Nazol Baby

External remedy for the common cold Nazol baby is an α-adrenomimetic drug from a number of decongestants. The active ingredient of the agent is phenylephrine, which according to the ATX classification has the code 1101AA04.

Indications Nazol Baby

Nasol baby is prescribed to eliminate symptoms of rhinitis:

• with respiratory viral infections, acute respiratory infections;
• with allergic rhinitis;
• with hay fever;
• with sinusitis, salpingoote. 

[1], [2], [3]

Release form

Nazel baby is released in the form of intranasal drops, 5 ml, 10 ml, 15 ml or 30 ml 0.125% solution. The bottle is polyethylene, with a screw cap and a built-in spout. The cap has a conical shape with a tread ring ensuring the integrity of the packaged vial.

Nazol baby's drops are a transparent, almost colorless liquid, containing phenylephrine g / 0.125 g, as well as additional substances in the form of benzalkonium chloride, glycerol, macrogol, sodium dihydrogen phosphate, etc.

Pharmacodynamics

Phenylephrine g / x - the main active ingredient Nazol baby - eliminates swelling and redness of the mucous membranes, reduces exudative discharge, helps to resume breathing freedom, reduce pressure in the nasal sinuses and in the middle ear cavity. These properties are characteristic of this active component, since it is an α1-adrenergic receptor agonist (sympathomimetic substance). Its main action is vasoconstriction, which occurs by the activation of α1-receptors in the superficial mucous layer. Due to this, stagnant signs in the tissues weaken, the patency of the mouth of the sinuses improves.

[4], [5], [6], [7], [8]

Pharmacokinetics

The drug Nazol baby and, in particular, its active ingredient phenylephrine, practically does not enter the systemic bloodstream, so there is no data on the pharmacokinetic properties of the drug.

[9], [10], [11], [12]

Dosing and administration

Nasal baby is intended only for instillation into the nasal cavity. To apply drops, it is necessary to topple the bottle upside down and squeeze it slightly with your fingers.

The dosage of the drug is calculated as follows:

• children from birth to one year of age - 1 drop, once every 6 or more hours;
• children from one to six years - 1-2 drops once every six hours;
• children from six years of age and adults - 3-4 drops at a time.

The duration of therapy is not more than 3 consecutive days.

Before instillation it is recommended to clean the nasal passages from the mucus and toss up the head.

[18], [19], [20],

Use Nazol Baby during pregnancy

Adequate experimental experiments on the use of Nazol baby in pregnant and lactating women were not conducted. Since the drug is recommended for use in children from the age of six, women should use other medicines recommended by the doctor during pregnancy.

Contraindications

• Propensity to allergic reactions to individual components of Nazol baby.
• The pathology of the heart and blood vessels (in particular, ischemic heart disease or coronary vascular sclerosis).
• Persistent increase in blood pressure.
• Increased thyroid function.
• Diabetes.
• Pregnancy and lactation period.
• Children up to the age of six.

[13], [14]

Side effects Nazol Baby

Adverse symptoms during the period of treatment with Nazol baby are rare and can occur as local or systemic reactions:

• itching, soreness and discomfort in the nasal cavity;
• pain in the head, dizziness;
• tachycardia, heart rhythm disturbances;
• increased blood pressure;
• increased sweating;
• blanching of the skin;
• trembling in the fingers of the hands;
• sleep disorders.

After the end of treatment with Nazol baby, the side manifestations pass independently.

[15], [16], [17]

Overdose

Special information about a possible overdose Nazol baby is not provided. Theoretically, it is possible to assume the appearance of such symptoms as heart rhythm disorders, headache, heaviness in the legs, high blood pressure, irritability.

[21]

Interactions with other drugs

The vasoconstrictor effect of phenylephrine can be enhanced after combined use with MAO inhibitor drugs (eg, procarbazine) or with tricyclic antidepressants.

Hormonal thyroid drugs increase the risk of developing cardiac insufficiency, especially if there is coronary atherosclerosis.

[22], [23]

Storage conditions

Baby nasol is stored at an ordinary temperature not exceeding + 30 ° C. When choosing a storage location, account should be taken of the lack of free access of children to medicines.

[24], [25]

Shelf life

Shelf life Nazol baby - up to 2 years, after which the drops should be disposed of.

[26],