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Ozerlik
Last reviewed: 03.07.2025
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Ozerlik is a fluoroquinolone antibiotic with a broad spectrum of antibacterial activity. Manufacturer - Kusum Healthcare (India). Other trade names: Gatifloxacin, Gatimak, Gatibact, Gatispan, Bigaflon, etc.
Indications Ozerlik
Ozerlik is intended for the treatment of exacerbations of bronchitis, pneumonia, lung abscess, chronic otitis, sinusitis; chronic urological diseases of bacterial etiology (cystitis, urethritis, pyelonephritis); infectious lesions of various localizations, including sepsis.
The drug can be used in case of infection and inflammation of the cornea and mucous membrane of the eye. And also in case of ineffectiveness of drugs against tuberculosis of the lungs.
Release form
Release form: tablets of 200 and 400 mg.
Pharmacodynamics
The active substance of Ozerlik - gatifloxacin-8-methoxyfluoroquinolone - has a bactericidal effect against such gram-negative and gram-positive pathogens as Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes, Haemophillus influenzae, Haemophilias parainfluenzae, Klebsiella pneumoniae, Klebsiella oxytoca, Moraxella catarrhalis, Escherichia coli, Enterobacter cloacae, Enterobacter aerogenes, Proteus vulgaris, Morganella morganii, Bacteroides distasonis and others, including those resistant to macrolides and beta-lactam antibiotics.
By blocking the bacterial enzyme DNA topoisomerase, the active substance of this drug prevents DNA replication and division of microorganisms, causing their death.
Pharmacokinetics
Ozerlik penetrates into most tissues and biological fluids; bioavailability is almost 96%; the maximum concentration of the drug in the blood is observed on average 90 minutes after taking a therapeutic dose; about 20% of the active substance binds to blood plasma proteins.
The drug undergoes biotransformation in the liver, 80% of gatifloxacin is excreted from the body by the kidneys (with urine), the half-life ranges from 7 to 14-15 hours.
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Dosing and administration
Ozerlik should be taken orally. The standard dose is 400 mg once a day. The duration of the course of treatment is determined by the attending physician depending on the specific disease and the patient's condition.
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Use Ozerlik during pregnancy
Use during pregnancy, like most drugs in the fluoroquinolone group, is prohibited due to the high risk of teratogenic effects on the fetus.
Contraindications
Contraindications to the use of this drug are individual hypersensitivity to fluoroquinolone antibiotics, diabetes mellitus, hypercalcemia, severe liver failure, childhood (under 18 years).
Side effects Ozerlik
The most common side effects of Ozerlik include: nausea, vomiting, abdominal pain, intestinal disorders; headache, dizziness; swelling of the face and mucous membranes; visual impairment; insomnia or increased sleepiness; increased blood pressure, irregular heartbeat; cramps, muscle pain and tendon ruptures; decreased blood sugar, liver failure.
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Overdose
Ozerlik is expressed in the increase of side effects, as well as prolongation of the QT interval. The latter creates a risk of life-threatening cardiac arrhythmia. In case of overdose, gastric lavage and symptomatic treatment are performed.
Interactions with other drugs
Due to insufficient experience of clinical use of Ozerlik in combination with drugs of other pharmacological groups and the lack of studies of their interaction, manufacturers do not recommend prescribing Ozerlik simultaneously with histamine H2-receptor antagonists, antiarrhythmic drugs, tricyclic antidepressants and hypoglycemic drugs taken orally.
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Storage conditions
Storage conditions: in a place protected from light, at room temperature.
Shelf life
Shelf life: 24 months.
Attention!
To simplify the perception of information, this instruction for use of the drug "Ozerlik" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.