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Ugrin
Last reviewed: 03.07.2025
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Ugrin is an antiseptic dermatological agent that is classified as an antimicrobial drug of plant origin.
Indications Ugrin
The following indications for the use of Ugrin are distinguished:
- acne, inflammation of the sebaceous glands;
- seborrheic skin lesions of the face of varying severity or its prevention;
- purulent inflammatory skin diseases ( pyoderma );
- inflammatory processes on the skin ( dermatitis );
- facial skin hygiene.
Ugrin is also indicated for daily care of oily and problematic skin, especially in adolescent patients.
In addition, the aseptic properties of Ugrin allow it to be used as a means of reducing the oiliness of facial skin and for preventive care of normal skin prone to inflammation, blockage of the sebaceous glands and various rashes of bacterial etiology.
Release form
Ugrin is an alcohol tincture that is produced in dark glass jars of 100 ml. Each jar is sealed in a cardboard package.
The tincture consists of a number of herbal ingredients, supplemented with 40% ethyl alcohol.
The preparation contains:
- yarrow raw material 15 mg;
- mint leaves 15 mg;
- chamomile flower 20 mg;
- celandine raw material 1 g;
- lavender raw material 1 g;
- calendula flower 15 mg;
- tansy flower 1.5 g.
Tincture Ugrin is a dark brown liquid with a characteristic aroma.
Pharmacodynamics
Ugrin is an external medicine consisting of herbal ingredients. Ugrin tincture has a significant antimicrobial, anti-inflammatory and restorative effect, while it does not have a damaging effect on nearby healthy tissues. During the use of the medicine, there is no overdrying of the skin, redness, itching.
However, the mechanism of the therapeutic effect of this herbal preparation can be briefly described, since it is based on the combined action of the substances of medicinal plants included in its composition: chamomile, yarrow, calendula, tansy, peppermint, lavender and celandine.
Azulene and salicylic acid of chamomile, chamazulene of yarrow, phytoncides and succinic acid of celandine are known for their antibacterial and anti-inflammatory effects. Turpentines, flavonoids and organic carboxylic acids of calendula and tansy have bacteriostatic activity. The coumarin metabolite umbelliferone, contained in lavender, disrupts the integrity of the outer cell membrane of such gram-negative and gram-positive bacteria as Streptococcus epidermidis, Streptococcus pyogenes, Streptococcus aureus, Propionibacterium acnes, Clostridium perfringes, Candida albicans, etc.
Chlorogenic acid compounds, which are present in significant quantities in mint leaves, reduce the activity of cellular enzymes that provide the synthesis of structural elements of many bacterial strains. Zinc compounds, which are abundant in the listed plants, have an antiseptic, astringent and drying effect.
The mechanism of action of Ugrin gel, which is produced on the basis of Ugrin tincture, is enhanced by the introduction of the antiseptic chlorhexidine (active against gram-positive and gram-negative bacteria Treponema pallidum, Chlamydia spp., Ureaplasma spp., Neisseria gonorrhoeae, Gardnerella vaginalis and the herpes virus) into the composition of the drug, as well as the preservative antiseptics nipagin and nipazole.
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Pharmacokinetics
The pharmacokinetics of Ugrin have not been fully studied. It is known that the drug is well accepted by tissues, has a positive effect on the condition of the skin, and does not contribute to moisture loss by the skin.
In most cases, the effect of Ugrin occurs after 3-5 days of treatment.
Dosing and administration
Ugrin is used strictly externally. It is not recommended to dilute or mix the preparation with any other product.
This medicine is applied to a cotton pad and the affected and problem areas of the skin are gently wiped. After applying the product, do not rinse your face with water or use other lotions, liquids or cosmetics for 2 hours.
If there are acne lesions on the surface of the skin, you should not open or squeeze them.
To enhance the effectiveness of the treatment, patients are recommended to wash their faces with contrasting water in the morning and evening using baby soap. The duration of therapy with the drug and the frequency of its application should be determined by the doctor on an individual basis.
As a rule, patients with acne and seborrhea are prescribed Ugrin up to 5 times a day.
The duration of the procedures is from 3-4 days to 2 weeks. If necessary, repeated therapy can be prescribed 2 weeks after the end of the last course.
In case of inflammatory processes in the skin, the medicine is used for at least 1 month, about 4 times a day. An additional therapeutic course may be prescribed.
For preventive purposes to maintain healthy facial skin, Ugrin is used daily 1-2 times a day.
Use Ugrin during pregnancy
The use of Ugrin during pregnancy or breastfeeding is not encouraged, since there is currently no reliable information that this medication is safe for the unborn child and does not affect the course of pregnancy.
The question of using the drug Ugrin by pregnant women must be discussed with a doctor.
Contraindications
Contraindications to the use of Ugrin are:
- tendency to allergy to any of the components of the drug;
- childhood (up to 12 years);
- pregnancy and breastfeeding (studies of the drug's effects during pregnancy have not been conducted).
If you doubt the possibility of using the drug for one reason or another, you should consult with your doctor.
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Side effects Ugrin
Overdose
Cases of overdose with Ugrin have not been described.
If the drug is accidentally taken orally, signs of alcohol intoxication may develop, as well as dyspeptic symptoms (nausea, vomiting, diarrhea, abdominal pain).
Storage conditions
It is recommended to store the medicine Ugrin in dry conditions, out of direct sunlight, at standard room temperature (range 15-30°C). Children should not be allowed near places where medicines are stored!
Shelf life
The shelf life of the medicine Ugrin is up to 2 years, if the proper conditions are met. If the expiration date indicated on the package has expired, or if visible sediment or turbidity has appeared in the medicine, it is recommended to throw the medicine away.
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Attention!
To simplify the perception of information, this instruction for use of the drug "Ugrin" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.