Nazole Kids

Nasol diet is an α-adrenomimetic from the group of decongestants, which is effectively used to treat rhinitis in children. The active ingredient of the agent is phenylephrine, whose ATX code is 1101AA04.

[1], [2], [3]

Indications Nazole Kids

Nasolitis is prescribed to relieve symptoms and eliminate rhinitis:

• with ARVI, influenza, acute respiratory disease, angina;
• with allergic rhinitis;
• with hay fever;
• with sinusitis, sinusitis, salpingitis

[4], [5], [6], [7],

Release form

Nasol is given in the form of a convenient intranasal spray, 15 ml or 30 ml of 0.25% solution. A polyethylene bottle, with a screw cap and a built-in spraying device. The cap has a conical shape with a tread ring, which guarantees the integrity of the packaged vial.

Spray Nazole kidney is a transparent, almost colorless liquid with the aroma of eucalyptus. The composition of the spray is phenylephrine g / x 0.25 g, as well as additional substances in the form of benzalkonium chloride, cineole, glycerol, macrogol, sodium dihydrogen phosphate, etc.

[8]

Pharmacodynamics

Phenylephrine g / x - the main constituent Nasol diet - reduces the degree of edema and redness of the mucous membranes in the nose, reduces exudation, helps to resume free breathing, lowers the pressure in the nasal sinuses and in the middle ear cavity. These properties are characteristic of phenylephrine, since this substance is an agonist of α1-adrenergic receptors (sympathomimetic substance). Its main ability is the narrowing of the vessels, which occurs by activating the α1 receptors in the superficial mucous layer. The use of Nazol kides prevents the development of complications associated with congestion in the upper respiratory tract.

[9], [10], [11]

Pharmacokinetics

Spray Nazol kides is applied topically, therefore its active ingredient phenylephrine practically does not enter the systemic bloodstream. As a result, there is no reliable data on the pharmacokinetic properties of the drug.

[12], [13], [14], [15], [16], [17], [18], [19]

Dosing and administration

Nasol is intended only for intranasal use. Before use, turn the bottle vertically and press your fingers on the spray gun.

Children from six to 12 years spend up to 3 injections in each nostril opening. Frequency of injection - after 4 or more hours.

The duration of therapy is no more than three or five days in a row.

Before the procedure, it is recommended to clean the nasal passages from mucus. It is not necessary to tip your head when injected.

[27], [28]

Use Nazole Kids during pregnancy

Spray Nazol kides is used in pediatric practice, so studies on the use of Nazol kids were not carried out by pregnant and lactating women. Since the drug is recommended for use in children from the age of six, women should choose other medications during pregnancy, after consultation with the attending physician.

Contraindications

• Propensity to allergies to individual components of the drug Nazol kids.
• Diseases of the heart and blood vessels (eg, heart failure or coronary sclerosis).
• Steady rise in blood pressure.
• Hyperfunction thyroid.
• Diabetes.
• Pregnancy and lactation period.
• Children up to the age of six.

[20], [21], [22]

Side effects Nazole Kids

Adverse symptoms during the period of treatment with the drug Nazol kyds are rare and can manifest themselves as local or systemic reactions:

• burning, soreness and discomfort in the nasal cavity;
• pain in the head, dizziness;
• heart rhythm disturbances;
• increased blood pressure;
• hyperhidrosis;
• blanching of the skin;
• trembling limbs;
• sleep disorders.

After the end of the use of the drug Nazolides, the side manifestations pass without any treatment.

[23], [24], [25], [26]

Overdose

Special information on the possibility of an overdose Nazol kids is not provided. In rare cases, heart rhythm disturbances are likely, headache, heaviness in the legs, increased blood pressure, irritability

[29], [30], [31], [32]

Interactions with other drugs

Nasol diet is a vasoconstrictor, so its effect may be enhanced after combined use with MAO inhibitor drugs (eg, procarbazine) or with tricyclic antidepressants.

Hormonal thyroid preparations increase the risk of developing cardiac insufficiency, especially if coronary sclerosis is present.

[33], [34], [35]

Storage conditions

Nazel carbides are stored at room temperature, not exceeding + 25 ° C. When choosing a storage location, you should target dark, dry areas that are out of the reach of children.

[36]

Shelf life

Shelf life Nasol diet is up to 2 years, after which it is recommended to discard the medication.

[37],