Tigeron

Infectious diseases can catch a person at any time. They are caused by various microorganisms. To combat the negative impact of infection on the body was called the drug Tigeron. It helps to overcome many problems, including relapses. 

Indications Tigeron

The remedy is widely used to eliminate infectious diseases of various origins. The main indication for the use of Tigeron is the control of microorganisms sensitive to the action of levofloxacin. This list includes negative processes that occur in the upper respiratory tract. It can be both pneumonia and bronchitis.

Tigeron is designed to fight and with infectious lesions of the genitourinary system. This includes chronic prostatitis, uncomplicated pyelonephritis, urethritis and cystitis. This tool can be used alone or in complex therapy. In addition, the medication removes infectious diseases that affect the skin and soft tissues. It can be septicemia, bacteremia and even intra-abdominal infections.

The remedy is very strong, therefore it is not recommended to apply it alone, there is a risk of harming your own organism. 

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Release form

Tigeron is available in the form of tablets. They differ only in the content of the active component in them. So, the form of the release of the drug is a tablet of 500 or 750 mg. All of them are covered with a special coating, which facilitates swallowing. Not all people are able to swallow tablets without problems. Manufacturers of this tool took this moment into account. In one blister is 5 tablets, in the package can be up to 2 blisters.

In addition to the tablets, the product is also available as a solution for infusion. In one glass vial is 100 ml of the drug. There is one bottle in the carton. There are no other forms of packaging. In which form to use Tigeron decides the attending physician depending on the condition of the patient, as well as the degree of development in him of a particular disease. Independently to resort to the choice of Tigeron is not worth it, in order to avoid exacerbating the situation. 

Pharmacodynamics

The main substance that is part of Tigeron is levofloxacin. This component is classified as an antibiotic, which has a broad spectrum of action. Levofloxacin is an antibiotic of the third generation of the fluoroquinolones group. Antimicrobial activity is enhanced by the molecules of levofloxacin and fluorine. Bactericidal effect is achieved by influencing the synthesis of DNA, this is the basis of pharmacodynamics.

The active component is able to block enzymatic topoisomerases, including DNA hydrazide. They, in turn, act as catalysts in the process of spiral-despiralization of DNA. It is the one that is most necessary when performing normal DNA replication.

Due to the inhibition function of intracellular enzymes, irreversible processes in the cells of the microorganism can occur. In the end, this leads to his death. Tigeron has an effective effect against infectious diseases. Including those that were caused by gram-positive and gram-negative microorganisms. It should be noted that the agent does not have a bactericidal action against spirochaetes. 

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Pharmacokinetics

When administered orally, Tigeron is well absorbed in the intestine. Moreover, it has remarkable bioavailability. As for the pharmacokinetics, it does not change depending on the mode of administration. It should be noted that the use of food can lead to inhibition of absorption of levofloxacin. But this does not lead to a process of reducing plasma concentrations of the agent.

The maximum amount in the blood plasma is reached after an hour after ingestion. If the agent is used at a dosage of about 1000 mg per day, it is possible that the active ingredient will accumulate in the body. Uniform plasma concentrations are achieved after three days. About 40% of the drug binds to plasma proteins.

The drug is able to penetrate most tissues, as well as biological fluids in the body. It is able to create therapeutically significant concentrations in affected areas. In this case, we are talking about the tissues of the upper and lower respiratory tract. The agent is not able to penetrate the blood-brain barrier. A small part of Tigeron is able to be metabolized by means of dimethylation. The period of excretion of Tigeron from the body is 8 hours. Excretion is performed mainly by the kidneys, practically unchanged. The other part comes in the form of metabolites. 

Dosing and administration

The agent should be used no more than 2 times a day. Everything depends on the prescribed dosage, which the doctor will recommend. If a twice-prescribed drug is prescribed, it is necessary to do this at regular intervals. As for the method of application and the dose of Tigeron, it all depends on the severity of the disease, as well as the characteristics of the patient's body. Usually, the duration of treatment is not two weeks.

The solution must be administered intravenously drip. As for the duration of the infusion, it should not be less than an hour for every 100 ml of the solution. In the acute course of the disease, it is necessary to combine the infusion with the administration of tablets. In the presence of simple infections, it is necessary to use 250 mg of the drug no more than once a day. In this case, the duration of treatment is 3 days.

If the infection is complicated, the dose remains the same, but the duration of the intake is increased to 1-2 weeks. With prostatitis, you need to take 500 mg of the drug throughout the month. If the functionality of the kidneys is impaired, 20-50 ml per minute is enough, it all depends on the severity of the course of the disease. The exact dosage for each disease is individually prescribed by the doctor. If the patient normally functions liver and kidneys, then the dose adjustment is not provided. 

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Use Tigeron during pregnancy

During pregnancy, you should refuse to take the medicine. The fact is that it is a broad spectrum antibiotic. In the period of bearing a baby such influence on the body can lead to the development of serious pathological processes. Therefore, the use of Tigeron during pregnancy is prohibited.

A similar requirement applies to the period of breastfeeding. It is necessary to exclude taking Tigeron or on the contrary to stop feeding the baby with breast milk. This is something that, in no case, can be used in the period of bearing a child. In this case, the term does not matter. Antibiotics are under strict prohibition. Naturally, the special risk remains for the first time weeks after conception. This period is dangerous for the possibility of miscarriage or development of a pathological process in a child. In any case, the use of the drug should be controlled by a doctor. Tigeron is used only if the positive result for the mother is much higher than the possible deviations in the child. 

Contraindications

Tigeron can not be used when hypersensitivity to its main component. This can cause serious allergic reactions from the body. The main contraindication to use is epilepsy. The presence of a propensity to convulsive seizures does not provide for the use of this drug. Such an influence can aggravate the situation.

Naturally, the medicine should not be taken during pregnancy. An antibiotic can harm a child's body, so its use before the age of 3 years is prohibited. With caution the agent is used by patients who have cerebral circulation disorders. Includes anamnesis.

Finally, the tool should not be used by people whose work requires increased concentration of attention. Tigeron inhibits mental activity, and dissipates a person's consciousness. Therefore, the management of dangerous mechanisms and the use of the drug are not combined in any way. 

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Side effects Tigeron

The drug belongs to the group of antibiotics, so it can lead to the development of serious adverse reactions. The gastrointestinal tract can react inadequately to such an invasion of the body. As a result, nausea, anorexia, vomiting and indigestion develop. But this is not all the side effects that Tigeron causes. In rare cases, it promotes the development of colitis, as well as reducing blood sugar levels, as well as increased irritability. Very rarely increases the activity of liver enzymes. As a result, hepatitis can develop.

The central nervous system is also capable of reacting negatively. Perhaps the development of headaches, increased fatigue, sleep disturbances. In some cases, patients develop anxiety, tremors and convulsions. Very rarely taste changes, olfaction worsens, and vision and hearing are impaired.

The cardiovascular system can respond with the development of arrhythmia, tachycardia and increased blood pressure. Very rarely there is neutropenia, possibly the appearance of thrombocytopenia, as well as agranulocytosis. In isolated cases, the appearance of collapse and pancytopenia was recorded.

On the part of the musculoskeletal system, the appearance of pain in the muscles and joints, as well as a decrease in their elasticity. Patients can complain about the presence of muscle weakness, as well as rhabdomyolysis. From the side of the genitourinary system, jade and acute renal failure are not excluded.

Finally, allergic reactions may occur. These include: skin rash, hives and itching. Perhaps the development of edema Quincke, bronchospasm, as well as anaphylactic shock. Other adverse reactions include general weakness and fever. 

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Overdose

If a person takes the drug in too high a dosage, development of serious reactions on the part of the organs and systems of the organism is not ruled out. So, first of all start to pester the symptoms of an overdose. They are characterized by the appearance of nausea, vomiting, dizziness. Sometimes a person observes a violation of coordination of movement, he has convulsions.

In this case, you need to know what to do. When there is a strange symptomatology, the first thing is to wash the stomach with a lot of liquid. This will remove excessive amounts of the drug from the body and alleviate the condition of a person. There is no specific antidote for this drug. It is necessary to wash the stomach and resort to the help of antacid preparations. It is advisable to monitor the patient's condition until all the symptoms of an overdose disappear. You can wash your stomach yourself, then you should call an ambulance or tell your doctor about the situation. 

Interactions with other drugs

With the simultaneous use of this drug with magnesium and aluminum, it is possible to reduce intestinal absorption. If there is an urgent need to use these medications together, you should observe the interval between doses. It is desirable that it was not less than 2 hours. When interacting with other drugs, in particular Sucralfate, it is possible to lower the bioavailability of Tigeron.

Simultaneous use of the drug together with non-steroidal anti-inflammatory drugs can lead to a decrease in the convulsive threshold. It is not ruled out that side effects of medicines are increasing. Tigeron is not recommended for use with Fenbuffen, this leads to an increased concentration of levofloxacin.

Probenicid and cimetidine can reduce the rate of excretion of the drug. If it is used concomitantly with Cyclosporin, an increase in the half-life period is possible. If it is necessary to simultaneously use Tigeron and vitamin K antagonists, it is necessary to monitor the clotting factor. After all, in this case, the risk of bleeding increases. 

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Storage conditions

The product should be stored in a dry place, away from direct sunlight. This will avoid premature spoilage of the drug. It is important to observe the storage conditions, especially the temperature regime. It should not exceed 25 degrees of heat. Otherwise, the product can quickly become unusable.

Dampness prevents the normal storage of medicines. Therefore, it is desirable to choose a warm and dry place. Soaking blisters leads to spoilage of tablets, this condition must be observed without fail. Direct sunlight also adversely affects Tigeron. Excessive exposure can lead to Tigeron's damage. Optimal storage conditions are: compliance with temperature, humidity and dryness. In this case, Tigeron will last a long time.

Shelf life

You can keep Tigeron for 2 years. During this period it is necessary to observe special storage conditions. Only they are the guarantor of the safety of the drug. In fact, the expiration date is just a figure.

In order for the product to last long, it is necessary to provide it with normal conditions. The first thing to pay attention to is the temperature regime. Thus, the optimal storage temperature should not exceed 25 degrees of heat. But this is not enough, it is important that Tigeron is not affected by direct sunlight. To do this, it must be stored in a dry and dark place. Moisture is the enemy of any medicine. It can lead to blistering and blistering of the drug. Therefore, this condition must also be followed.

If the color of the tablets, smell or consistency has changed, then the storage conditions were not met correctly. It is necessary to get rid of the drug, it is not recommended to use it. A similar requirement is made in the case of expiration of the expiration date.