Venter

Venter has antiulcer effect.

Indications Ventera

It is used in such cases:

• treatment and prevention of exacerbations of gastric or intestinal ulcers;
• Hyperphosphatemia in people with uremia who are on hemodialysis;
• prevention of stress caused by ulcers;
• therapy for reflux esophagitis.

Release form

The release of drug substance is realized in tablet form, in the amount of 10 pieces inside the blister plate, 5 or 10 plates inside the box.

In addition, the preparation is made in granules, inside bags of 2 g, in the amount of 50 pieces inside the box.

Wenter-new

Venter-Nova is produced in tablet form, 12 pieces each inside a blister pack. The package contains 2 such packages.

Pharmacodynamics

The active ingredient of the medicament is the sucralfate-disaccharide element, which contains sucrose sulphate together with aluminum hydroxide. The use of the drug helps the rapid healing of peptic ulcer lesions, prevents the appearance of gastrointestinal ulcers, and also helps protect gastric mucosa from the negative effect of hydrochloric acid and pepsin. Due to the use of Venter, the activity of pepsin decreases by 30%. In this case, the drug does not have a significant effect on the pH of the gastric juice.

The therapeutic effect is based on the synthesis of sucralfate with proteins located inside the diseased tissues of the mucous membranes, thus creating a protective film over the ulcer surface. The medication increases the rate of scarring of existing ulcers and healing of lesions, and besides it prevents the recurrence of pathology and the appearance of stress caused ulcers. Along with this, there is a decrease in phosphate absorption in the gastrointestinal tract.

Pharmacokinetics

After oral administration, the active element is slightly absorbed into the circulatory system. The medicine does not form clinically significant plasma indices and does not have a systemic effect. Metabolism is also not affected by the drug component.

Partial excretion of drugs occurs through the kidneys, and the remainder is excreted through the intestine, in an unmodified state.

[1]

Dosing and administration

Use tablets or granules of the drug Venter should be taken orally. Tablets must be swallowed whole by washing them with plain water. If the patient has difficulty with swallowing the medicine, the tablet may be dissolved in water, which must then be drunk. Granules are also designed for use after dissolving in normal water.

The prepared solution from granules is required to be consumed before meals (0.5-1 hour). The length of the treatment cycle is selected by a doctor who takes into account the severity of the disorder and the individual characteristics of the patient.

An adult should take 2 tablets or 2 bags of LS granules a day. In this case, this dosage is divided into 2 uses - in the afternoon, before dinner, and then in the evening, before going to bed.

When a patient is diagnosed with hyperphosphataemia, a reduction in portion is required. With a peptic ulcer, it is allowed to increase the daily dosage by half. The treatment cycle for people with a peptic form of the gastrointestinal ulcer lasts approximately 3 months. Until then, the use of the drug can not be canceled, even if the signs of the disease disappear. It is recommended to continue therapy before the diagnosis, which will confirm that the ulcers began to cicatrize.

To prevent the development of ulcers caused by stress, an adult is prescribed the use of the 1st pill or sachet, 6 times a day.

To prevent recurrence of ulcers, you need to take twice a day for the first pill or a packet of medicines. For a day allowed to take a maximum of 8 tablets / sachets. People with problems in the work of the kidney need to shorten the treatment cycle.

Children over 4 years of age should take 0.5-1-well tablets of the drug, a maximum of 4-fold per day. To assign Venter to children in granules is forbidden.

[2], [3], [4]

Use Ventera during pregnancy

Pregnant or lactating women, Venter is appointed with caution.

Contraindications

The main contraindications:

• disorders in the work of the kidneys, having a pronounced character;
• presence of strong sensitivity with respect to medicinal elements.

With care, the medication is prescribed for people with kidney deficiency that has a chronic form.

Side effects Ventera

Taking medication can provoke such negative symptoms: nausea, dry mouth mucosa, gastralgia, vomiting, constipation, bloating and diarrhea. In addition, insomnia, pain in the lumbar region, a feeling of drowsiness, dizziness, allergy symptoms and headaches may appear.

Overdose

The drug is often transferred without complications, so the probability of developing intoxication is minimal.

But using drugs in excessively large portions can lead to the appearance of symptoms of hypersensitivity or allergic symptoms. Among the manifestations of abdominal pain, vomiting, rash or irritation on the epidermis, as well as nausea. When these disorders occur, you need to perform symptomatic procedures.

People with kidney failure after prolonged therapy may experience poisoning, which develops into osteomalacia or encephalopathy. In such cases it is necessary immediately to stop the treatment, perform the procedures of peritoneal dialysis, hemofiltration and hemodialysis, and in addition introduce deferoxamine.

Interactions with other drugs

When combining the drug with antacids, you need to keep an interval between their use, which is at least half an hour.

With simultaneous use with Venter, the absorption of cimetidine, digoxin, tetracyclines with ranitidine is weakened, and in addition ciprofloxacin, ofloxacin with norfloxacin and indirect anticoagulants, as well as theophylline. Therefore, with such combinations it is required to adhere to the interval between uses, which is at least 2 hours.

Combination of the drug with phenytoin weakens the absorption of the latter and reduces its concentration, at which the resumption of seizures is observed. Because of this, it is also recommended to observe 2-hour intervals between the use of drugs.

[5], [6], [7], [8]

Storage conditions

Venter should be kept in a place protected from moisture and penetration of children. Temperature indicators are standard for medicines.

[9]

Shelf life

Venter can be used within 3 years of the release of the therapeutic agent.

[10]

Application for children

Children under the age of 4 years are prohibited from using the drug.

Analogues

Analogues of the drug are drugs Ankrusal, Sukrat and Alsukral with Ulgastran and Sukralfat. In addition, Maalox, Rennie and De-Nol, with Almagel, have a similar effect.

Reviews

Venter is often discussed in various medical forums, because many people have various problems with digestive activity. Sometimes they have a slight degree of severity - for example, failures in the nutritional process or overeating; and at times there are quite serious diseases, such as gastritis or peptic ulcer. Therefore, medicines intended for the treatment of digestive and digestive diseases are of great demand in patients.

It is reported that the drug has different effects on different people and does not always help to eliminate problems with the function of the gastrointestinal tract. However, in the same reports it is mentioned that these commentators started using the medicine on the recommendation of other people, without preliminary examination and appointment of a doctor. They usually turn to a specialist only after the appearance of severe pains, and on the examination they are diagnosed with a serious illness, in which they in their reviews accuse the pills that did not have the desired result, although the problem was the lack of a correct diagnosis and selected therapy. Because of this, it is recommended not to engage in self-medication, leading the situation to serious complications, and immediately go to a doctor who can choose a suitable medicine for the patient.

[11], [12], [13]