Coprinol from alcoholism

This drug for the treatment of alcohol dependence is produced in Russia by Bionika. Producers present their offspring as a bioactive vitamin supplement, which generates a strong aversion to alcohol consumption, restores liver function and enhances the immune barrier.

Koprinol has not passed the procedure of official registration as a bioactive additive, it can not be purchased in the pharmacy chain or store. Distributed through the Internet and distributors. Although some sources claim that it can already be bought at the pharmacy.

This drug works even without the knowledge of the patient, which is convenient for his relatives, trying to eradicate this addiction. However, such a method is not welcomed by doctors, since the use of alcohol during treatment can lead to serious consequences that threaten the health and life of the patient.

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Indications of the coprinola

The drug, ideally, is indicated for the treatment of chronic alcoholics who are not at the stage of drinking-bout, and consciously wanting to get rid of addiction. Also, it can be taken for preventive purposes in the early stages of alcoholism.

Release form

Oral suspension, packaged in vials of polymer material or glass ampoules. Presented in a variety of containers from a daily dose of 2ml to 60ml in a single vial or ampoule.

The names in use are used differently, if we are talking about drops or a solution of Koprinol, then this is the same.

Pharmacodynamics

The main active ingredient that causes the necessary aversion to alcoholic drinks is the extract of the fungus coprinus or white manure. The aversive effect of this fungus, related to conditionally edible, in combination with alcohol was noticed long ago, this remedy is used by alternative healers for the treatment of alcoholism. Disulfiram contained in the coprinus, reacting with ethanol causes acute intoxication accompanied by severe nausea and vomiting, fever, headache and heart pain, tachycardia and other severe symptoms of this condition.

Disulfiram-ethanol reaction is the inhibition of the enzymatic activity of acetaldehyde dehydrogenase, which catalyzes the metabolism of ethyl alcohol, at the stage of the formation of the toxic substance of acetaldehyde, and the delay of its further cleavage into acetic acid and water safely leaving the body. This leads to the accumulation of acetaldehyde in the body, and the appearance of symptoms of acute poisoning, causing the patient's suffering, right up to the fear of death. Usually this state lasts no more than two hours. As a result, the conditioned reflex of the connection of drinking with symptoms of poisoning is formed, after several repetitions, the patient begins to abandon alcoholic beverages, not wanting to survive the attack of intoxication again. It is this property of the koprinus that makes it possible to develop a persistent reflex to alcohol in the patient even without his knowledge.

Succinic acid  is a good anti-smoker, normalizes cellular respiration, liver and kidney function. Along with polyunsaturated fatty acids, vitamins and minerals, it helps to increase the body's defenses, increase metabolism and other functions that are disturbed in the process of chronic alcoholism.

Pharmacokinetics

The multicomponent bioactive additive does not apply to medicines, therefore the data are not presented.

Dosing and administration

The drug is tasteless and does not smell, so it is recommended to add it to meals or drinks once a day in a dose not exceeding two milliliters. The greatest effectiveness from the application should be when adding it to milk and dairy products. Do not exceed the recommended dose.

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Use of the coprinola during pregnancy

It is forbidden to use pregnant and lactating women.

Contraindications

It is not recommended to use Koprinol for persons who have not reached adulthood, and also for patients older than 60 years, since in old age the probability of a lethal outcome increases during an attack of acute intoxication. The drug should not be given to alcoholics in the drinking-bout period. It is contraindicated for allergies to contained components.

Decompensated chronic diseases of the cardiovascular, endocrine system, gastrointestinal tract (ulcers, hemorrhages), respiratory organs, liver and kidneys are also contraindications to use.

It is not recommended to treat patients with active tuberculosis, neoplasms, inflammation of the visual and auditory nerve, neuropsychiatric pathologies, including alcoholic genesis.

Side effects of the coprinola

Development of acute respiratory, hepatic and cardiac insufficiency, circulatory disorders of cerebral vessels, coma, collapse, convulsions, inflammation of the liver, jaundice, acute psychosis.

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Overdose

Exceeding the permissible dose is fraught with depression of the function of breathing, heart, brain, up to the development of collapse and death.

Interactions with other drugs

Not represented.

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Storage conditions

Store no more than 18 months, observing the temperature regime up to 25 ℃, avoiding heating and direct sunlight. Keep away from children.