Ultravist

Ultravist is a diagnostic tool that is used for computed tomography, spinal cord and brain research, urography, arthrography, diagnosis of various endocrine system diseases, nervous system, respiratory system, gastrointestinal tract disorders, musculoskeletal system, circulatory system, genitourinary system , as well as for the diagnosis of formations, including malignant ones. It is a transparent liquid that does not have foreign particles in its composition. The main active ingredient is iopromide. This is the radiocontrast fluid, which is used for intravenous administration, intra-arterial administration, and also into the cerebrospinal fluid. The drug Ultravist is transferred quite well, but nevertheless, side effects are possible and there are a number of contraindications to the use. The dose is picked up by a specialist during the preparation for the study. It depends on the patient's weight, age, type of diagnosis and other specific indications for use by Ultravist. Below you can find full information on the use of pharmaconometics, pharmacodynamics, various forms of release, special instructions for use during pregnancy and the period of breastfeeding, the impact on the elderly, children of different age groups, as well as analogues in the pharmaceutical market. Produces Ultavist, the German pharmaceutical company Bayer Schering Pharma, which is located in Berlin. Value for money and quality at a high level.  

Indications Ultravist

Ultravist is used only for research and is not a therapeutic tool shown for the treatment of a number of diseases. With the help of it, all parts of the body are diagnosed. It is administered intravenously, intraarterially, and also an injection into the spinal cord. Depending on the dose and indications, the diagnostic specialist selects the type of study. It can be a computer tomography, spinal cord research, arthrography, urography and other kinds, in which a contrast liquid is used. Different forms of release make it possible to economically use this drug in accordance with the necessary dosages and the duration of treatment. 

Release form

The ultravist has a different form of release. It is available in the form of vials of different dosage and volumes. Dosage is in accordance with the amount of active substance - iopromide, ie 240 mg, 300 mg and 370 mg. The volume can be 10 ml in a vial, 20 ml in a vial, 50 ml in a vial and 100 ml in a vial, 200 ml in a vial and 500 ml in a vial. The variety of forms of release allows you to choose the best option for a specific case of diagnosis and medical research. A suitable option is suggested by the specialist during preparation.

[1]

Pharmacodynamics

The pharmacodynamics of the ultravist effect on the human body is very simple. After the introduction of a liquid from the active substance into the interior, it increases the contrast during diagnostic studies using ray methods such as computed tomography, spinal cord studies, arthrography, urography, and others. The minimum pharmacological activity characterizes Ultavist with binding to proteins in the blood slightly. The effect on the kidneys and the cardiovascular system is very small.

[2]

Pharmacokinetics

Pharmacokinetics Ultravist includes the absorption of active substances, their distribution in the body, metabolic processes and the last stage of excretion. After intravenous or intra-arterial administration of the drug, it is quickly distributed in the body, after 1-5 minutes you can already carry out medical research. One third of the active substances can be detected in the blood plasma three minutes after application. In clinically acceptable doses of the drug, the metabolite was not detected. There is no such thing as a metabolism. If the patient's kidneys function normally, then there should be no problems with excretion. In the event that this function is violated, the specialists will pay special attention to this issue. Usually, after 2 hours, iopromide is half removed from the body.

[3], [4], [5]

Dosing and administration

Regarding the way of application and doses, there is a huge variety. The ultravist is administered intravenously, intraarterially, and also injected directly into the spinal cord, more precisely, the fluid through the membranes of the brain. The drug should be heated to the temperature of the body, the person who will be tested. The solution of Ultavist must be used once and immediately after opening the vial. The dose is calculated according to the body mass of the patient, age, general condition of the body, method of medical research, paying special attention to risk groups and possible contraindications to use.

[11]

Use Ultravist during pregnancy

Use of Ultravist during pregnancy is contraindicated, since the safety of the use of this drug is not established. If nevertheless there is an acute need to take the drug, then it is worth consulting with the attending physician about the Ultravist analogues and the advisability of using it during pregnancy. Do not forget about the same risks that can lie in wait for mom and future baby. How will the drug affect the development of the baby in the womb and after birth? If the need to appoint during the period of breastfeeding, then apply this drug. The active ingredient is partially excreted in breast milk. According to modern observations, this does not harm babies.

Contraindications

Contraindications to use Ultravist should be carefully studied before use. There are no categorical contraindications, but it is very carefully used for diabetes, renal and hepatic insufficiency, in case of repeated use or a significant increase in the dose of Ultravist. Do not forget about the possible hypersensitivity to active components, take into account the age of the patient, because older people are more difficult to tolerate the introduction of contrast media for examinations. During pregnancy, use the drug is contraindicated. If there is a need for it, it is worth assessing the harm and benefits of the examination for mom and future baby.

[6], [7]

Side effects Ultravist

When the Ultravist is injected into the vessels, there are usually no side effects or they are carried in mild form. Different sensations are possible, such as: nausea, dizziness, drowsiness, vomiting, allergic reactions (rashes on the body, itching of the skin, urticaria), changes in body temperature (increase or decrease). But do not negligently treat negative feelings and symptoms because there are also severe forms of side effects of Ultravist, which can lead to serious complications and even death. But do not be afraid of research and possible reactions, because the feeling of fear enhances and increases the likelihood of side effects.

[8], [9], [10],

Overdose

Long-term studies of the Ultravist, which were carried out on animals, did not show special severe forms of overdose and intoxication of the organism as a whole. There may be unpleasant sensations on the part of the cardiovascular system, lungs. To do this, it is necessary to monitor the work of the kidneys, and the removal of fluid from the body. Hemodialysis will be effective, since the contrast fluid is excreted perfectly from the body. In the future, supervision over the patient's condition should be anticipated for the next three days. Possible difficulty breathing, seizures, inhibition and other side effects from the central nervous system.

[12], [13], [14]

Interactions with other drugs

There are certain indications on the interaction of Ultravist with other drugs. This way of taking drugs to study the function of the thyroid gland is not recommended. Since the testimony may not be believable. After the administration of the drug, Ultravist should pass from 10 days, and preferably two weeks. If the patient is using certain antidepressants, then a reduction in the threshold of seizures is possible. This increases the risk of reactions that are associated with the use of contrast fluid. When taking immunomodulating drugs, belated reactions are possible. It's a fever, a chill, a feeling of the initial stage of the flu.

[15], [16]

Storage conditions

The storage conditions of Ultravist are very simple. It should be in a dry, dark place at a temperature of no higher than 30 ° C. Children should not have access to a medicine. The shelf life is not more than 3 years for vials. An open vial should be used at the same time, not stored in a refrigerator or other place. Active components lose their healing qualities. Ultravist should not be used after the expiration date. A streaked preparation may have a completely different effect on the course of the study. Before use, carefully read the date of manufacture and instructions for use.

[17], [18]

Special instructions

Analogues Ultravist

In case they could not find Ultravist in pharmacies, there is an analogue. This drug is called Yopromide. It is produced by LLC "Fermex-Group". This company is located in the Kiev region and is one of the most modernly equipped manufacturing companies in the CIS, on its base there is a huge research base. If compared with other post-Soviet producers, this complex is equipped, in accordance with the requirements of the latest European standards in the pharmaceutical industry. Therefore, you should not worry about quality. Replace the drug only a specialist who will conduct the study.

[19], [20], [21], [22], [23],

Shelf life

Shelf life Ultravista is 3 years, provided that the rules of storage, temperature, lighting and other necessary parameters are observed. After the expiration of three years, use the drug is strictly prohibited. Therefore, it is worthwhile to carefully look at the date of manufacture of this drug when buying at a pharmacy, and especially if it has been lying in the medicine cabinet for a long time. Do not forget that a drug that is already overdue does not retain its medicinal qualities. 

[24]