Snorex snoring: Is it effective?

When a person suffers from ronchopathy, that is, it snores during sleep, the vibration of the tissues in the throat that occurs when air passes through can reduce such means as Snorex spray from snoring.

There are many drugs that are said to make breathing easier at night, for example, by acting on the muscles of the respiratory tract. Since it has not yet been proven that no medicine can help reduce snoring during sleep, currently drugs cannot be used as part of the main therapy for obstructive sleep apnea. But these drugs can be used to treat certain conditions that can cause snoring in a dream or aggravate an existing apnea.[1], [2]

Indications Snorex snoring

Indications for use of this tool - snoring, release form - solution in a bottle (with nozzles for instillation and for spraying).

Means like Snorex do not belong to drugs and are most often sold not in pharmacies, but through the Internet. In any case, this is how Snorex and all its analogs are acquired, including SnoreX sprays (with mint, lemon, fennel, clove, lavender, eucalyptus and thyme oils); Sonex (with essential oils of mint, eucalyptus, cinnamon and echinacea extract) and Silenor of identical composition; Stop Hrap Nano (with peppermint, lemon, and sage essential oils); Slipex (containing oil of mint, ironery, menthol and eucalyptol); Sprax Restox and Minusnor.

Note that, under the same name SnorEx, there is an intraoral prosthesis that causes the tongue to move forward and is used to treat obstructive sleep apnea. However, some studies have proven the low efficiency of the SnorEx prosthesis, so the prosthesis should not be administered without contacting a sleep lab.[3], [4], [5]

Read also -  Treatment of snoring with the help of sprays.

Release form

In fact, the pharmacokinetics of most herbal remedies, including biologically active complexes, is absent in their descriptions, since they are poorly understood. It is indicated only that Snorex - in the form of a two-phase concentrated colloidal solution (fine) - “completely absorbed,” that is, it means penetration into the tissues, gastrointestinal tract and entering the bloodstream.

Pharmacodynamics

Since Snoreks spray is not a drug, but a complex of biologically active substances (plant and non-plant), their mechanism of action has a descriptive form: they help eliminate inflammation of the nasopharynx and larynx, reduce nasal secretions and improve nasal breathing, increase muscle tone of the soft palate, and calm the nerves.

The distributors of this tool have focused the potential consumer’s attention on the three components of Snorex, but its composition contains up to fifty ingredients in the form of extracts and bioconcentrates. But in the replicable description, the main action is associated with propolis, calendula and sage.

Propolis, which has many valuable pharmacological properties, is used to treat tonsillitis and stomatitis, since it has antimicrobial and antifungal effects. Also, bee glue is an antioxidant and local immunomodulator (due to the activation of macrophages by the flavonoids hesperidin and quercetin contained in it) and antioxidant (due to a complex of phenolic compounds, in particular, caffeic acid), it stimulates tissue metabolism and regeneration (by enhancing proliferative processes). Propolis has an astringent effect and strengthens the walls of blood vessels.[6]

Propolis contains phenolic compounds, esters, flavonoids, terpenes, beta-steroids, aromatic aldehydes and alcohols, twelve different flavonoids, namely pinocembrin, akacetin, chrysin, rutin, luteolin, kaempferol, apigenin, myricinetin, catechin, iprinen, nurinen, myrin, cristin.; two phenolic acids, caffeic acid and cinnamic acid; and one stilbene derivative called resveratrol. Propolis also contains important vitamins such as vitamins B1, B2, B6, C and E, and useful minerals such as magnesium (Mg), calcium (Ca), potassium (K), sodium (Na), copper (Cu), zinc (Zn), manganese (Mn) and iron (Fe). Several enzymes, such as succinic dehydrogenase, glucose-6-phosphatase, adenosine triphosphatase and acid phosphatase.[7], [8]

[9], [10]Calendula drug is also known to contain antimicrobial and anti-inflammatory properties, containing a complex of terpenoids, triterpene glycosides, flavonoids and sterols. They reduce puffiness and promotes the regeneration of damaged tissues, reduce oxidative stress of tissues. Usually, calendula is used in the local treatment of tonsillitis, oral diseases, including stomatitis and periodontal disease. On the central nervous system calendula has a calming effect.[11]

Similarly, sage is used, which has anti-inflammatory, antimicrobial and astringent properties due to its essential oils, tannins, terpenes, organic acids, flavonoids and polyphenolic compounds (for example, carnosic acid, rosmarinic acid and caffeic acid) with strong antioxidant action. Studies show that sage can be used to treat symptoms in many serious and life-threatening diseases, such as depression, dementia, obesity, diabetes, lupus, heart disease, and cancer.[12]

In addition, the composition of Snow Snail includes: extracts containing theobromine holly; Serpentine rauwolfia (lowering blood pressure due to the presence of reserpine and aymalin alkaloids); [13]lofanta or fennel multicore (stimulates the digestive and immune systems); [14]legume plants lespedeza (with psychoactive alkaloid bufoteninom); [15]ascomycete fungus Cordyceps (with immunomodulatory properties; can be used to treat conditions such as night sweats, hyposexuality, hyperglycemia, hyperlipidemia, asthenia after a serious illness, respiratory diseases, renal dysfunction, renal failure, arrhythmias and other diseases of the heart and liver); [16]beaver jet (containing fatty aromatic ketone acetophenone, which gives a hypnotic effect); used in homeopathy extract wax moth (Galleria mellonella) [17], etc.

How these and other components contribute to the prevention of snoring is not explained, but the description states that the agent acts in a complex and multifaceted manner on the condition and function of the respiratory, cardiovascular and endocrine systems, as well as on the immune system and the central nervous system.

Dosing and administration

In the morning (meal) Snoreks should be used as drops (three drops instilled at the root of the tongue).

During the day (half an hour before meals) the product is sprayed into the throat, on the palate and glands (no more than two clicks on the cap of the spray nozzle), before using the solution in the vial should be shaken.

At bedtime, spraying is performed again, but it is not necessary to shake the solution.

The recommended duration of the use of the Snorex is one month.

Application for children

In the description of the means noted the possibility of its use for children - with ENT infections. Sage oil contains convulsive substances such as thujone, camphor and cyneol in different proportions that can cause generalized tonic-clonic seizures [22], therefore containing sage extract limits Snorex’s use to three years of age, and the presence of homeopathic components and substances affecting the central nervous system causes doubt about the feasibility of its use for children.

Use Snorex snoring during pregnancy

The description of the product indicates that the product does not have a natural and teratogenic effect, therefore its use is possible during pregnancy.

However, the sage leaf extract contained in Snorax is not recommended for pregnant women, since this plant can cause contractions of the uterus muscles, as well as reduce the level of progesterone.

Sage essential oil is believed to stimulate labor by increasing the level of oxytocin. Sage sage essential oil contains sclareol, which has a structure similar to estrogen and has an estrogen-like effect. Estrogen enhances the release of oxytocin. Studies have shown that inhalation of the sage essential oil aroma tended to increase the level of oxytocin 15 minutes after inhalation, which was measured by inhalation.[18]

Contraindications

Snore spray Snoreks is contraindicated in case of hypersensitivity to its components, as well as in the history of allergies to products produced by bees. [19]

Contraindications should also include bronchial asthma, COPD and hypotension.

Side effects Snorex snoring

Such a section in the manual with Snoreks (more precisely, in the information sheet for consumers, attached by the manufacturer - Sashera-Med LLC, Biysk, Altai Territory) is absent. But it should be borne in mind that, for example, propolis, when sprayed into the throat, can cause dry mouth, laryngeal spasm, shortness of breath and angioedema.[20]

The side effects of rauwolfia alkaloids include nausea, vomiting, decreased heart rate, weakness, depression, increased anxiety, extrapyramidal symptoms such as orofacial dyskinesia and tremor. [21]

Overdose

Information is absent.

Interactions with other drugs

Data on drug interactions in the description are not given.

Storage conditions

The product should be stored at t ˂ + 25 ° С, in a dark, dry place.

Shelf life

Shelf life - 24 months.

Reviews

Reviews of the effectiveness of this tool are different. Do not be surprised if Snoreks does not help from snoring. The etiology of  snoring  can be associated with anatomical features: a thickened soft palate, elongated uvula (palatine uvula), enlarged nasopharyngeal tonsils, curvature of the nasal septum. [23]In such cases, ronchopathy is not treated with sprays.