Pharmacological action of the most common sorbent, such as activated carbon, is based on the porous structure of this substance, which absorbs and binds foreign particles (including toxins) that are in the stomach and small intestine.
Enterosorbiruyuschee White coal (which refers to dietary supplements, and not to pharmacological preparations) combines in its composition silica (silicon dioxide) and MCC. Silicon dioxide has long been used as an additive of E551, which prevents the formation of lumps in food, and microcrystalline cellulose (MCC) is a hydrophilic food supplement E460. So there is no coal in the composition of this additive, and what is called aerosil in advertising is silicon dioxide, only very crushed. By the way, it is used as a thickener and stabilizer in many industries. It is a good sorbent, and, if it gets into the gastrointestinal tract, it binds foreign and toxic particles in biological fluids (by attracting molecules with polar functional groups), which are then removed from the body.
In the descriptions of White Coal tablets there is no information on microcellulose, which in virtually every tablet is almost the same (208 mg) as silica (210 mg). MCC is a hydrophilic fibrous substance (obtained from cotton fluff) that does not undergo digestion and, when it enters the stomach, absorbs water and swells (while absorbing everything there is in the gastrointestinal tract). Also, it is not explained how both components interact with each other.
But the intestinal adsorbent Polyphepan contains finely divided organic non-carbohydrate fibers of wood - hydrolytic lignin, which does not dissolve in water and does not decompose under the action of intestinal enzymes. Lignin acts similarly to activated carbon.
In addition to hydrolytic lignin, the tablets against swelling and constipation of Lactofiltrum contain an osmotic laxative in the form of a synthetic stereoisomer of lactose (milk sugar), lactulose. The relaxing effect of lactulose is due to the fact that in the intestine it is not absorbed, due to which there is an increase in the osmotic pressure at which water passes into the lumen of the colon, increasing the volume of feces and diluting them. In addition, the intestinal microbiota is normalized, since obligate microorganisms, absorbing lactulose, contribute to the creation of an acidic environment - unfavorable for the decay and growth of opportunistic bacteria.
Used in diarrhea and dysbiosis of the intestine, Linex (in capsules) refers to eubiotics and has in its composition lyophilizylates of live lacto- and bifidobacteria that make up the intestinal microflora. Useful microorganisms in the intestine begin to function, contributing not only to its full-fledged work, but also to the suppression of the activity of pathogenic microbes.
Therapeutic effects capsules Espumizan provided simethicone -kremniyorganicheskim polymer with high surface activity. By reducing the surface tension of gas bubbles, simethicone promotes their rupture and free exit of intestinal gases without bloating.
The pharmacodynamics of the combined preparation Gaspospase is based on the same simethicone, as well as on the antispasmodic dicyclovirin hydrochloride, which removes muscular spasms of the intestine by blocking M-cholinergic receptors.
Pancreatin (Creon, Mezim-forte, Mikrazim, etc.) replenishes the body with pancreatic enzymes - pancreatin, lipase, amylase and protease, which leads to a significant improvement in digestive functions and a more complete assimilation of the body's essential nutrients.