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Health

Alluna

, medical expert
Last reviewed: 10.08.2022
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Alluna is a hypnotic sedative medicine. The calming effect of medications containing hop cones and valerian roots has been confirmed and empirically recognized after preclinical and clinical testing.

To date, no clinical trials have been performed on hop cone extracts as an insomnia reliever. But at the same time, at least 4 randomized tests were conducted (prospective comparatively controlled or placebo) with fixed combinations of valerian root and hop cones, along with 45% methanol (w / w) dry extracts. [1]

Indications Alluna

It is used to treat several sleep disorders, including insomnia , trouble falling asleep, and restless sleep.

Release form

The release of the drug substance is made in tablets - 10 pieces inside the cell pack; inside the box - 1 or 3 such packs.

Pharmacodynamics

After ingestion of the fixed combinations of the above extracts in the recommended portions, an improvement in the course of the latent phase of sleep, as well as its quality, was noted. Such an impact is unlikely to be associated with any known elements.

Several principles of the therapeutic effect of different elements of the valerian root (lignin and sesquiterpenoids with flavonoids) have been registered, which possibly demonstrate clinical activity and interact with the GABA system, as well as cause agonism with respect to the A-1 adenosine endings and synthesis with the 5-HT 1A end. In addition, several mechanisms of activity of different elements of hop cones (flavonoids with bitter acids), as well as agonism in relation to melatonin terminals (ML1 with ML2), interaction with GABA and synthesis with subtypes of serotonin terminals (5-HT4e, as well as 5-HT6 with 5-HT7). [2]

There is currently no information available on hop cone extract - whether it acts on its own as a mild sedative or synergistic with valerian root extract.

Dosing and administration

The medication is taken orally - 1 tablet, 1 hour before bedtime. You need to swallow the medicine with plain water. If required, the serving can be increased to 1.5 tablets.

The gradual transition of the therapeutic effect of Alluna does not allow the use of a fixed combination of hop cones and valerian root for acute interventional therapy of sleep disorders or mild forms of nervous stress. To restore stable sleep, the herbal preparation must be taken for at least 14 days. To obtain the optimal effect of therapy, it is necessary to continue the course for 1 month.

If the signs of the disease persist or their deterioration after 1 month of constant use of drugs, consultation with a doctor is required.

  • Application for children

You can not use the medicine in pediatrics.

Use Alluna during pregnancy

There is no information regarding the safety of using Alluna in hepatitis B and pregnancy. It is forbidden to prescribe medication during the indicated periods.

Contraindications

The main contraindications:

  • severe intolerance to the active or auxiliary components of the medication;
  • depression and other conditions in which there is a suppression of the activity of the central nervous system.

Side effects Alluna

Among the side symptoms:

  • disorders of the gastrointestinal tract: it is possible to develop problems with the functioning of the gastrointestinal tract, including diarrhea, nausea, abdominal cramps and vomiting;
  • lesions of subcutaneous tissues and epidermis: epidermal signs appear singly;
  • disorders associated with the work of the PNS and CNS: drowsiness, depression, dizziness, systemic weakness, suppression of emotional manifestations and weakening of physical and intellectual capacity for work;
  • immune problems: symptoms of intolerance, including itching, skin swelling, rashes and hyperemia.

Overdose

A dosage of valerian root in the amount of about 20 g leads to the appearance of mild disorders (abdominal cramps, dizziness, severe fatigue, mydriasis, a feeling of compression in the sternum and tremors of the hands), which disappear after 24 hours.

There is only limited information regarding intoxication with a fixed combination of valerian root with hop cones. Sometimes, after using 25 tablets of the drug per day, drowsiness, dizziness, atypical sounds in the peritoneal region, anxiety and tachycardia were noted.

With the repeated development of the above-described manifestations, supportive procedures should be carried out.

Interactions with other drugs

When a medication is combined with artificial sedatives, constant medical supervision is required.

Valerian substances are able to potentiate the effect of sedatives, analgesics and hypnotics, alcohol, anxiolytics and antispasmodics.

Storage conditions

Alluna should be kept in a dark and dry place, out of the reach of small children. Temperature values - no more than 25 ° С.

Shelf life

Alluna can be used for a 36-month term from the date of manufacture of the medicinal substance.

Analogs

The analogues of the drug are medicines Valdispert, Noxon with Valerian tincture and Sonafit.

Attention!

To simplify the perception of information, this instruction for use of the drug "Alluna" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.

Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.

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