Suppositories from gardnerellez and ureaplasmosis

Suppositories from gardnerella and ureaplasma help normalize the microflora of the vagina and be cured of certain types of bacteria.

Indications for use

These drugs are used to treat two separate female diseases:

1. Bacterial vaginosis, which is also known as gardnerellez.
2. Ureaplasmosis.

Ureaplasmosis is caused by a bacterium ureaplasma. Thanks to the use of suppositories, this disease can be effectively treated on an outpatient basis without the need for hospitalization. At the heart of such drugs are various antibiotics.

Before using suppositories, always consult a doctor.

First, such drugs are not suitable for everyone.

Secondly, they can be needed only in advanced cases of ureaplasma.

Thirdly, the specialist will recommend a complex therapy that will help to get rid of ureaplasmosis completely.

Gardnerella is a dysbacteriosis of the vagina. This disease is considered quite common, but not serious. In this case, the number of lactobacilli necessary for the female body decreases, and pathogenic microbes (gardnerella) begin to multiply instead.

Effective in treating gardnerellez are various candles, which can only appoint a professional.

Pharmacodynamics and pharmacokinetics

Consider pharmacodynamics on the example of popular suppositories from gardnerella and ureaplasma "Terzhinan".

It is a combination drug that is actively used in modern gynecology. It differs in antimicrobial, antiprotozoal and anti-inflammatory action. Thanks to this tool, you can achieve the integrity of the mucous membrane of the vagina and the consistency of its pH.

The composition of the drug includes three main active ingredients: ternidazole, neomycin and nystatin. Also in it is prednisolone. Ternidazole acts on fungi fungicidal, reducing the synthesis of ergosterol in membranes, shows high activity against gardnerell.

Neomycin is a broad-spectrum antibiotic. Struggles with gram-positive and gram-negative microorganisms. Nystatin is considered a popular antifungal drug, which acts mainly on fungi of the genus Candida.

Studies of the pharmacokinetics of the popular drug from gardnerella and ureaplasma "Terzhinan" have not been carried out, since it is characterized by a rather low level of systemic absorption.

The names of suppositories from Gardnerella

First of all, it is necessary to pay attention that the treatment of gardnerella is carried out in two stages. At what, the second stage without the first will not be effective at all.

First, the doctor prescribes a suppository with antiseptic and antibacterial action, which eliminate the causative agent of the disease. Then the vagina is "populated" by a normal microflora with the help of suppositories with live lactobacilli.

The most common suppositories from Gardnerella are:

• Macmirror. Active active substance of the drug is nifuratel (derivative of nitrofuran).

It differs anti-protozoal, antimicrobial, antifungal effect. In bacterial vaginosis, one suppository is used three times a day. The therapy lasts a week. The main contraindications to the use of the drug are: pregnancy, intolerance of components. Side effects are rare: allergies, nausea, headache.

• Terzhinan. Active active substances of the drug are - neomycin sulfate, nystanine and ternidazole. Thanks to this, the suppository has an antifungal effect. With gardnerellami fights just nistan.

To treat gardnerellez "Terzhinan" is administered once a day (preferably in the evening, since after the administration of the drug, the woman needs to lie down). Therapy lasts ten days. The drug is contraindicated during pregnancy and with intolerance of its main components. Side effects are: itching, burning in the vagina, an allergy.

• The Metrovit. Active active ingredient of the drug is metronidazole, which effectively fights gardnerella.

It is used once a day (preferably at night) at a dosage of 500 ml of the drug (1 suppository). The duration of therapy is determined by the doctor. Do not take with: blood diseases, organic lesions of the central nervous system, pregnancy, liver disorders. Among the main side effects are the following: vomiting, eating disorders, unpleasant aftertaste, headaches, poor sleep, allergies, leukopenia, burning in the urethra, irritability.

For the second stage of therapy usually use:

• Lactonorm. Vaginal capsules based on live lactobacilli, which help to completely restore the vaginal microflora after gardnerellez. One suppository is used twice a day. The course of therapy lasts from seven to fourteen days.

• Atzilact. Vaginal suppositories, which are based on the living mass of acidophilic lactobacilli. To improve the microflora of the vagina, the drug is used from five to ten days. One suppository is administered per day.

Dalacin

Active active ingredient of the drug is clindamycin. It is a semisynthetic antibiotic-lincosamide. Is active in relation to some gram-negative bacteria (including gardnerella).

Dosage is prescribed by a doctor. To avoid complications, it is necessary to strictly adhere to his recommendations. Usually, adults administer one suppository three to four times a day. The duration of therapy is two weeks.

The main side effects of using Dalacin are: nausea, which is often accompanied by abdominal pain and vomiting, jaundice, stomach ulcer, allergic reactions (rash, itching, redness, urticaria), leukopenia, thrombocytopenia, vaginitis.

The drug is contraindicated for use in: gastrointestinal diseases, myasthenia gravis, chronic liver diseases, pregnancy, lactation, intolerance of components.

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Method of application of suppositories from gardnerella

The dosage of the drug depends on the disease and the individual characteristics of each patient. Usually, one suppository is administered per day. As a rule, this is done in the evening, before the woman goes to sleep, since after the introduction of the drug, it is necessary to lie down for at least 15 minutes.

The course of therapy depends on which particular agent you use. In some cases, it lasts only a week, sometimes it takes from ten to fourteen days.

Use of suppositories from gardnerella during pregnancy

Gardnerellez during pregnancy to date is found in 20% of cases. This disease is quite serious for a future mother, as it can cause intrauterine infection of the baby. This leads (in some cases) to premature termination of pregnancy and the passage of amniotic fluid.

To get rid of gardnerella, pregnant women usually use the following medicines in the form of suppositories: Metrogil, Trichopolum, Clione, Metronidazole or Ornidazole. The main difference between these drugs is the fact that they do not affect the development of the fetus in any way. But remember, you can use any medications (even those that are allowed during pregnancy) only after the end of the first trimester of the gestational period. Typically, doctors begin to treat gardnerellez in pregnant women, starting with the twentieth week.

Contraindications and side effects

As a rule, the suppository from Gardnerella and ureaplasma does not have any serious contraindications. They can not be used in cases of intolerance of the main active components of candles, allergic reactions to active substances of preparations, in the first months of pregnancy, and also during lactation.

Side effects from the use of such suppositories are extremely rare. In some cases, at the first stages of therapy a woman may feel a slight burning or itching in the vagina. Sometimes there are allergic reactions, nausea, vomiting, headache, irritation, depression, loss of sleep or appetite. In such cases, you must immediately stop the therapy and seek help from a doctor.

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Overdose

Since such drugs are administered by one candle, no cases of overdose have been observed.

Interaction with other drugs

The interaction of suppositories against gardnerella and ureaplasma with other drugs depends entirely on the active ingredients that are their basis. So, for example, the suppository "Terzhinan" interacts with various means without any weakening or strengthening of mutual effects. But "Dalacin" is not recommended to be taken with muscle relaxants, as it can strengthen their action. If you use "Metrovit" together with any drugs based on lansoprazole, the patient can develop stomatitis, glossitis.

Storage conditions and shelf life

Usually the suppository from gardnerella and ureaplasma is stored in a dry, cool place (the air temperature is not above +25 degrees). It is very important to keep them away from children. For more information, you can read the instructions that are always in the package of medications.

Suppositories are stored for no more than three years under proper storage conditions. Please note that you can not use any medications after this period, as this can lead to complications and increased side effects.