Nazik

The drug Nazik is an effective nasal remedy for external use. Nazik is a xylometazoline derivative and is prescribed for the treatment of upper respiratory tract diseases.

Indications Nazik

Nazik can be used:

• with swelling of the nasal mucosa, which accompanies acute rhinitis;
• in case of mechanical damage to the mucous membranes in the nasal cavity and on the inner surfaces of the wings of the nose;
• with vasomotor rhinitis;
• for swelling of the mucous membrane after surgical interventions in the nasal cavity.

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Release form

Nazik is available as an intranasal spray, 10 ml in a bottle with a nozzle for spraying the medicine. The medicine is a clear, colorless solution with the main ingredients xylometazoline and dexpanthenol. One spray usually contains 0.1 mg of xylometazoline and 0.5 g of dexpanthenol. The drug is available without a prescription.

Pharmacodynamics

Nazik is a complex drug that combines the action of a sympathomimetic and a vitamin B5 analogue. This combination allows for a vasoconstrictive and anti-edematous effect.

Xylometazoline hydrochloride exhibits sympathomimetic properties, improving nasal breathing and accelerating the removal of mucus from the nose.

Dexpanthenol has bioactivity similar to vitamin B5. This vitamin accelerates metabolic processes, promotes the production of antibodies and strengthens immunity at the local level.

In addition, the drug Nazik provides protection of the superficial mucous layers and helps wounds heal faster.

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Pharmacokinetics

The effect of the drug is observed within 5-10 minutes after spraying.

Some of the active ingredient xylometazoline is absorbed systemically, which may affect the functioning of the nervous and cardiovascular systems.

Dexpanthenol binds to plasma proteins and is distributed throughout the circulatory system. It is estimated that approximately 65% of the dose is excreted via the kidneys and about 35% in the faeces.

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Dosing and administration

Nazik is prescribed to adult patients or children over six years of age. The drug is sprayed into each nostril up to 3 times a day. The bottle must be positioned vertically when spraying. Simultaneously with pressing, the patient should inhale sharply through the nose.

To avoid side effects, it is not recommended to use Nazik for more than one week in a row. Therefore, when treating chronic rhinitis, you should promptly replace drugs after consulting with your doctor.

Nazik should not be used in patients under six years of age. In pediatrics, it is recommended to use a special drug - Nazik for children.

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Use Nazik during pregnancy

Nazik is not recommended for use by pregnant and lactating women, as studies on the effect of the drug on the child's body and on the course of pregnancy have not been conducted.

Contraindications

The main contraindications that exclude the use of Nazik are:

• tendency to allergic reactions to the components of the drug;
• atrophic changes in the nasal mucosa;
• acute cardiovascular pathologies;
• thyroid disease;
• increased intraocular pressure;
• surgical interventions with exposure of the meninges;
• taking MAO inhibitor drugs;
• pregnancy and breastfeeding;
• children under 6 years of age.

Relative contraindications, in which Nazik is prescribed with great caution, are:

• presence of pheochromocytoma;
• taking medications that increase blood pressure;
• prostate hyperplasia;
• disorders of pigment metabolism (porphyrin disease).

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Side effects Nazik

The development of side effects may be observed with chaotic or prolonged use of the drug Nazik. Among the most common side effects are:

• irritability, sleep disturbances, feeling of constant fatigue, headaches;
• rapid heartbeat, high blood pressure, irregular heartbeat;
• convulsive syndrome;
• allergic reactions (rash, swelling);
• deterioration of visual functions;
• dyspeptic disorders;
• drying of the nasal mucosa, nosebleeds, burning.

After discontinuing the drug, side effects in most cases go away on their own and do not require additional treatment.

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Overdose

The use of Nazik in inappropriately large doses, as well as the use of the drug internally, can provoke a disruption of the nervous and cardiovascular systems, which manifests itself in spastic conditions, a slowing of the heart rate, a comatose state, difficulty breathing, and an increase in blood pressure.

The nervous system may react to an overdose of Nazik by causing anxiety, hallucinations, seizures, the development of depressive states and a decrease in body temperature.

Additional signs of overdose may include:

• constriction or dilation of the pupils;
• increased sweating;
• paleness of the skin;
• heart rhythm disturbances;
• shock, changes in blood pressure;
• respiratory dysfunction;
• disorders of consciousness.

When taking the drug internally, induce vomiting, take activated charcoal or a laxative. If necessary, symptomatic therapy is administered.

Interactions with other drugs

The combined use of Nazik with MAO inhibitors, β-blockers or antidepressants may provoke an increase in blood pressure due to the effect of these drugs on the cardiovascular system.

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Storage conditions

The drug Nazik does not require any specific storage conditions. However, children's access to the storage area of the drug should be limited.

Shelf life

The shelf life of a sealed medicine is up to 3 years. After opening, Nazik should be used within 4 months, after which the medicine should be thrown away.