Medical expert of the article
New publications
Preparations
Panthekrem
Last reviewed: 23.04.2024
All iLive content is medically reviewed or fact checked to ensure as much factual accuracy as possible.
We have strict sourcing guidelines and only link to reputable media sites, academic research institutions and, whenever possible, medically peer reviewed studies. Note that the numbers in parentheses ([1], [2], etc.) are clickable links to these studies.
If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please select it and press Ctrl + Enter.
Panthekram is a medicine used for ulcers and wounds. Promotes healing. The active substance is dexpanthenol.
Indications of the panthecemmas
The medicine is shown:
- as a preventive agent for the treatment of cracks and reddened dry patches of skin;
- to accelerate the processes of epithelization, as well as healing after microdamage (this includes small scratches with burns);
- in the case of skin irritations due to photo / radiotherapy or ultraviolet irradiation;
- with diaper dermatitis;
- with ulcerous lesions of the skin in a chronic form;
- with anal fissures, eruptions of the uterine neck or pressure sores;
- after skin transplantation;
- as a means for treating skin patches during the use of corticosteroids or after their withdrawal;
- with prophylactic treatment of mammary glands of lactating women, as well as to eliminate cracks, and along with this, irritation symptoms in the nipple area.
Release form
Available in the form of cream, in tubes of 30 g. Inside a separate package contains 1 tube.
Pharmacodynamics
The active component of the drug (dexpanthenol) is a provitamin from group B5. Inside skin cells, the substance quickly transforms into pantothenate and acts on the body as a vitamin. In this case, absorption of dexpanthenol occurs faster than a similar process involving pantothenate (with external application).
Pantothenate is one of the elements of coenzyme type A (CoA). In this form (acetyl coenzyme A (CoA)), it is the main participant in the metabolic processes inside each cell. That is why pantothenate is necessary for the processes of formation and healing of affected areas of mucous membranes and skin.
Pharmacokinetics
After external application, dexpanthenol is absorbed quickly enough through the skin. Inside the skin cells, it immediately converts to pantothenate and joins the internal group of this vitamin.
Inside the blood, pantothenate is synthesized with plasma albumin, as well as β-globulin. The concentration of a substance in a healthy adult reaches approximately 500-1000 mg / l in the blood, as well as 100 mg / l within the serum.
Pantothenate does not pass the process of biotransformation. The excretion of the substance is carried out in an unchanged form - about 60-70% of the substance is excreted in the urine, and the remainder is excreted with feces. For a day, an adult with a urine excretes 2-7 mg of the substance, and in children - about 2-3 mg.
Dosing and administration
To accelerate the processes of epithelialization, along with the healing of skin lesions, it is required as a preventive measure to treat it with cream once or several times a day (depending on the need).
Treatment of mammary glands of nursing mothers - application of the medicine to the nipples at the end of each feeding procedure.
To eliminate defects on the mucous membrane of the uterine neck, you should use the cream once or several times a day (the frequency depends on the need).
Preventive treatment in infants - apply medicine every time a diaper is changed.
The duration of the treatment course is prescribed by the doctor. The figure is individual, the decision takes into account the presence on the skin of the clinical symptoms of damage.
Since the cream is absorbed fairly quickly, it is allowed to be used in the treatment of wet wounds, and in addition to this damage to the face and skin under the hairline. The distribution on the surface of the skin is easy, which makes it possible to apply Panthekrem in the treatment of painful sunburn, as well as other minor burn injuries.
Use of the panthecemmas during pregnancy
There is no information about the risk in case of using the cream during pregnancy or lactation. It is unlikely that fetotoxic effects may occur. But in any case, pregnant women should apply the cream only for medical purposes.
If used to eliminate cracks in the nipples during lactation, it is required to rinse the medicine before the feeding procedure.
Side effects of the panthecemmas
The use of the cream can lead to the development of side effects with manifestations on the skin and the subcutaneous layer, as well as the immune response. There is information about the manifestations of skin allergy: the development of an allergic or contact form of dermatitis, and in addition erythema with pruritus, hives with eczema, and rashes. Bubbles may appear on the skin and irritation may occur.
Storage conditions
Keep the cream out of the reach of children. Do not freeze the medicine. Temperatures are a maximum of 25 ° C.
[10]
Shelf life
Panthelex is suitable for use within 3 years from the date of release of the medicine.
Attention!
To simplify the perception of information, this instruction for use of the drug "Panthekrem" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.