Ultop

Ultop is a drug that inhibits secretory actions for the release of gastric juice. This drug does not affect histamine receptors and does not have an active effect on the nervous system. The active substance in this drug is omeprazole. Due to the fact that this connection is formed, activity decreases, and accordingly, increased secretion of gastric juice is inhibited.

Indications Ultop

The drug can be prescribed to those patients who undergo therapy against various diseases of the gastrointestinal tract. In case of Ultop prescription, the symptoms are reduced in a short time. The mucous membrane of the organ heals in a fairly short time - within four weeks.

Ultop may be prescribed to those who have duodenal ulcers or benign ulcers in the body that occur as a result of taking non-steroidal drugs.

Indications for use apply to those patients who need to relieve symptoms of dyspepsia and take preventive measures to normalize the acidic environment of the stomach.

Ultop for gastritis

Some patients who are prescribed the Medication for gastritis may be alarmed by the fact that this medicine is antiulcer. But Ultop is prescribed for gastritis because the medicine primarily affects the level of acidity and its suppression in the stomach. The Medication is also used for various diseases that are associated with surges in the level of acid in the stomach.

Release form

The medication is available in the following forms:

• The tablets, containing ten mg of the drug, have a hard gelatin shell and are available in two colours – white and pink.
• The pills, which contain twenty mg of the drug, have a hard gelatin shell, the body is colored pinkish. The cap is brownish or pinkish.
• The pills, which contain forty mg of the drug, are a hard gelatin shell, the body is colored pink-brown. The cap is light pink.
• Pills containing ten and forty mg contain white and yellowish or pinkish pellets inside.
• Pills containing twenty mg are white pellets.

Pharmacodynamics

Pharmacodynamics - this is a drug belonging to a group that suppresses active secretion of gastric juice, but does not have an anticholinergic effect. Omeprazole has a suppressive effect on the activity of the proton pump. The drug reduces the amount of stimulated secretion. The effect of omeprazole depends on the amount and frequency of the dose taken. The proton pump begins to reduce its activity within sixty minutes and the achievement of the maximum therapeutic activity of omeprazole occurs in two hours. After a single dose, the effect lasts for six days. In case of repeated administration, the effect increases during the first four days, and then a constant level of action occurs. After the end of the course, acid secretion returns to normal in three days. The bioavailability of the drug, in case of a single dose, reaches forty percent and increases further.

Pharmacokinetics

After the drug has been taken orally, it is quickly absorbed from the gastrointestinal tract into the blood plasma, the action of the pharmacokinetics of the drug occurs within one hour. The drug undergoes quite active metabolism processes in the liver. The drug is excreted through urine - seventy-five percent, the remaining twenty-five - through bile and feces.

In case of kidney disease, the excretion of metabolites may decrease; the same processes are possible in elderly people.

Dosing and administration

Ultop is used internally, orally, and must be washed down with plenty of water.

For gastric ulcers, the usual dose is twenty mg twice a day. The course lasts from two to six weeks.

For ulcerative lesions of the duodenum - one capsule twice a day for four weeks.

For gastroesophageal reflux disease - one capsule twice a day, the course lasts up to eight weeks.

For maintenance therapy – one capsule once a day for a year.

For chronic gastritis, when an increased level of acid is formed in the stomach, the method of application and dosage are calculated for a three-week course - one capsule of twenty mg twice a day.

Use Ultop during pregnancy

There are currently no clinical studies that prove the neutral effect of the drug on the fetus during pregnancy. However, the drug can be used to treat pregnant women under strict supervision of the attending physician together with the gynecologist - after all possible risks and consequences of use during pregnancy have been assessed.

During lactation, it is necessary to stop breastfeeding until complete recovery.

Contraindications

Contraindications for use apply to the following groups of patients:

• Patients under eighteen years of age;
• Pregnant women and women who are lactating or breastfeeding;
• Have a hereditary form of fructose intolerance;
• There is a syndrome of glucose-galactose indigestion;
• There is a deficiency of sucrose in the body;
• An increased reaction to one or more components of the drug is possible.

It is necessary to consult a doctor and weigh all possible negative effects before taking Ultop for those who have chronic kidney or liver diseases.

Side effects Ultop

When taking the drug, the following side effects may occur:

• Digestive system – severe diarrhea, prolonged nausea accompanied by vomiting, local abdominal pain, constipation, impaired taste perception, impaired appetite, changes in stool color.
• Central nervous system – prolonged headaches and dizziness, attacks of aggression, apathy or nervousness, some excitement, possible drowsiness, insomnia.
• Vessels – angina pectoris, various edemas, changes in blood pressure.
• Urogenital system – various urinary tract infections.
• Muscle weakness and bone pain, in rare cases - cramps.
• Leukocytosis and thrombocytopenia may develop in the blood.
• Itching, rashes, and, in extreme and rare cases, hair loss may occur on the skin.
• Cough reflex, sore throat, nosebleed.
• Various hearing or vision impairments
• Hypoglycemia.

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Overdose

When taking this medicine during the day in the amount of 360 milligrams - overdose is not observed. If the permissible dose is exceeded, there may be an increase in drowsiness, dizziness or headaches, abdominal pain, dry mouth, impaired coordination, blurred vision, increased sweating. In rare cases, shortness of breath or hypothermia occurs.

When treating the consequences of an overdose of Ultop, it is necessary to engage in therapy to eliminate the symptoms. But remember that hemodialysis will not be able to cleanse the body.

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Interactions with other drugs

When taken together with caffeine, diclofenac, metoprolol, theophylline, ethanol, lidocaine, estradiol, no changes in the blood were detected. When taken together with antacids and Ultop, the active components also do not interact with each other. A decrease in the absorption of ampicillin or iron salts is possible.

Clarithromycin enhances the absorption of Ultop into the blood.

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Storage conditions

The storage conditions for the medicine should include a dry place that is protected from direct sunlight and other sources of light falling on the packaging. The temperature of the room in which the medicine is stored should not exceed 25 °C – normal room temperature.

The location you choose for storage should be securely protected from children and pets.

Violation of the storage conditions for Ultop leads to a reduction in the shelf life of the drug.

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Special instructions

Analogues

Currently, pharmacies and pharmaceutical companies offer the following analogues of Ultop: OMEZ, Chrismel, Helicid, Zhelkizol, Ortanol, Zorsel, Romesek, Omepruz, Zerocid, Nolpaza, Vero - Omeprazole, Omizak, Demeprazole, Zerocid, Losek, Omecaps, Ulzol, Helicid, Omefez, Tsisagast, Gastrozol.

Ultop or Omez

For those who do not know how to decide between such drugs as Ultop or Omez, first of all, it is worth paying attention to the list of side effects and the country of manufacture. It is in these two points that the difference lies. After all, both drugs have one active substance - omeprazole. The drug Ultop is Slovenian-made and undergoes more degrees of purification, accordingly, it has fewer side effects, unlike Omez, which is produced in India.

Nolpaza or Ultop

Nolpaza is a medicinal analogue of the drug Ultop, as it also has the active substance omeprazole. The choice depends on the characteristics of your disease and the individual characteristics of the body. The attending physician will determine which drug is best for you - Nolpaza or Ultop.

Ultop or Nexium

In case of choosing between Ultop or Nexium - it is necessary to consult with your therapist. Regardless of the fact that both drugs contain the active substance omeprazole - it is necessary to know the characteristics of the body and possible susceptibility to the components.

Pariet or Ultop

Your attending physician may prescribe you either Pariet or Ultop when treating acid balance. There is no reliable clinical data that Pariet is more effective than Ultop. The only difference is that Pariet appeared on the market somewhat later and is a drug of new developments.

Reviews

Reviews of the drug among patients are mostly positive. The affordable price of the tablets, fast and effective impact on the acid level in the stomach add positive qualities, and, consequently, reviews. Buyers may be scared off by a large number of possible side effects, but it is worth remembering that side effects do not occur in every patient.

Manufacturer

The manufacturer is Slovenia. The drug has been on the domestic market for a long time and enjoys well-deserved popularity. The main activity of the Slovenian pharmaceutical company is the development of high-quality drugs of its own brand, which will be an additional value for consumers. The manufacturer of Ultop made sure that the drug underwent the necessary purification from harmful impurities.

Shelf life

If all storage conditions are met, the medicine does not lose its therapeutic properties. But if the temperature at which the medicine was stored was exceeded for a long time, high humidity was maintained in the room or the seal of the package was broken, the shelf life of the medicine is reduced. Always check Ultop before starting to take it.
The shelf life is two years from the date of manufacture.