This substance - a very effective anorektik, and, of course, that those who want to lose weight and read rave reviews, which are many, the question arises: What is dangerous Sibutramine?
Of course, like any substance, it can cause allergies. In most cases - this is not an anaphylactic shock, but a more harmless reaction of the body, for example, a rash from Sibutramine. Unpleasant, but not dangerous. Stop taking - it will scratch and pass.
A more serious consequence is addiction. This drug is not recommended for more than one year, but people who started taking it, often can not stop, they develop a real drug addiction, which, in fact, is a subset of drug addiction. Not everyone. However, who can guarantee that his body will be resistant to this property of this drug?
There will not be a true narcotic buzz from Sibutramine, but when canceled, which is recommended to be carried out gradually, there may appear sensations similar to "breaking". This happens even with a short, three months, taking the drug. It is dizziness and migraines, sleep disturbances and anxiety, increased excitability or apathy and thoughts of suicide. Sibutramine has a direct effect on the brain and central unequal system. This is how he fights overeating and overweight. But it is not always possible to influence the psyche and the nervous system without undesirable consequences. The first appointment of Sibutramine was accompanied by severe neuropsychic disorders, suicides, deaths from acute cardiac and cerebral pathologies, patients became dependent on the drug and its long reception turned into sad consequences. Current dosages of Sibutramine are much lower than those recommended at the beginning, the drug is better purified, but the undesirable effects, albeit less pronounced, are still there. During the period of therapy with this medicine, it is impossible to perform work at altitude, drive vehicles, work with mechanisms requiring increased concentration of attention. This drug is contraindicated in people who have a history of alcoholic or toxic addiction or anamnesis, since the effects will overlap.
The instructions to the drug indicate that the side effects most often occurred in the first month of treatment, and if it continued, the frequency and intensity of these effects decreased with time. Negative actions, in the main, were reversible and passed with the withdrawal of the drug.
The most common were heart palpitations, hypertension, hyperemia of the skin with sensations of heat, constipation, a complete lack of appetite, exacerbation of hemorrhoids, nausea, a feeling of dryness in the oral cavity, insomnia, fainting, numbness in parts of the body, panic attacks, increased sweating, perversion of taste.
In the post-registration study SCOUT, initiated by the relevant body of the European Union after many cases of severe adverse events, in which many patients with obesity and a high likelihood of cardiovascular disease participated, the following data were obtained: risk of non-fatal (!) Heart attack, stroke, heart attack of patients taking sibutramine increased by 16% compared with those who took placebo. However, which is very comforting, with the help of resuscitation it was possible to save 1.4% more patients who took this drug. But the deaths, both from vascular pathologies, and from all causes, in both groups of patients were met with the same frequency.
There were undesirable effects in the form of allergies from minor rashes to anaphylactic shock. In the blood, the number of platelets decreased, that is, the blood was poorly folded, there were cases of autoimmune damage to the walls of blood vessels (hemorrhagic purpura), mental disorders, as already mentioned above. In these cases, treatment was recommended to be discontinued.
The nervous system reacted to the drug with convulsions, short-term failures in memory, amnesia.
Pain syndromes in the head, back, ears, visual and hearing disorders, digestion, ENT diseases, herpes. The list of side effects is endless. He concludes the report that occasionally withdrawal syndrome is accompanied by a headache and increased appetite (!).
Women who plan to give birth after the course of Sibutramine, it makes sense to seriously think about. The drug is teratogenic, its ability to cause mutations has not yet been confirmed, but use this tool for a short time and the main thing - it is often not official. Therefore, additions to the list are still possible.