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Meverin
Last reviewed: 03.07.2025
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Indications Meverina
It is used to carry out the following procedures:
- symptomatic measures that help relieve abdominal spasms and pain, as well as the feeling of discomfort, as well as disorders that develop with diagnosed IBS;
- elimination of spasms in the gastrointestinal tract that are secondary in nature – due to diseases of the gallbladder, liver, pancreas, and also the intestines.
Release form
The medication is released in capsules, in the amount of 30 pieces per pack.
Pharmacodynamics
Meverine is a selective myotropic antispasmodic with a pronounced effect on smooth muscles in the gastrointestinal tract. The substance mebeverine can eliminate muscle spasms inside the gastrointestinal tract, while not affecting the healthy function of intestinal peristalsis.
The medicine is prescribed to people suffering from digestive disorders, in which pain of a spastic nature is observed, and in addition to this, for the treatment of organic diseases of the digestive organs, with the development of secondary spasms in the gastrointestinal tract.
Inside smooth muscle cells, mebeverine administered in a medicinal dose blocks the membranes of Na channels, and at the same time prevents the passage of sodium ions into the cells, and in addition, spasms in the area of smooth muscles of internal organs.
Compared to anticholinergic drugs, the medication does not affect M-cholinergic receptors and does not cause side effects typical for this category of antispasmodics (such as visual disturbances, delayed urination, and dry mouth). This allows it to be used for enlarged prostate and glaucoma. At the same time, the use of the drug does not lead to the formation of intestinal hypotension, which has a reflex origin.
Pharmacokinetics
After taking the capsule orally, the drug undergoes a process of presystemic hydrolysis. The substance is not registered in the blood plasma. Metabolism occurs in the liver, resulting in the formation of mebeverine alcohol together with veratric acid.
Most of the drug is excreted through the kidneys - in the form of dimethylcarboxylic and carboxylic acids. A smaller part is excreted with bile.
Long-term release of the active element from capsules still does not cause its significant accumulation.
Dosing and administration
The medicine should be taken in a 0.2 g portion (the volume of 1 capsule), twice in 24 hours. It is recommended to take the drug 20 minutes before meals.
The capsules should be swallowed whole with plain water. The duration of the treatment course is selected taking into account the severity of the disease and symptoms.
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Use Meverina during pregnancy
Meverin should be used during lactation or pregnancy only as indicated and under the supervision of a doctor.
Contraindications
Main contraindications:
- intestinal obstruction of a paralytic nature;
- the presence of hypersensitivity to mebeverine or other components of the drug.
Overdose
In cases of mebeverine poisoning, signs of potentiation of CNS excitability were often observed, which were quickly eliminated.
To eliminate the disorder, gastric lavage should be performed, and then symptomatic measures should be taken (if necessary).
Storage conditions
Meverin is kept in standard conditions for medicines. Temperature marks are within 15-25°C.
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Shelf life
Meverin can be used for 2 years from the date of manufacture of the therapeutic agent.
Application for children
Prescribing the medication to people under 18 years of age is prohibited.
Analogues
The analogs of the drug are Tribudat with Tribux, and also Trigan and Trimspa.
Reviews
Meverin usually receives positive reviews. The drug copes well with the manifestations of IBS, and in addition with the signs of spasms in the gastrointestinal tract, which are of a secondary nature. It does not affect healthy intestinal function and almost does not cause negative manifestations.
But it is important to remember that this medication can only temporarily alleviate the course of the disease and cannot be considered a primary therapy drug. It should also be remembered that only a gastroenterologist can prescribe drugs.
Attention!
To simplify the perception of information, this instruction for use of the drug "Meverin" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.