Calendhoderm

Kalendoderm is a natural remedy, the main component of which is marigold extract. Thanks to its natural healing properties, the cream received a huge range of nutrients that help the person recover.

The main therapeutic effects characteristic of calendula are anti-inflammatory, antiseptic and analgesic effects. The medicinal preparation in the form of a cream is widely used in dermatology in order to activate the regenerative capabilities of the skin and accelerate the process of restoring their integrity.

The drug belongs to the pharmacological group, which includes homeopathic medicines. They are used with a therapeutic purpose for various diseases of the skin and its integrity as a result of the influence of a traumatic factor (temperature, sun, physical or chemical).

Kalendoderm is an effective remedy for wound healing, which has an anti-inflammatory and antiseptic effect. With their help, a rapid growth of new cells and a decrease in the wound surface are observed. 

Indications Calendhoderm

Based on the availability of medicinal properties in this medication, several groups of pathologies can be identified, the cause of which can be caused by various factors.

Thus, indications for the use of Kalendoderm are a disease of the skin with the formation of pustules. The therapeutic effect in this case is due to the antiseptic property of the drug. Thanks to the sanation of the focus, a decrease in the intensity of the inflammatory process and acceleration of the regeneration of skin cells are observed.

In addition, it is worth highlighting the effectiveness of the drug in relation to various damages to the integrity of the skin as a result of trauma or disruption of the local circulation (bedsores). Indications for use Calendoderm also include burn skin lesions (sunny, thermal), as well as frostbite.

Do not forget about the effect of the drug on the blood vessels. Thus, with varicose veins, there is a decrease in the manifestation of the vascular network due to an increase in the tone of the blood vessel and the narrowing of the vessels.

As a softener, Kalenderm is effective in the presence of rough skin on the heels and other areas of the sole. It is recommended to use the cream as lotions. During the whole course of applying the cream, the skin becomes softer and no "cracks" appear on the heels. 

Release form

Due to the fact that the drug is used to restore the skin, so the most effective effect in this case is the local application of the drug. The form of the release is represented by cream. Due to its consistency, the medicine is well applied to the damaged covers, completely covering them.

The main physicochemical properties are represented by a soft consistency, smooth to the touch - without lumps and grains. Light beige has a shiny color.

In terms of the main active substance, the cream contains 1 g of calendula (matrix tincture) per 10 g of the drug. Of the auxiliary components, it is necessary to isolate the preservative of benzyl alcohol, thick paraffin, purified water, cetyl alcohol, self-emulsifying ethylene glycol di- and monostearate, isopropyl myristate, octadecylheptanoate and octadecyl octanoate complex, and potassium hydroxide as a solution.

The cream well covers the skin, forming a protective layer. As the components of the drug penetrate the skin thickness, the pathological focus is sanitized and the inflammatory reaction gradually decreases.

Pharmacodynamics

Thanks to the plant composition, the pharmacodynamics of Calendoderma does not work very quickly, but it gradually achieves certain positive results.

When the drug is used, the pharmacodynamics of Calendoderm provide a reduction in the activity of the inflammatory reaction in the tissues, and also restores the structure of the damaged skin.

It should be noted the ability of the drug to stop small bleeding, reduce the intensity of the pain syndrome in fresh wounds or on the skin area with a chronic ulcer.

With the help of its ability to disinfect the wound, Kalendoderm is well suited for cleaning the lesion from purulent masses. The medicine effectively restores skin in case of burns, both sunny and thermal, and also with frostbite.

The consistency of the cream allows you to completely cover the required skin area. It is worth paying attention to the effect of the drug in the fight against dry skin, in particular when cracked rough skin on the heels.

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Pharmacokinetics

Influence on the inflammatory process is carried out by narrowing blood vessels, reducing the permeability of their walls, which in turn inhibits the release of the liquid part of the blood plasma from the lumen of the vessel into the tissue. Thus, the puffiness decreases.

In addition, there is a decrease in the pressure of edematous tissues on the nerve endings, thereby reducing the intensity of the pain syndrome. By blocking biological factors, the inflammatory focus becomes local and gradually narrows.

The pharmacokinetics of calendoderm are due to the ability of the drug to stimulate the growth and multiplication of cells, increasing the amount of granulation tissue. As it is formed, it is filled with defects in the skin.

As a result, the focus of the lesion is restored with a new tissue, which prevents the infection from getting into the deep layers of the skin. In addition, it should be noted that Kalendoderm is an antiseptic, which also helps the immunity of a person to cope with an infectious agent.

Purulent wounds are also sanitized by the preparation, which accelerates the process of formation of granulations and healing of the skin. This applies not only to wounds, the cause of which is a traumatic factor, but also formed as a result of insufficient local blood circulation.

Dosing and administration

Depending on the stage of skin lesions, prescription and depth, it is necessary to control the amount and frequency of use of the drug.

Most often, the drug is applied to the skin lesion site three times a day, but if necessary, it can be applied 4 times. Apply the cream should be a thin layer, covering the entire surface of the skin.

The method of administration and dose are selected individually for each case of disease or injury. So, to soften the coarsened skin on the foot, it is recommended to first make a foot bath in warm water, so that the skin becomes slightly softer. Then you need to apply the cream to the foot areas and, if desired, cover with a napkin. It is desirable to carry out this procedure several times a day, especially at bedtime.

With regard to the use of the drug on the wound surface, it is necessary to take into account the depth and area of tissue damage, since not always Kalendoderm can cope with pathology on its own.

Calendoderm can be used as an auxiliary preparation for the treatment of ulcers, burns and skin wounds. It is perfectly suitable for preventing infection of the wound surface. The cream can be used after washing the hearth with an antiseptic to protect against penetration of infectious agents. 

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Use Calendhoderm during pregnancy

Throughout the gestation period a woman should control the intake of medicines. The use of any pharmaceutical preparation must be preceded by a doctor's consultation. He should examine the woman and make a decision about his application.

The use of Calendoderm during pregnancy should also not take place without the supervision of a specialist in order to avoid a negative effect of the drug on the fetus. The use of a medicinal product is allowed only if the benefit to the pregnant woman is greater than the harm to the fetus.

Particular attention should be given to the period of the first three months, when the initial formation of organs and structures in the fetus occurs. At this time, any pathological factor, including the drug, is capable of provoking disorders and mutations in the fetus.

In the future, this threatens the inadequate functioning of internal organs or the lack of its working capacity.

In addition, it is worth noting the period after childbirth, when the baby is breastfed. There are no proofs of the penetration of medicinal components of the drug, but only Kalendoderm can be used by a doctor.

Contraindications

The main contraindication to the use of Calendoderm is the body's response to its use. These can be individual features of a person, genetically incorporated, or acquired properties of the immune system.

 Each preparation has in its composition the main active substances and auxiliary ones, therefore, the intolerance of the organism can manifest itself on any of the components.

Contraindications to the use of Kalendoderm include allergic manifestations when applying cream to the skin. So, in the case of a single or several applications of the cream, there is a hyperemia, greater in area than it was, an increase in swelling or pain, it is worth repealing its further use.

In addition, the reaction of the organism in the form of sensations of itching, burning or tingling in the place where the cream was applied is not excluded.

The general response of the whole organism to the use of the cream is unlikely, since only a small part falls into the common bloodstream, the dose of which is insufficient to develop a powerful allergic reaction.

Side effects Calendhoderm

Due to the natural composition of the drug, the frequency of adverse reactions is minimal, but nevertheless it is worth paying attention to the appearance of an allergic reaction in response to the use of the drug.

Side effects of Calendoderm may manifest in the form of clinical symptoms of allergies, such as increased intensity and area of hyperemia compared with the time before application of the drug. It is also possible to increase edema due to the release of mediators of inflammation in the lesion, the appearance of sensations of itching, tingling and even burning.

Side effects of Calendoderm may manifest itself after the first use of the drug, and after several days of use. Everything depends on the reactivity of the body's immune system and the individual tolerability of the components of the cream.

In the future Calendoderm is not recommended for use in order to avoid the development of a more powerful immune response and the appearance of other adverse reactions of the drug.

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Overdose

Overdose symptoms are usually observed as a result of not following recommendations on the use of the drug in certain dosages and multiplicity. Thus, the accumulation of active substances and increased side effects.

Overdose Kalendoderm is almost impossible, since penetration into the common bloodstream is so insignificant that it can not cause deterioration of a person's condition after repeated use.

In rare cases, local clinical symptoms of overdose are possible, although they hardly differ from the manifestations of side effects from the use of the cream.

When applying the cream in a thin layer and gently rubbing, the active components of the drug penetrate into deeply lying layers of skin and begin to perform their therapeutic function. After a few hours (up to 6 hours), almost no cream remains in the wound area, which requires repeated application. As a consequence, there is no accumulation of the drug and the development of an overdose.

Interactions with other drugs

When using any medication, you should know its interaction with other drugs that are taken simultaneously with it.

So, Kalendoderm's interaction with other drugs has not been fully revealed, but it should be noted that only a small part of the main drug component can penetrate into the common bloodstream. In this regard, as a whole, there can not be a bright pharmacokinetic and pharmacodynamic conflict.

Calendoderm may locally stimulate the therapeutic effect of other creams and ointments, but in order to avoid the summation of their side effects, it is still not recommended to apply the cream earlier than 4-6 hours after using another ointment.

If several creams of different medicinal groups are intended, then it is first necessary to familiarize yourself with the effect of each preparation separately and to calculate the time interval between them, which must be observed.

During this period, the absorption of the main components of the drug occurs, and therefore their combined interaction can not be fully manifested.

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Storage conditions

In order to maintain the necessary medicinal ability of the drug over a long period of time, it is necessary to take into account the peculiarities of its storage.

So, Kalendoderm storage conditions mean maintaining a certain temperature regime, humidity level and illumination. For the purpose of long storage, the optimum temperature is up to 25 degrees. In addition, direct sunlight should not fall on the package with cream.

Storage conditions Calendoderm should be observed throughout the expiration date in order that all the medicinal properties of the drug indicated in the instructions are preserved. In addition, if the recommendations are not observed, Calendoderm may have a negative effect on the body, causing a lot of adverse reactions.

A prerequisite is the lack of access of children to the drug. The baby can taste the cream, which will lead to poisoning. In addition, there is no known reaction to the use of the drug in childhood.

Shelf life

For a certain period of time Kalendoderm retains its healing properties, which are checked by the manufacturer before the release of the drug. Validity period Kalendoderm is 5 years, but it should be taken into account that this applies only to the cream that has not been opened.

If Kalendoderm has already been used, then the maximum period, during which it is permitted to use it, is only 6 months. After expiration date the drug can not be used.

The expiry date refers to those medicines that were stored under certain conditions, without violations. When sunlight gets on the cream or when the temperature rises above 25 degrees, the likelihood of losing the medicinal properties of the drug increases. In this case, it can have a negative impact on Kalendoderm.