^

Health

Nazol

, medical expert
Last reviewed: 09.08.2022
Fact-checked
х

All iLive content is medically reviewed or fact checked to ensure as much factual accuracy as possible.

We have strict sourcing guidelines and only link to reputable media sites, academic research institutions and, whenever possible, medically peer reviewed studies. Note that the numbers in parentheses ([1], [2], etc.) are clickable links to these studies.

If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please select it and press Ctrl + Enter.

Intranasal Spray Nasol is a topical agent that is prescribed for the treatment of the common cold. According to the ATX classification, according to the active substance, Nazolu is assigned code R01A A05. 

trusted-source[1]

Indications Nazol

Nasol is prescribed to eliminate symptoms of acute rhinitis:

  • with discharge from the nose (mucous, mucopurulent);
  • for treatment of a vasomotor runny nose;
  • for the treatment of an allergic rhinitis;
  • with swelling of the mucous membranes of the nasal cavity and nasal sinuses, with sinusitis.

In addition to treatment, Nazol can be used to prepare the patient for the conduct of therapeutic and prophylactic manipulations in the nasal cavity.

trusted-source[2], [3], [4], [5], [6], [7]

Release form

Intranasal preparation Nazol is available in aerosol plastic bottles with dispenser, 15 or 30 ml, packed in a cardboard pack.

 In 1 ml of the drug contains:

  • oxymetazoline g / x - 500 mcg;
  • additional ingredients are represented by benzalkonium chloride, benzyl alcohol, macrogol, povidone, propylene glycol, etc.

Nasol belongs to the list of OTC medicines.

trusted-source[8], [9], [10]

Pharmacodynamics

Nasol is a medication from the category of external vasoconstrictive drugs. The active ingredient oxymetazoline has an α-adrenergic property, since it is a synthetic adrenomimetic.

Nazol successfully blocks rhinorrhea - discharge from the nose of any etiology, including allergic. Active oxymetazoline instantly narrows the surface vessels, reduces the signs of swelling of the tissues, facilitates breathing through the nose and restores the perception of odors. At the same time, the opening of the mouth of the nasal sinuses opens, and free breathing resumes.

trusted-source[11], [12], [13], [14], [15], [16]

Pharmacokinetics

Oxymetazoline acts 10-15 minutes after applying the drug to the mucous membranes. The duration of the vasoconstrictive effect is approximately 12 hours.

The systemic distribution of the active component is negligible. Excretion is carried out through the urinary and digestive system. The half-life is from 5 to 8 days.

trusted-source[17], [18], [19], [20], [21], [22], [23], [24], [25]

Dosing and administration

Nasol is applied by intranasal administration. The spray tip is inserted shallowly into each nasal passage and press the atomizer with your finger while simultaneously taking a deep breath through the nose.

It is not necessary to tip your head when using a spray.

Children after 6 years and adults spend 1-3 injections into each nostril opening.

The frequency of the drug - twice a day, in the morning and at night. The duration of the treatment course is a maximum of 3 days.

trusted-source[37], [38], [39], [40]

Use Nazol during pregnancy

Use of medication Nazol pregnant women is not recommended. If this remedy is necessary, the recommended dosage should be adhered to, carefully assessing the likely risks to the developing fetus.

In the period of breastfeeding, it is necessary to use funds based on oxymetazoline with great care, but it is better to refuse them altogether.

Contraindications

  • Individual hypersensitivity to oxymetazoline, a tendency to allergies to other components.
  • Atrophy of the mucous membranes of the nose.
  • Treatment with means-inhibitors MAO, or other drugs that increase blood pressure.
  • Glaucoma, increased intraocular pressure.
  • Acute heart attack, stroke, hypertensive crisis.
  • Pregnancy and lactation period.
  • Heart rhythm disorders.
  • Pheochromocytoma.
  • Disturbed metabolism (thyroid disease, diabetes mellitus).
  • Hyperplasia of the prostate.
  • Children under 6 years.

trusted-source[26], [27], [28], [29], [30], [31]

Side effects Nazol

With frequent and prolonged use of Nazol spray, the following effects are possible:

  • sensation of itching and burning in the nasal cavity;
  • dryness of nasal mucosa;
  • habitual stuffiness in the nose;
  • increased heart rate, increased blood pressure;
  • conjunctivitis;
  • dyspepsia;
  • allergic manifestations (rash, hives, angioedema);
  • atrophic changes in the mucosa, frequent bleeding from the nose;
  • sleep disorders, irritability;
  • increased fatigue, headaches.

After the end of treatment, side effects, as a rule, are eliminated.

trusted-source[32], [33], [34], [35], [36]

Overdose

When using Nasol spray for longer than four days, and if the medicinal solution is accidentally swallowed, there may be signs of overdose:

  • spasms of peripheral vessels;
  • attacks of nausea and vomiting;
  • oppression of the central nervous system;
  • heart rhythm disturbances;
  • insufficiency of cardiac activity;
  • collapse;
  • increased allocation of sweat;
  • pulmonary edema, respiratory function disorders;
  • blanching of the skin;
  • convulsions, nervous disorders, strong emotional arousal.

Often overdose is characterized by oppression of the central nervous system, which is manifested by fatigue, drowsiness, a drop in blood pressure, the development of a coma.

If the product is swallowed, it is recommended to wash the stomach, take sorbent preparations (activated charcoal, sorbex, etc.).

trusted-source[41], [42], [43], [44], [45], [46], [47], [48]

Interactions with other drugs

With the combined use of other drugs that can narrow the blood vessels, there may be an increase in side effects, in particular, an increase in blood pressure.

Oxymetazoline impairs the effect of other nasal solutions and lengthens the period of their absorption, and also enhances the effect on the nervous system of MAO inhibitory agents.

The long-term use of Nazel is undesirable, since this can provoke the development of atrophic changes in the mucosal epithelial tissue. For the same reasons, several vasoconstrictors should not be used simultaneously.

trusted-source[49], [50], [51], [52], [53], [54], [55]

Storage conditions

Nasol must be stored in a dark place, away from children's access areas. The optimum temperature regime for the preservation of the drug is from +2 to + 25 ° C.

trusted-source[56], [57]

Shelf life

Shelf life of the spray Nazol - up to 3 years.

trusted-source[58], [59], [60], [61]

Attention!

To simplify the perception of information, this instruction for use of the drug "Nazol" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.

Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.

Translation Disclaimer: For the convenience of users of the iLive portal this article has been translated into the current language, but has not yet been verified by a native speaker who has the necessary qualifications for this. In this regard, we warn you that the translation of this article may be incorrect, may contain lexical, syntactic and grammatical errors.

You are reporting a typo in the following text:
Simply click the "Send typo report" button to complete the report. You can also include a comment.