomerase IV and DNA-gerase.
Laboratory tests in vitro showed that the drug is harmful to a large number of microorganisms, including enterobacteria, morgan bacteria, Klebsiella, citrobacter, Pseudomonas aeruginosa, Salmonella, Yersinia enterocolitis, Campylobacter, gonorrhea, most staphylococci, etc.
Dacicon is not effective against bacteroides, clostridia, fusobacteria.
Pharmacokinetics
Bioavailability of Dacicon is 96%, in the blood the maximum concentration is reached on average after one to two hours after the administration of the drug.
The antibiotic binds to blood proteins 20%, it is distributed throughout the body to all tissues and fluids.
Excretion occurs unchanged in kidneys (about 70%) for two days, about 5% is excreted with feces. The average half-life is 8 to 14 hours, regardless of the dosage.
Dosing and administration
The medicine is prescribed by the doctor taking into account the disease.
Usually it is prescribed 400 mg per day, the duration of treatment is 1 to 2 weeks.
In uncomplicated infections, the drug is prescribed once (400 mg), further use is determined by the doctor. With endocervical and rectal gonorrhea in women, gonorrhea in men Dacicon is administered once (400 mg).
The drug is administered once a day, patients who are prescribed artificial blood cleansing, in which the rate of blood purification is reduced, a dose adjustment is recommended.
[4]
Use Dasikon during pregnancy
The medicine is prescribed to pregnant women only in case of emergency.
Contraindications
Dacicon is not used in cases of increased susceptibility of the body to the antibiotics of the fluoroquinolone group, during pregnancy, before the age of 15, in patients with a deficiency of glucose-6-phosphate dehydrogenase.
[2]
Side effects Dasikon
Dacicon, as shown by clinical trials, is tolerated well by patients. In some cases, there was a feeling of nausea, upset of the chair, dizziness, headaches, inflammation in the vaginal mucosa.
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Overdose
Cases of overdose Dacicon was not recorded. When symptoms of an overdose (vomiting, weakness, dizziness, etc.) shows symptomatic therapy, it should be maintained in the body a sufficient level of water-salt balance.
Purification of blood by an artificial method is ineffective.
Interactions with other drugs
Dacicon in combination with the preparations of the quinolone group increases the level of theophylline in the blood, which can cause a number of side effects. When administered simultaneously with probenecid, gatifloxacin is injected into the systemic circulation.
Dasicon increases the effect of drugs that cause blood clotting.
Storage conditions
The medicine should be stored in a dry place, protected from direct sunlight. The drug should be protected from small children.
When freezing, the therapeutic effect of the drug is lost.
Shelf life
Dasikon is suitable for two years from the date of manufacture. The drug can not be used after expiration or storage conditions.
Attention!
To simplify the perception of information, this instruction for use of the drug "Dasikon" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.