Panthenol

Panthenol is a medicine that helps the healing process of wounds of various origins.

[1], [2], [3]

Indications of the pantenola

The ointment is indicated in such cases:

• to speed up the epithelization and the healing process of skin areas exposed to microdamages (for example, minor abrasions and faint burns), and in addition to treating skin irritations (arising from ultraviolet irradiation or after photo and radiotherapy procedures), bedsores and skin ulcers chronic form). It is also used for the removal of anal fissures, with erosions of the uterine neck and after skin transplantation;
• in the treatment or as a prophylaxis for the treatment of dry and rough or cracked skin;
• constant prevention of breast diseases in nursing mothers, and in addition to eliminating cracks and irritations in the nipple;
• in the treatment of infants - elimination of dermatitis diaper type or prevention of this pathology;
• treatment of the skin by persons who use corticosteroids locally (or after completion of such treatment course).

Release form

Produced in the form of ointment, in a tube of 30 g. Inside a single pack contains 1 tube of ointment.

Panthenol Aerosol

Aerosol Panthenol should be used to remove various damages to the mucous membranes and skin (among them burns and abrasions), as well as aseptic wounds left after surgery and dermatitis (bladder and bullous forms). In addition, it is used for skin grafts.

Panthenol capsules 40 mg

Panthenol capsules are used in the treatment of alopecia, stratification and fragility of the hair, as well as to eliminate excessive dandruff. Along with this, the drug is used for problems with hair growth, increased secretion of sebaceous glands, hives with eczema, rashes and dermatoses (complicated by itching). Also capsules should be taken with allergic form of rhinitis, inflammation of the gums and hyperhidrosis of the extremities.

Use the medication after eating. Capsules are swallowed whole, washed down with water.

For adolescents from 15 years and adults, the dose is equal to 2 capsules three times a day. Children 3-6 years - 1 capsule once per day. Children 6-12 years old - 1 capsule twice a day. Children 12-15 years old - 1 capsule three times a day.

The duration of the therapeutic course is 1-3 months.

Pharmacodynamics

The active component of the drug is dexpanthenol, which inside the cells is quickly converted into a pantothenate substance, after which it begins to act on the body as a vitamin. Absorption of dexpanthenol after local application occurs faster than a similar process of pantothenate.

Pantothenic acid is one of the constituent elements of coenzyme type A (CoA). This component, acquiring the form of acetylcoenzyme type A, becomes the main participant in the processes of cellular metabolism. That is why pantothenate is an essential element in the healing and recovery of injured mucous membranes and skin.

Pharmacokinetics

Dextpanthenol is quickly absorbed into the body through the skin, after which it is converted to pantothenate and incorporated into the internal vitamin depot.

The transformed substance is synthesized with a plasma protein (mostly albumins along with β-globulins). Pantothenic acid in healthy people is approximately 500-1000 μg / L in the blood, as well as 100 μg / L in the blood serum.

Pantothenate is not metabolized and excreted unchanged from the body. Urinary excretion in an adult is 2-7 mg per day, and in a child 2-3 mg.

Dosing and administration

When removing superficial wound injuries of any nature, as well as for preventive treatment of dry / rough or cracked skin, ointment should be used once a day. But if necessary, it is allowed to increase the frequency of application procedures.

In the treatment of mammary glands in nursing mothers, the areas of the nipples should be treated after each feeding procedure.

To eliminate defects that have formed on the mucous membrane of the uterine neck, it is necessary to use the ointment once or several times a day (under the supervision of the attending doctor).

During the treatment of infants, Panthenol ointment should be applied together with each change of diapers.

[4], [5]

Use of the pantenola during pregnancy

According to existing information, the use of Panthenol does not pose any risk to pregnant or lactating women. However, during pregnancy, it is recommended to use the medicine only as prescribed by the doctor.

During the treatment of cracks in the nipples during lactation, it is required to rinse the medicine before the feeding procedure.

Contraindications

Contraindications are hypersensitivity to dexpanthenol or other components of the drug.

Side effects of the pantenola

The use of ointment can cause the development of side effects on the skin and the subcutaneous layer, as well as from the side of immunity: manifestations of allergy in the form of dermatitis (allergic or contact form), rashes, itching, urticaria and eczema, as well as skin irritation, erythema and the appearance of vesicles.

Storage conditions

The medicine must be kept in a place inaccessible to small children. The temperature should not exceed 25 ° C.

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Shelf life

Panthenol in the form of an ointment can be used in the period of 5 years, and in the form of a spray and capsules - within 3 years from the date of release of the medicine.