Kulgan

Kalgan is a natural medicinal product widely used in gastroenterology, gynecology, dentistry, dermatology, ENT-practice and many other fields of medicine.

According to ATS coding, kalgan refers to medical products that are capable of having a therapeutic effect on the digestive system, as well as metabolic processes in the body.

The international name of the drug is Tomentilla erecta. In fact, kalgan is one of the varieties of perennial plants - lapchatka (pink family).

Kalgan is ideal for complex treatment as an auxiliary medicine or for monotherapy with pathology of the digestive tract, small pelvis, bleeding gums, uterine bleeding, as well as skin diseases and upper respiratory tract inflammation.

Indications Kulgan

Thanks to anti-inflammatory, astringent, antibacterial and hemostatic properties, the drug is often used in gastroenterology. Indications for the use of Kalgan include its use in such pathological processes as increased gas formation in the intestine, bloating (flatulence), inflammatory process in the gastric mucosa and intestinal parts.

In addition, the drug is effective in the ulcerative lesions of the mucosa of the digestive tract, disruption of the intestine with the appearance of diarrhea of various causes, including in the presence of an infectious agent.

Indications for use of Kalgan also include bleeding from the pelvic organs and the digestive tract. The drug has a good effect on the inflammatory process in the bladder and urinary tract.

 For external use, Kalgan is used to stop bleeding gums and reduce their inflammation. The drug is effective in pharyngitis, tonsillitis and other inflammation of the larynx and tonsils.

In dermatology it is widely used in the form of lotions with frostbite, chronic wounds and burns. With hemorrhoids, Kalgan reduces the intensity of the inflammatory reaction and reduces swelling.

Release form

The main active substance is the roots of the Kalgan. The form of release is presented by the crushed kind of raw material and a large powder.

The physico-chemical properties of the crushed agent is a yellowish color with a red, brown tinge, up to a dark brown color. The rhizome is ground into pieces of various sizes, but not exceeding 7 mm in diameter.

The smell is almost invisible, but pleasant, the taste is highly astringent. The form of the release in the form of a powder is represented by pieces of the rhizome of the same color, but with the size of the pieces 4 times smaller (about 2 mm). Smell and taste similar to a coarse-grained agent.

In connection with the different form of release of the drug, it is necessary to distinguish the packaging of the medicine. So, the crushed 7 mm raw material is contained in one package, 50 g or 75 g, which is packed in a pack.

Finely divided rhizomes resembling a powder with a particle diameter of 2 mm are packaged according to filter packs of 3 g in an amount of 20 pieces in one package.

Pharmacodynamics

The plant belongs to a group of medicines that have their effect on the digestive system and metabolic processes. Due to its natural composition, in particular biologically active substances, the drugs have astringent, antibacterial, hemostatic and anti-inflammatory effects.

Pharmacodynamics Kalgan provides an anti-inflammatory effect by reducing the permeability of the walls of blood vessels and their narrowing. As a result, the liquid part of the blood lingers in the lumen of the vessel and does not enter the tissue. Thus, puffiness of surrounding tissues, intensity of hyperemia decreases and the severity of pain syndrome decreases.

With the help of Kalgan, the chances of coping with bleeding gums and an unpleasant odor from the oral cavity increase. By regular rinses and lotions, anti-inflammatory, antibacterial and hemostatic action is provided.

Pharmacodynamics Kalgan allows you to use the drug in inflammatory diseases of the larynx, in particular, angina. With the help of rinses, antiseptic and anti-inflammatory action is provided. 

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Pharmacokinetics

Kalgan is widely used in the pathology of the stomach and other organs of the digestive tract. Its beneficial effect is due to the presence in the drug of a tannin - catechin, which affects the muscle layer of the stomach, removing spasms and restoring physiological motility.

The pharmacokinetics of Kalgan is also carried out by glycosides, flavonoids, resins, cinchona and ellagic acids and essential oils. As for flobbaphene, it has an antibacterial effect that is used in all areas of medicine.

A whole complex of therapeutic effects of Kalgan is observed in action due to the presence of micro- and macro elements (zinc, copper, selenium), crystalline ether, tormentin and saponins, which are derivatives of α-amirin and tormentol.

Rhizomes are known for their vasoconstrictive, membrane-stabilizing effect, as well as normalizing the digestive process. 

Dosing and administration

Depending on the form of release and the composition of the drug, the method of administration and dose also vary. First, it is necessary to consider the use of large chopped rhizomes, which are stored in one package. They should be dosed alone with a measuring spoon.

To prepare the tincture, you need to pour 15 grams of crushed rhizomes into a glass of hot boiled water and cover tightly with a lid. Next half an hour you need to insist on a water bath, then filter and remove the present rhizomes.

The resulting broth should be brought to a volume of 200 ml with boiled water. Use should be for half an hour before a meal of 15 ml adults up to 5 times a day for a month.

The way of application and the dose of finely chopped rhizomes with a diameter of 2 mm is much simpler, since the medicinal product is already packaged in sachets of 3 g. So, 2 filter sachets should be lowered into a mug with boiling water (100 ml), cover and insist for about half an hour. Take should be the same as a large rhizome.

As for childhood, it is rational for them to use a decoction preparation for gargling with inflammation of the larynx and tonsils.

Use Kulgan during pregnancy

Pregnancy is a special period in the life of a woman, when it requires tremendous strength and health for the bearing of the fetus and its birth.

Throughout the period of pregnancy, an integral condition is the control over the medicines used and their health status as a whole. To this end, the woman regularly undergoes research, one of which is presented by ultrasound. It is necessary to observe the formation and development of the fetus.

Thus, the use of Kalgan during pregnancy is not allowed in view of the insufficient number of clinical studies and information on the effect of calgan on the fetus and the course of pregnancy.

Despite the fact that the medicine is a natural remedy, all the same, in order to avoid the negative impact of the constituent rhizomes on the fetus, its use is prohibited.

The same applies to the lactation period when the baby is breastfed. During this period, it is possible to get into his body substances that penetrate into the milk of the mother due to taking medications.

It has not been proven that Kalgan does not have the ability to enter breast milk, therefore, it should be discarded during the feeding period of the baby.

Contraindications

The drug, despite its origin (natural or pharmacological) can cause a response of the body, manifested by various clinical symptoms.

Contraindications to the use of Kalgan are presented by the peculiarities of the organism of each person. Genetically, information about the body's response from the immune system to certain substances can be transmitted.

Hypersensitivity to the components of kalgan can manifest itself as an allergic reaction of a local or general nature. In the case of taking the medicine inside increases the likelihood of developing hives or swelling of Quincke. The most dangerous is the swelling of the upper respiratory tract, which leads to asphyxiation.

In the case of using a medicament for rinsing throat or lotions, local reactions are most often observed. They are manifested in the form of hyperemia of the mucosa, its swelling and burning sensation.

Contraindications to the use of Kalgan also provide for the presence of constipation, since the medicinal components of the rhizome contribute to a decrease in the activity of peristaltic intestinal waves.

As for childhood, it is not recommended for babies to use the drug for oral administration. Only periodic rinsing of the throat is possible in order to reduce inflammation and death of microbes. 

Side effects Kulgan

In most cases, side effects of drugs begin to manifest themselves as a result of non-compliance with the recommendation for their use (dosage, frequency of use, the presence of concomitant pathology or joint use with other drugs).

Side effects of Kalgan can be manifested in the form of a hypersensitivity reaction. It is caused by the individual reaction of the body to taking the drug, which is transmitted genetically.

In the case of using a rinse aid in the form of a solution, the likelihood of irritation of the mucosa increases. Symptoms include redness, slight swelling and even rashes.

Side effects of Kalgan when using a drug orally can provoke nausea, vomiting and pain in the stomach and stomach.

In addition, allergic reactions to the use of the medication can be manifested by the sensation of itching, burning, tingling, swelling and hyperemia of the mucosa or skin.

When there are clinical symptoms of side effects, it is necessary to cancel the drug and then completely abandon its use or significantly reduce dosage.

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Overdose

Clinical symptoms of overdose are possible if the recommended dosages are not met, the frequency of use and the duration of the therapeutic course.

An overdose of the drug may occur after the first use, if the dose has been significantly exceeded or after several times of use, when the accumulation effect is observed.

When taking a large dose of Kalgan, you may experience a sharp pain in the stomach or abdomen. In addition, the general condition of a person worsens - there is dizziness, weakness, nausea and vomiting.

In some cases, cases of overdose with a violation of the intestinal function have been reported. In this case, a slowing of the peristaltic waves was observed, as a result of which constipation appeared.

There is no antidote of the drug, however, in case of overdose, it is necessary to cancel the further administration of the drug and try to remove as soon as possible its residues from the body. For this purpose, it is advisable to perform gastric lavage and forced diuresis in a hospital to reduce the residence time of the drug in the body.

Interactions with other drugs

Before using several drugs simultaneously, it is necessary to take into account their combined interaction with each other and the therapeutic effects that they can have for the body.

The interaction of Kalgan with other drugs is not fully understood, but it should be noted that the power of medication can be affected by food intake. In this regard, it is recommended to observe the interval between eating and using a medicine that is at least 30-40 minutes.

Since the drug affects the work of the stomach and other organs of the digestive tract, it is necessary to avoid joint intake with preparations of a similar mechanism of action.

The interaction of Kalgan with other drugs, the main pharmacological action of which is a hemostatic effect, it is worth considering their combined effect in order to avoid excessive activation of the coagulation system.

The drug is perfectly suited as an auxiliary component of treatment for cystitis, bleeding gums, sore throat, uterine bleeding and gastrointestinal pathology.

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Storage conditions

In order to preserve the necessary medicinal effects of the drug, it is necessary to take into account the peculiarities of its content So, each drug implies compliance with the conditions of its storage, which include maintaining the optimum temperature, humidity and light level.

Storage conditions Kalgan mean maintaining the temperature in the room where the storage of the drug is supposed to be no higher than 30 degrees. In addition, it is worth considering that it is inadmissible to hit direct sun rays on the drug.

If the storage condition of Kalgan is not observed, the preparation may lose its medicinal properties and have an adverse effect on the body. After preparing the broth from the rhizomes, it should be stored in the refrigerator.

In addition, the absence of access to the medicinal product of babies is considered a prerequisite. If they take a large amount of decoction inside, poisoning or overdosing is possible. In case of finding the crushed rhizomes, the guys can taste them, which also threatens their health.

Shelf life

The manufacturer of the drug must certainly indicate the date of manufacture of the drug and the last use. They are usually indicated on the outer packaging to facilitate access. Therefore, the expiry date should be checked.

During this period, the drug retains its medicinal properties, after which the use of the drug is prohibited.

The shelf life of Kalgan is 4 years, provided that the rhizomes are not used to prepare the broth. Once they have been welded, the maximum period of their application is no more than 2 days. In addition, it must be remembered that in the prepared form it is necessary to store the drug in the refrigerator.

In the absence of a refrigerator, storage of the preparation in the form of a decoction is allowed at a temperature of 2 to 8 degrees. Cold broth is not recommended.