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Insana
Last reviewed: 23.04.2024
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Insuman is a hypoglycemic drug, is a subgroup of insulins and their analogues with an average duration of the drug effect.
The drug helps to fill the deficit of internal insulin, which occurs in the case of the development of diabetes mellitus, and at the same time reduces blood sugar levels. The drug is a substance identical to human insulin, and in addition it has an average duration of therapeutic effect.
Indications Insana
It is used in the case of diabetes mellitus, having an insulin-dependent nature. Due to the delayed development of therapeutic effects and a rather long-lasting effect, the drug is used during long-term therapy, especially in the case of a stable form of diabetes with a low insulin need.
Release form
The release of the medicament is realized in the form of an injectable suspension, inside the bottles with a capacity of 5 or 10 ml; In the box - 5 such flakonchikov. In addition, the substance is produced in the form of a suspension to accommodate OptiPen - inside 3 ml cartridges, 5 pieces inside a pack.
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Dosing and administration
The medication is applied s / c method, 45-60 minutes before eating food. The area of injections must be constantly changed. Portion size is selected individually for each patient.
Adults who first use the drug, you need to start with the introduction of the dosage of 8-24 IU 1 time per day.
Children and adults who are hypersensitive to insulin may suffice and servings less than 8 units per day. Persons with reduced insulin requirements may require a dosage of more than 24 U per day.
Once allowed to enter no more than 40-ka substance. Exceed this portion is allowed only in extreme cases.
If insulin is replaced with animal-like insulin, you may need to reduce the amount of insulin.
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Use Insana during pregnancy
Clinical information regarding the use of human insulin substances during pregnancy is not available. Insulin is not able to overcome the placenta, but the drug in the specified period is still prescribed very carefully.
Patients who develop diabetes before conception or during pregnancy (gestational pathology), it is extremely important to closely monitor the metabolism of carbohydrates throughout the entire gestation period. Insulin need may be attenuated in the 1st trimester and increase in the 2nd and 3rd. After delivery, the insulin requirement decreases sharply, which increases the likelihood of hypoglycemia. Therefore, it is very important to closely monitor the indicators of glucose.
Insuman has no effect on nursing infants who are breastfed by women using the medicine. The use of drugs during lactation is allowed, but may require adjustment of its portions, as well as diet.
Side effects Insana
Side effects include lipodystrophy, signs of allergy in the form of itching, epidermal rashes and urticaria, as well as insulin resistance. In case of severe renal impairment or alcohol use, hyperglycemic manifestations may occur.
Overdose
When insulin poisoning can develop severe and sometimes prolonged hypoglycemia that threatens the patient's life.
At light stages of hypoglycemia, correction can be made simply by ingesting carbohydrates. In addition, you may need to change the dosage of the drug and nutritional regime or regime of physical activity.
If hypoglycemia has severe severity, and neurological disorders and a coma are observed against its background, a glucagon or concentrated glucose fluids are required. Prolonged introduction of carbohydrates and patient monitoring should be made mandatory, because the attacks of hypoglycemia may have relapses after the patient's condition improves.
Interactions with other drugs
The use of many medications can affect the metabolic processes of glucose, which may require a change in the dosage of human insulin.
Among the drugs that can potentiate the antidiabetic effect and increase the propensity to develop hypoglycemia include ingested hypoglycemic drugs, fibrates, pentoxifylline with an ACE inhibitor, propoxyphene, fluoxetine with disopyramide, salicylates, MAOI, and sulfonamides.
Substances that can weaken hypoglycemic activity are danazol, glucagon, GH, GCS, thyroid hormones, diazoxide, progestins with estrogens (for example, OK), diuretic drugs, sympathomimetics (for example, terbutaline and adrenaline with salbutamol), agents that slow down protease, as well as isoniazid with phenothiazine derivatives and atypical antipsychotics (clozapine with olanzapine is among those).
Clonidine, alcoholic beverages, β-blockers and lithium salts can both weaken and potentiate the hypoglycemic effect of insulin.
The use of pentamidine can provoke hypoglycemia with the further development of hyperglycemia.
At the same time, under the influence of individual sympatholytics (guanethidine and clonidine with reserpine) and β-blockers, the symptoms of adrenergic counterregulation can be reduced or completely disappear.
Storage conditions
Insuman is required to be kept in a dark place at temperatures in the range of 2-8 ° C. It is forbidden to freeze the medicine.
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Shelf life
Insuman can be applied within a 24-month term from the date of manufacture of the therapeutic element.
A used pen (or carried with you as a spare) can be stored for a maximum of 1 month at temperatures of no more than 25 ° C (it must be kept away from direct sunlight and heat sources).
Application for children
The required experience of using the drug in pediatrics is missing.
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Analogs
Analogs of drugs are the substances Actrafan NM, Semilente, Ultralente, Isofaninsulin NM and Protophan with Iletin, and in addition Homofan 100, Insulin-b, Humulin ultralente with Inuzofan, Homolong 40 and Lente with Ultardard NM, and Monotard.
Attention!
To simplify the perception of information, this instruction for use of the drug "Insana" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.