Instillagel

Instillagel shows a local anesthetic and disinfecting effect. The drug has a combined composition - its components are the substances lidocaine and chlorhexidine.

Chlorhexidine has an impact on gram-negative and positive microbes, yeast, treponema with dermatophytes, ureaplasm, chlamydia and trichomonads. Continues to operate actively and in the presence of discharge, pus and blood.

Lidocaine has a local anesthetic effect.

[1], [2],

Indications Instillagel

It is used for the following violations and procedures:

• catheterization in the urethra;
• cystoscopy or urethroscopy;
• operations in the area of the bladder and prostate;
• therapy with cystalgia or urethritis;
• vaginal reorganization before childbirth;
• hysteroscopy;
• curettage procedure for diagnosis;
• endometrial biopsy;
• polypectomy in the uterine cervix;
• therapy for colpitis with cervicitis or endometritis;
• conducting proctological operations;
• endoscopic examinations in children.

Release form

The release of the drug component is implemented in the form of a gel, inside a 1-time plastic syringe with a volume of 6 and 11 ml.

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Pharmacodynamics

Thanks to the transparent gel, you can get a high-quality optical overview, which is why it is often used when performing endoscopy.

Antimicrobial effect and anesthesia manifest themselves after 5-10 minutes from the moment of using the drug.

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Dosing and administration

Each syringe can only be used once.

In the case of urological pathologies, it is required to apply a little substance in the area of the urethra, and then place the cannula inside its opening, then inject 11 ml of substance (in men). During cystoscopy, treatment with the whole urethra is required (11 ml of gel is applied, as well as another 6 ml, if required). Syringes with a capacity of 6 ml are injected into children and women. During a variety of endoscopic procedures after applying the gel, you must wait about 10 minutes to get an analgesic effect.

When performing gynecological procedures, you must use 6-11 ml of the drug. First you need to cover the area of the external pharynx with the preparation, and then move the tip of the syringe to the area of the cervical canal and uterine cavity.

If you need to use Instillagel during lactation, you need to stop breastfeeding for 12 hours from the moment of the introduction of the drug.

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Use Instillagel during pregnancy

It is necessary to appoint very carefully in the 1st trimester.

[5], [6], [7]

Contraindications

The main contraindications:

• severe intolerance to parabens;
• bradycardia, which is pronounced (because there is a likelihood of suppression of the heart).

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Side effects Instillagel

Among the side effects: rash, dermatitis, having an allergic nature, angioedema, and burning in the treatment area.

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Overdose

Gel overdose can occur in case of severe damage to the urethra - this leads to the simplification of the absorption of lidocaine with its subsequent systemic influence, manifested in the form of seizures, bradycardia and collapse. Incorrect use of drugs can cause orthostatic collapse.

In the case of bradycardia, it is necessary to use β-adrenergic stimulants, and during convulsions - muscle relaxants with a short-lasting type of influence or barbiturates; dopamine is administered intravenously during collapse.

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Interactions with other drugs

It is forbidden to combine medication with iodine medication.

Instillagel is not compatible with detergents containing sodium lauryl sulfate and saponins, as well as with soap.

MAOIs are able to potentiate the drug activity of lidocaine.

[18], [19]

Storage conditions

Instillagel must be maintained at a temperature not exceeding 25 ° C.

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Shelf life

Instillagel can be used within a 5-year term from the time the therapeutic substance is produced.

Analogs

Analogues of the drug are gels Lidochlor and Katedzhel (containing lidocaine), as well as spray Lidocaine Acept.

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Reviews

Instillagel is often used in a variety of diseases. In the reviews, his high drug activity and good tolerance are noted. For children, this medicine allows local anesthesia for any type of endoscopy (colonoscopy or esophagoduodenoscopy). The gel improves the sliding of the applied tool and quickly anesthetizes the treated areas.

Comments also reported that the drug is used in combination therapy for premature ejaculation.

[22], [23]