Syrup Erispirus from cough for children

Cough syrup for children is prescribed for children with various types of cough: with a dry, moist cough, with cough of allergic and asthmatic origin, against inflammatory and infectious diseases.

Syrup Erispirus from cough for children is a syrup that comes in the form of a liquid that has a bright red, orange tinge. The drug has a pleasant smell of cherries, so it's easy to get a child to drink such a syrup. The active substance is fenspiride hydrochloride. As auxiliary components, sucrose, glycerol. This information can be important for children with impaired carbohydrate metabolism and increased sensitization of the body. It should be taken into account that the active ingredient is potassium sorbate, cherry flavor, dyes, which can cause allergic reactions. Especially dangerous are these components to those who suffer allergic reactions of immediate type, such as Quincke's edema, a tendency to anaphylaxis.

Indications Syrup Erispirus

Tonsillitis, sinusitis, bronchitis, pneumonia, pleurisy, diphtheria, acute respiratory disease are diseases in which this syrup ideally fits. Often used as an aid to relieve cough attacks against the background of the asthmatic component. It can be used as a maintenance therapy in the treatment of infectious diseases such as measles, diphtheria, whooping cough, various viral diseases of the respiratory tract, including influenza, ARI. Can be used as a means of providing supportive therapy.

For more information on syrups used for cough for children, see  this article.

Pharmacodynamics

In the study of pharmacological properties, it was established that the syrup refers to bronchodilator and anti-inflammatory components. The effect is that the drug helps reduce bronchopulmonary spasm, eliminates the inflammatory and infectious process in the airways. The basis of this mechanism of action is antagonistic activity, which manifests itself in relation to histamine receptors.

Also a distinctive feature is the myotropic spasmolytic activity of the musculature. By stimulating the release of biologically active components, the tone of the bronchi increases significantly. It is worth noting an interesting fact: the essence of the action is to stimulate the receptors of the mucous membranes. Their activation contributes to the fact that the secretion of active substances increases. Then comes the subsequent increase in activity of the mucous membranes, increases their propensity to self-repair, increase resistance and the ability to withstand infection and inflammatory processes.

It should be noted that the drug also has immunostimulating properties: it stimulates the activity of ciliated epithelium, goblet cells of mucous membranes, resulting in the body becoming more enduring, has the ability to withstand the inflammatory and infectious process, prevents its progression. Also significantly increases the tone of the bronchi, which contributes to the fact that the sputum becomes more mobile, much faster is eliminated from the body. Accordingly, the healing process is much faster, relapses do not occur. A positive effect is also a decrease in the number of free radicals.

Pharmacokinetics

When studying the pharmacokinetic properties of the body, it was established that the preparation possesses a high absorption capacity. Within 12 hours, the concentration begins to gradually decrease, and after 12 hours, completely reduced by 3 times. Removal of the drug from the blood occurs due to the kidneys. With the help of the intestine, about 10% of the drug is eliminated. The half-life is 12 hours.

Dosing and administration

It is recommended to prescribe the drug at a rate of 4 mg per kilogram. 

Contraindications

There are some contraindications to the use of this medication. For example, it can not be taken with hypersensitivity to fenspiride. It is best not to give the syrup to children under 2 years old. Treatment is often combined with antibiotic therapy, then the effect of the syrup is enhanced, and the effectiveness of antibiotics also significantly increases.

Side effects Syrup Erispirus

When taking the drug, it is necessary to observe that there are no side effects: complicated rhinopharyngitis, trachea, tracheobronchitis. Sometimes you can have attacks of suffocating cough: during the night sleep, early in the morning. Sputum usually with difficulty leaves, which leads to the development of stagnant phenomena, the prolongation of the inflammatory process.

Also, there may be various negative reactions from the respiratory and digestive system, in particular, suffocation, digestive disorders. There is irritability, a breakdown. Tachycardia and high blood pressure can develop.